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      • KCI등재

        Migrant Workers’ Rights and Status under International Law: the Asian Experience

        Patricia R.P. Salvador Daway (사) 이준국제법연구원 2010 Journal of East Asia and International Law Vol.3 No.2

        The importance and extent of the migration phenomenon, affecting as it does huge numbers of people the world over cannot be overemphasized. Coming from third world countries, poverty-stricken and strangers in foreign lands, migrant workers irrespective of country of origin indeed become vulnerable to oppression and exploitation and all kinds of abuses. The question that needs to be addressed continues to be whether or not the existing ILO Conventions and Recommendations as well as the core international human rights treaties together with the International Convention on Migrant Workers have been adequately implemented in order to effectively address the problems related to the promotion and protection of migrant workers’rights. Given the flood of unabated reports and complaints of abuses and exploitation that migrant workers the world over have to suffer and contend with, the answer is quite obvious. While bilateral and multilateral agreements continue to serve the specific concerns of sending and receiving States pertinent to the protection of the rights of migrant workers, the real need is for a continent-wide forum in Asia which can eventually consolidate all mechanisms and measures that will promote and protect the rights of migrant workers in a truly comprehensive and integrated manner.

      • KCI등재

        Antioxidant, Mutagenic, and Antimutagenic Activity of Frozen Fruits

        Patricia D.S. Spada,Gabrielle Gianna Nunes de Souza,Giovana Vera Bortolini,Joao A.P. Henriques,Mirian Salvador 한국식품영양과학회 2008 Journal of medicinal food Vol.11 No.1

        Many studies have focused on the effect of fresh fruits on the risk of developing cancer and other diseases in-volved with reactive species and free radicals. The intake of frozen fruits has spread widely in the last years, but, until now,their biological activity is not completely known. In this study, 23 samples of frozen fruits were analyzed for their nutritionalcomposition, total polyphenols, total carotenoids, and vitamin C content. Antioxidant, mutagenic, and antimutagenic effectswere also evaluated. Antioxidant assays included 2,2-diphenyl-1-picrylhydrazyl radical (DPPH.) scavenging activity and de-termination of superoxide dismutase (SOD)- and catalase (CAT)-like activities. Mutagenic and antimutagenic evaluations wereperformed in eukaryotic cells of Saccharomyces cerevisiae yeast. Most samples (74%) showed antioxidant activity similar tovitamin C in the DPPH.assay, and this activity was positively correlated (r. 0.366; P. .01) with carotenoid contents. Allsamples showed CAT-like activity. SOD-like activity was detected in 56% of samples assayed. Only four fruits (acai, cashewapple, kiwi fruit, and strawberry) showed mutagenic activity when tested in high (5%, 10%, and 15% [wt/vol]) concentra-tions. Twelve samples presented antimutagenic effects against hydrogen peroxide, and this effect was positively correlatedwith CAT-like activity (r. 0.400; P. .01). Evaluation of polyphenols, carotenoids, and ascorbic acid showed considerablelevels of these compounds in frozen fruits, even after freezing. These data suggest that frozen fruits contribute to the pre-vention of biological damages.

      • KCI등재

        Frozen Fruit Pulp of Euterpe oleraceae Mart. (Acai) Prevents Hydrogen Peroxide-Induced Damage in the Cerebral Cortex, Cerebellum, and Hippocampus of Rats

        Patricia D.S. Spada,Caroline Dani,Giovana V. Bortolini,Claudia Funchal,João A.P. Henriques,Mirian Salvador 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.5

        Oxidative stress is implicated in several human illnesses, including neurological disorders such as Parkinson's and Alzheimer's diseases. Acai is largely consumed in Brazil and contains high levels of antioxidant compounds. This work aims to study the antioxidant activity of acai frozen fruit pulp in the cerebral cortex, hippocampus, and cerebellum of rats treated with the oxidizing agent hydrogen peroxide (H2O2). Pretreatment of tissue with acai decreased H2O2-induced damage of both lipids and proteins in all tissues tested. This fruit was also able to reduce the activities of the antioxidant enzymes superoxide dismutase and catalase to basal levels. We observed a negative correlation between the polyphenol content of acai and the levels of lipid (r=−0.689; P≤.05) and protein damage (r=−0.569; P≤.05), suggesting the participation of polyphenols in the observed antioxidant activity. These data suggest that acai has a positive contribution in the development of age-related neurodegenerative diseases.

      • KCI등재후보

        A case of COVID-19 immediately after liver transplantation: Not only bad news

        Mikel Prieto,Mikel Gastaca,Patricia Ruiz,Alberto Ventoso,Ibone Palomares,Regino Jose Rodriguez-Alvarez,Patricia Salvador,Javier Bustamante,Andres Valdivieso 한국간담췌외과학회 2020 Annals of hepato-biliary-pancreatic surgery Vol.24 No.3

        COVID-19, the illness caused by the SARS-CoV-2 virus originated in December 2019 in Wuhan, China and has caused more 3,3 million cases and more than 230,000 deaths throughout the world, with 25,000 of them only in Spain, where the first case was diagnosed on January 31st, 2020. As COVID-19 is a “new” disease, we still do not have data on prognosis or treatment in transplant patients or on how to manage immunosuppression in this complex scenario. We present a case of COVID-19 diagnosed during the early postoperative period in a recipient whose liver transplantation was performed on late March during the lockdown in Spain, with donor and recipient previously negative rRT-PCR to SARS-CoV-2. In the first post-operative week the patient suffered COVID-19 pneumonia that was treated with immunosuppression minimization, oral Hydroxycloroquine and Azithromycin with favorable outcome. The patient was discharged on POD 21 without complications. To date, few early post-liver transplantation SARS-CoV-2 infected recipients have been published, but only one was an early postoperative infection. In our case the outcome was favorable, even though it was an early post -liver transplantation COVID-19 in a frail patient.

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