A Rare Cause of Thoracic Spinal Cord Compression by Multiple Large Tarlov Cysts

Ahmed-Salem Kleib,Sidi-Mohamed Salihy,Hussein Hamdi,Romain Carron,Outouma Soumaré,Ahmed-Salem Kleib 대한신경손상학회 2018 Korean Journal of Neurotrauma Vol.15 No.1

Spinal extradural arachnoid cyst (SEAC) is a rare cause of spinal cord compression. Bifocal location of thoracic and sacralSEACs is rarely reported in the literature. We report a case of thoracic spinal cord compression by SEAC associated withasymptomatic multiple sacral Tarlov cysts (TC). The surgical management and postoperative outcome of the patient arediscussed. A 34-year-old woman was referred to the hospital for acute thoracic pain with a history of chronic long-standing back pain. She complained of walking diffculties. Neurological examination demonstrated incomplete spastic paraplegia with sensory level in T9. Magnetic resonance imaging revealed a large cystic formation from T7-11 and at the levelof the sacrum. We performed laminectomies at the level of interest from T7-11. The cysts were dissected from the underlying dura after removal of the cerebrospinal fluid. We found nerve tissue in the cysts. We excised the cyst and preservedthe nerve roots. Subsequently, a duraplasty was performed with autologous grafts from the lumbar fascia. The conditionof the patient improved after surgery and he was recovering well at follow-up. Although the surgical treatment of TC iscontroversial, especially at the sacral lumbar level, decompression at the dorsal level in this case is indisputable

Camellia sinesis leaves extract ameliorates high fat diet-induced nonalcoholic steatohepatitis in rats: analysis of potential mechanisms

Mohamed Safaa H.,Shahat Abdelaaty A.,Mohamed Mohamed Ragaa,Khalil Wagdy K. B.,Salem Ahmed M.,Farrag Abdel Razik H.,Ahmed Hanaa Hamdy 한국약제학회 2021 Journal of Pharmaceutical Investigation Vol.51 No.2

Purpose Our research aims to address and determine the effect of Camellia sinensis extract in the management of nonalcoholic steatohepatitis (NASH) in rats. Methods Forty adult female albino rats were divided into four groups. Group 1 (G1) served as the control group, while the other three groups received high-fat diet for 32 weeks to induce NASH and then were later assigned to the following groups: (G2) NASH-afflicted group which was left untreated, (G3) NASH-afflicted group treated with Camellia sinensis extract in a dose of 400 mg/kg, and (G4) NASH-afflicted group treated with Camellia sinensis extract in a dose of 200 mg/kg. Results Significant elevation in serum alanine aminotransferase, albumin, bilirubin (total and direct), cholesterol, low density lipoprotein, triglycerides, leptin, Cox-2, and CD40 values was recorded. Moreover, overexpression of hepatic tumor necrosis factor alpha and hepatocyte growth factor genes were recorded, whereas blood platelet count and serum high density lipoprotein concentration revealed significant depletion, which was paralleled by significant downregulation of hepatic adiponectin gene expression level in NASH group versus the control group. On the opposite side, treatment of NASH groups with two different doses of Camellia sinensis extract reversed the values of the measured biochemical parameters and the targeted gene expression levels when compared with the NASH group. Optical micrograph of liver tissue sections of rats treated with Camellia sinensis extract showed the observed improvement in the studied biochemical and genetic markers. Conclusion This study provides a clear evidence for the promising therapeutic potential of Camellia sinensis extract against NASH. This could be ascribed to its hepatoprotective activity, hypolipidemic effect, and anti-inflammatory potency.

Continuance Adoption of Working from Home after the COVID-19 Outbreak: Empirical Evidence from Saudi Arabia

Salem Mohamed AHMED,Nor KHALIL MD 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.7

The COVID-19 pandemic sweeping the world has rendered a large proportion of the workforce unable to commute to work, to mitigate the spread of the virus. This has resulted in both employers and employees seeking alternative work arrangements. Due to the pandemic, most if not all workers experienced work from home Hence work from home has become a policy priority for most governments. Individuals have started to change their behavior to stick to the curfew and rapidly conform to the new way of life. This study is conducted to understand how organizations and people adjust to these developments and challenges. Numerous organizations are changing to the online method of working because of the COVID-19. Because of the continuous adoption of a specific behavior after the COVID-19 pandemic situation ended, employees were expected to continue working from home. To investigate deep into the behavioral consequences of such a pandemic situation, in-depth interviews were conducted in several companies in Saudi Arabia. This study was conducted by extending the Theory of Planned Behavior (TPB) and the theory of reasoned action (TRA) to explore and assess the various factors that determine the continuous adoption intention of work-from-home by the Saudis. The finding shows that the employees’ positive attitude, subjective norms, and self-efficacy affect the employees’ intention to adopt work from home. The continuous adoption of work from home has been affected by employees’ relevant intention and controllability.

Investigating Islamic Studies Teachers' Attitudes Towards Utilizing Virtual Learning Environment in Distance Teaching among Primary Stage Pupils

Osama Mohamed Ahmed Salem,Mohammed bin Muthayb Al-Baqami International Journal of Computer ScienceNetwork S 2023 International journal of computer science and netw Vol.23 No.2

This research aimed at investigating Islamic Studies teachers' attitudes towards utilizing virtual learning environment in distance teaching among primary stage pupils. It also aimed at determining the statistical differences among variables due to sex, educational qualification, number of years of experience, and training sessions. This research adopted the descriptive approach. The sample consisted of male and female primary teachers of Islamic Studies (N=250) in governmental schools in Taif. The questionnaire was used as a main research tool. It included (20) items. Results showed that Islamic Studies teachers' attitudes towards utilizing virtual learning environment in distance teaching among primary stage pupils were ranked to a medium degree. There was a statistically significant difference among primary Islamic Studies teachers' attitudes due to sex variable. It was recommended to adopt more training sessions and seminars for adopting the idea of utilizing virtual learning environments among Islamic Studies teachers at boys' and girls' school in Mecca through emphasizing its significance and benefits in Teaching.

The Effect of an Educational Program Based on the 3D Glasses as a Technological Innovation on the Academic Achievement and Attitude towards E-Learning

Osama Mohamed Ahmed Salem,Noheir Taha Hassan Mohamed International Journal of Computer ScienceNetwork S 2023 International journal of computer science and netw Vol.23 No.1

The research aimed to identify the effectiveness of an educational program using 3D glasses as a technological innovation on academic achievement and attitude towards elearning in science in the preparatory stage. The research relied on the analytical descriptive approach and the semi-experimental approach. The research tools were the achievement test and the scale of attitude towards e-learning. An educational program was designed and produced using 3D glasses. The study sample consisted of 60 students from the second grade in the preparatory stage at the Rural Jeddah School. The research concluded to the following results: There was a satistically sigificant difference at the level of sig. (0.05) among the -mean scores of the experiemtal and control group students in the post assessment atthe level of achievement in favor of the experiemental group and therewas a satistically sigificant difference at the level of sig. (0.05) among mean scores of the experiemtal and control group students in the post assessment at the level of attitude towards e-learning in favor of the experiemental group. And it was found that the positive effect of the 3D educational program for improving the level of achievement and the attitude towards e-learning for the students. The program allowed the experimental group students to practice self-learning, interaction, and achievement according to the individual differences among them.

Archaeogeophysical investigation using magnetic and GPR surveys at Tal-Baltus, Menofia Governorate, Egypt

Ahmed Khalil,Khamis Mansour,Ahmed El Kotb,Hesham Zahra,Tareq Fahmy Abdallatif,Mohamed Salem,Marwa Shaheen 한국지질과학협의회 2023 Geosciences Journal Vol.27 No.5

An integrated geophysical survey using land magnetic and ground penetrating radar (GPR) methods was conducted to investigate the archaeological findings and ancient cultural relics at an undiscovered 100 m × 60 m in Tal-Baltus in El-Sadat city, Menofia Governorate, Egypt. The study area at Tal-Baltus was chosen among several archaeological hills in the Menofia governorate due to its archaeological significance in the Greco-Roman history of Egypt. The total area was first surveyed using the magnetic method, and then two small promising sites within this area were selected for the GPR survey. The obtained magnetic results showed the presence of remarkably high anomalies with different shapes of irregular geometry. Therefore, they are interpreted as ruins of old storage rooms related to an ancient harbor-shaped structure. Besides, numerous scattered pillars and column heads were also delineated and matched with remains of granite blocks in abundance in the study area, taking the same trend as the delineated magnetic anomalies. In addition, the GPR results highlighted several hyperbolas with variable amplitudes and sizes, which have been interpreted as the shallow foundation of a potential ancient harbor made of limestone. The comprehensive interpretation of the integrated magnetic and GPR surveys strongly suggests that the study area may be a part of an ancient harbor in addition to some other ancillary room-shaped structures used for cargo storage purposes and scattered portions of walls and pillars dating back to the Greco-Roman era.

Hibiscus sabdariffa L.: phytoconstituents, nutritive, and pharmacological applications

Mohamed A. Salem,Ahmed Zayed,Magy E. Beshay,Mesih Mirna M. Abdel,Khayal Reem F. Ben,Fady A. George,Shahira M. Ezzat 경희대학교 융합한의과학연구소 2022 Oriental Pharmacy and Experimental Medicine Vol.22 No.3

Hibiscus sabdariffa L. (HS) calyx extracts have been well-documented for the treatment of hypertension, liver dysfunctions, and diabetes among others. An updated concise review of HS regarding phytoconstituents, and involved putative mechanisms of potential biological activities is presented. HS showed other food and other industrial applications, including the preparation of metallic nanoparticles. These activities were explained by the presence of a broad spectrum of valuable phytochemicals, including the red pigments anthocyanins, phenolic, and organic acids and polyphenolics (e.g., flavonoids and tannins). Most of the bioactivities were found to be associated with anthocyanins-rich extracts. Anthocyanins were found to have various mechanisms for the treatment of hypertension, including direct vasodilation and inhibition of angiotensinconverting enzyme (ACE). However, leaves and seeds showed also other potential applications in food industry, owing to the significant amounts of phenolic antioxidant compounds. Therefore, valorization and optimization of bioactive constituents’ extraction from plant biowastes should be considered for maximizing the benefits of HS extracts.

Preparation of nylon-6/chitosan composites by nanospider technology and their use as candidate for antibacterial agents

Mohamed Hassan El-Newehy,Salem Slayyem Al-Deyab,Rajkumar Nirmala,Ahmed Abdel-Megeed,Hak Yong Kim 한국화학공학회 2013 Korean Journal of Chemical Engineering Vol.30 No.2

Electrospun nylon-6/chitosan (nylon-6/Ch) nanofibers were prepared by nanospider technology. Quaternary ammonium salts as antibacterial agent were immobilized onto electrospun nylon-6/Ch nanofibers via surface modification by soaking the mat in aqueous solution of glycidyltrimethylammonium chloride (GTMAC) at room temperature overnight to give nylon-6/N-[(2-hydroxy-3-trimethylammonium)propyl] chitosan chloride (nylon-6/HTCC). The morphological,structural and thermal properties of the nylon-6/ch nanofibers were studied by field-emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), Fourier transform-infrared (FT-IR) spectroscopy, and thermogravimetric analysis (TGA). Biological screening has demonstrated the antibacterial activity of the electrospun nanofibers against Gram negative bacteria, Escherichia coli 35218, and Pseudomonas aeruginosa and Gram positive bacteria,Staphylococcus aureus 24213 among the tested microbes. Thus, the study ascertains the value of the use of electrospun nanofibers, which could be of considerable interest to the development of new antibacterial materials for biomedical applications.

Study on the Effect of the Self-Attenuation Coefficient on γ-ray Detector Efficiency Calculated at Low and High Energy Regions

Ahmed. M. El-Khatib,ABOUZEID. A. THABET,MOHAMED. A. ELZAHER,MOHAMED. S. BADAWI,BOHAYSA. A. SALEM 한국원자력학회 2014 Nuclear Engineering and Technology Vol.46 No.2

The present work used the efficiency transfer method used to calculate the full energy peak efficiency (FEPE) curves ofthe (2"*2" & 3"*3") NaI (Tl) detectors based on the effective solid angle subtended between the source and the detector. Thestudy covered the effect of the self attenuation coefficient of the source matrix (with a radius greater than the detector's radius)on the detector efficiency. 152 An Eu aqueous radioactive source covering the energy range from 121.78 keV up to 1408.01keV was used. In this study an empirical formula was deduced to calculate the difference between the measured and thecalculated efficiencies [without self attenuation] at low and high energy regions. A proper balance between the measured andcalculated efficiencies [with self attenuation] was achieved with discrepancies less than 3%, while reaching 39% forcalculating values [without self attenuation] due to working with large sources, or for low photon energies.

MicroRNAs and Metastasis-related Gene Expression in Egyptian Breast Cancer Patients

Hafez, Mohamed M.,Hassan, Zeinab K.,Zekri, Abdel Rahman N.,Gaber, Ayman A.,Rejaie, Salem S. Al,Sayed-Ahmed, Mohamed M.,Shabanah, Othman Al Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2

Aim and background: MicroRNAs (miRNAs) are a class of naturally occurring small noncoding RNAs that regulate gene expression, cell growth, differentiation and apoptosis by targeting mRNAs for translational repression or cleavage. The present study was conducted to study miRNAs in Egyptian breast cancer (BC) and their relation to metastasis, tumor invasion and apoptosis in addition to their association with the ER and PR statuses. Methods: Real Time RT-PCR was performed to identify the miRNA expression level of eight miRNAs and eight metastatic-related genes in 40 breast cancer samples and their adjacent non-neoplastic tissues. The expression levels of each miRNA relative to U6 RNA were determined using the $^{2-{\Delta}}CT$ method. Also, miRNA expression profiles of the BC and their corresponding ANT were evaluated. Results: The BC patients showed an up-regulation in miRNAs (mir-155, mir-10, mir-21 and mir-373) with an upregulation in MMP2, MMp9 and VEGF genes. We found down regulation in mir-17p, mir-126, mir-335, mir-30b and also TIMP3, TMP1 and PDCD4 genes in the cancer tissue compared to the adjacent non-neoplastic tissues. Mir -10b, mir -21, mir-155 and mir373 and the metastatic genes MMP2, MMP9 and VEGF were significantly associated with an increase in tumor size (P < 0.05). No significant difference was observed between any of the studied miRNAs regarding lymph node metastasis. Mir-21 was significantly over-expressed in ER-/PR-cases. Conclusion: Specific miRNAs (mir-10, mir-21, mir-155, mir-373, mir-30b, mir-126, mir-17p, mir-335) are associated with tumor metastasis and other clinical characteristics for BC, facilitating identification of individuals who are at risk.