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RISS 인기검색어
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- 저자 : S. Nosoudi (검색결과 2 건)
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Association of a Synthetic Bone Graft and Bone Marrow Cells as a Composite Biomaterial
S. M. Rabiee,S. M. J. Mortazavi,F. Moztarzadeh,D. Sharifi,F. Fakhrejahani,A. Khafaf,S. A. Houshiar Ahmadi,N. Nosoudi,R. Ravarian 한국생물공학회 2009 Biotechnology and Bioprocess Engineering Vol.14 No.1
Porous calcium phosphates have osteoconductive properties. The aim of this study was to obtain synthetic calcium phosphate bone graft substitute. X-ray diffraction was employed to investigate the formation of the beta-tricalcium phosphate (β-TCP) phase. We evaluated the effects of bone marrow on the osteoconductivity and mechanical properties of synthetic bone graft (SG). SG cylinders loaded with bone marrow (SGBM) and SG alone were implanted into rabbits femoral condyle bone defects. Histological examinations revealed the resorption of the SG, trabecular bone with osteoblasts and osteoid substance around the implants, and colonization inside the porous β-TCP by newly formed bone. Histomorphometry conducted after three months revealed the osteoid surface to be higher in SGBM than SG (p < 0.05). The compressive strengths of SG and SGBM were significantly higher than the anatomic control at all time periods. The elastic modulus of SBG and SGBM became weaker after implantation. The present results indicate that β-TCP is a good matrix for bone marrow, which contributes osteoinductive properties in an orthotopic. The composite biomaterial may be useful in reconstructive bone surgery.
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M. H. Korayem,S. Nosoudi,S. Khazaei Far,A. K. Hoshiar 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.2
Nanomanipulation plays a significant role in nanotechnology research. The process of Atomic force microscopy (AFM) based manipulation is complex and time-consuming, which can be improved using a path-planning algorithm to reduce its manipulation time and time complexity. Due to real-time monitoring limitation in AFM based manipulations, Virtual reality (VR) environments have been developed. One such developed VR environment, however, is limited to point to point manipulation and lacks any path information. Therefore, we propose using a hybrid Improved particle swarm optimization (IPSO), a cellular automata-based algorithm for path planning during manipulation of micro/nanoparticles. In this technique, the critical time-force diagram, representing the AFM based manipulation dynamic is considered as a constraint, and is subsequently used to find the best path. The main path is divided into several segments and is optimized. Used as an algorithm for manipulation, this technique provides a more precise path in the AFM-based manipulation. Finally, the ability of this technique was compared to the other path planner algorithms based on its efficiency in reducing time-complexity parameters.
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