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Lee Sung Won,Son Hwancheol,Lee Seung Wook,Cho Kang Su,문두건,Yang Dae Yul,Chung Woo Sik,Suh Jun-Kyu,Park Hyun Jun,Min Kweonsik,Moon Ki Hak,Park Kwangsung,Park Jong Kwan,Hyun Jae Seog,Yang Sang-Kuk 대한남성과학회 2022 The World Journal of Men's Health Vol.40 No.2
Purpose: To investigate the efficacy, safety, and tolerability of oro-dispersible film (ODF) formulation of mirodenafil 50 mg and 100 mg for the treatment of patients with erectile dysfunction (ED) in Korea. Materials and Methods:Materials and Methods: A multicenter, randomized, double-blind, placebo-controlled, parallel-group study of 129 subjects was per-formed. Subjects were randomized to either placebo or mirodenafil ODF 50 mg or 100 mg to be taken in an “on demand” manner for 8 weeks. The primary efficacy variable was the International Index of Erectile Dysfunction (IIEF)-5 questionnaire. The secondary efficacy variables comprised Sexual Encounter Profile questions 2 and 3 (SEP2 and SEP3), the Global Assessment Question (GAQ), and the Life Satisfaction Checklist (LSC). Results:Results: IIEF-5 was significantly increased in all groups after treatment. However, compared to the placebo group, only the mirode-nafil ODF 100 mg group showed a significant difference. SEP2 and SEP3 were increased in both mirodenafil groups; however, the increase was not statistically significant for SEP2. In terms of GAQ and LSC, the mirodenafil ODF groups showed significant increases compared with the baseline. Most treatment-associated adverse events were mild and resolved spontaneously. Conclusions:Conclusions: Mirodenafil ODF is an effective and well-tolerated agent for the treatment of patients with ED in Korea.
4K-UHD 비디오 시청환경 특성분석을 위한 주관적 화질평가 분석
박인경(Inkyung Park),하광성(Kwangsung Ha),김문철(Munchurl Kim),조숙희(Sukhee Cho),최진수(Jin Soo Choi) 한국방송·미디어공학회 2010 방송공학회논문지 Vol.15 No.4
In this paper, we perform subjective visual quality assessments on UHD video for UHD TV services and analyze the assessment results. Demands for video services have been increased with availabilities of DTV, Internet and personal media equipments. With this trend, the demands for high definition video have also been increasing. Currently, 2K-HD (1920×1080) video have been widely consumed over DTV, DVD, digital camcoders, security cameras and other multimedia terminals in various types, and recently digital cinema contents of 4K-UHD(3840×2160) have been popularly produced and the cameras, beam projects, display panels that support for 4K-UHD video start to come out into multimedia markets. Also it is expected that 4K-UHD service will appear soon in broadcasting and telecommunications environments. Therefore, in this paper, subjective assessments of visual quality on resolutions, color formats, frame rates and compression rates have been carried to provide basis information for standardization of signal specification of UHD video and viewing environments for future UHDTV. As the analysis on the assessments, UHD video exhibits better subjective visual quality than HD by the evaluators. Also, the 4K-UHD test sequences in YUV444 shows better subjective visual quality than the 4K-UHD test sequences in YUV422 and YUV420, but there is little perceptual difference on 4K-UHD test sequences between YUV422 and YUV420 formats. For the comparison between different frame rates, 4K-UHD test sequences of 60fps gives better subjective visual quality than those of 30fps. For bit-depth comparison, HD test sequences in 10-bit depth were little differentiated from those in 8-bit depth in subject visual quality assessment. Lastly, the larger the PSNR values of the reconstructed 4K-UHD test sequences are, the higher the subjective visual quality is. Against the viewing distances, the differences among encoded 4K-UHD test sequences were less distinguished in longer distances from the display.
김정훈(Junghoon Kim),최광석(Kwangsung Choi),박성용(Sungyong Park),이장무(Jangmoo Lee),강상욱(Sangwook Kang),강주석(Juseok Kang) 한국자동차공학회 2005 한국 자동차공학회논문집 Vol.13 No.4
In most researches on the ride comfort analysis of passenger vehicles, the flexibility of the vehicle body has been not considered as an important factor, because the resonance frequencies of the vehicle body related to pitching, yawing and rolling motions are below 10 ㎐ while the resonance frequencies of the vehicle body related to the flexibility are above 20 ㎐ approximately. Nevertheless, the paper shows that the consideration of the local flexibility (or local stiffness) of the 4 corners on which shock absorbers are mounted influences the ride comfort. A simple beam model is devised to qualitatively examine the effect of the change of the local stiffness of the vehicle body on the ride comfort. Based on the results obtained from the analysis of the one-dimensional model, multi-body dynamic analysis considering the flexibility of the vehicle body is performed using ADAMS and MSC/NASTRAN. Natural frequencies and mode shapes computed by MSC/NASTRAN are used as input data for multi-body dynamic analysis in ADAMS. Through simulations using ADAMS, it has been found that the ride comfort can be improved by changing the local stiffness of the vehicle body and that the simulation results agree with experiment results.