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Safety and Reasonability of Liver Resection for Intrahepatic Cholangiocarcinoma in Elderly Patients
( Andrii Zhylenko ),( Oleksandr Hrinenko ),( Oleksandr Korshak ),( Oleksii Popov ),( Andrii Husiev ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: The incidence of intrahepatic cholangiocarcinoma (ICC) in elderly patients is increasing worldwide. Little is known regarding postoperative outcomes in elderly patients undergoing liver resection for ICC. Methods: 84 patients undergoing liver resection for ICC between 2004 and 2018 were identified. Perioperative characteristics, postoperative morbidity, mortality and survival were compared between elderly (>60 years, group 1, n=31) and non-elderly (<60 years, group 2, n=53) patients. Results: Gender (P =0,34) and body mass index distribution (P =0,61), duration of stay (P =0,071) were comparable between groups. Surgical characteristics and pathologic data we present in table 1. Incidence of surgical site infections (19,3% vs 18,8%, P =0,95), posthepatectomy liver failure (18,6% vs 22,6%, P =0,47), reoperation (9,6% vs 9,4%, P =0,97) and clinically relevant complications (29,1% vs 32,1%, P =0,77) were comparable between the different age groups. 3-year OS (29.1% vs 32,5%, P =0,06) and DFS (16,5% vs 18.4%, P =0,004) were comparable between the elderly and non-elderly patients. Conclusions: Liver resection for ICC in elderly patients can obtain acceptable perioperative morbidity rates with a chance of long-term survival.