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Ambarita Aulia Chintia,Mulyati Sri,Arahman Nasrul,Bilad Muhammad Roil,Gül Bahar Yavuztürk,Korkut Sevde,Koyuncu İsmail 한국화학공학회 2024 Korean Journal of Chemical Engineering Vol.41 No.4
Dragon blood resin (DBR) has been reported as an eff ective bio-based additive for polymeric membrane fabrication. It improves permeability and antifouling properties, but its weak chemical bond makes it susceptible to leaching. This study investigates the chemical stability and leaching behavior of polyethersulfone (PES) membranes modifi ed with DBR in an alkaline solution. The study involved immersing two types of PES-based membranes, one loaded with 3% DBR (M-3) during the fabrication and one without (M-0), in a 0.01-N NaOH solution for 5 days. The results show that M-0 had good resistance to high alkaline solutions, while M-3 was less stable. Pure water permeability and water contact angle increased with immersion time, with an average percentage increase of 90.74 and 19.48%, respectively. The leaching of DBR from the PES membrane could be attributed to its polarity and the breaking of the DBR bonds, causing them to break apart into smaller molecules. The leaching of DBR also leaves a void that increases the pore size. This report provides useful information for the optimal design of a bio-based PES membrane.
Mauleti Ifael Yerosias,Wibisana Krishna Adi,Syamsuridzal Djati Prasetio,Mulyati Sri,Lisdawati Vivi,Saptarini Ika,Nurhayati,Hasiguan Armedy Ronny,Hendarwan Harimat 대한예방의학회 2024 예방의학회지 Vol.57 No.3
Objectives: This study investigated factors associated with the retention of people living with human immunodeficiency virus (HIV) on antiretroviral therapy (ART) during the first 3 years of treatment.Methods: A retrospective study using electronic health records was conducted at a tertiary hospital in Jakarta, Indonesia. Adult HIV-positive patients who started ART from 2010 until 2020 were included. A binary logistic regression model was used to identify factors associated with ART retention in the first 3 years.Results: In total, 535 respondents were included in the analysis. The ART retention rates for the first, second, and third years were 83.7%, 79.1%, and 77.2%, respectively. The multivariate analysis revealed a negative association between CD4 count when starting ART and retention. Patients with CD4 counts >200 cells/mL were 0.65 times less likely to have good retention than those with CD4 counts ≤200 cells/mL. The year of starting ART was also significantly associated with retention. Patients who started ART in 2010-2013 or 2014-2016 were less likely to have good retention than those who started ART in 2017-2020, with adjusted odds ratios of 0.52 and 0.40, respectively. Patients who received efavirenz-based therapy were 1.69 times more likely to have good retention than those who received nevirapine (95% confidence interval, 1.05 to 2.72).Conclusions: Our study revealed a decline in ART retention in the third year. The CD4 count, year of enrollment, and an efavirenz-based regimen were significantly associated with retention. Patient engagement has long been a priority in HIV programs, with interventions being implemented to address this issue.