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On FEM modeling of piezoelectric actuators and sensors for thin-walled structures
Marinkovic, Dragan,Marinkovic, Zoran Techno-Press 2012 Smart Structures and Systems, An International Jou Vol.9 No.5
Thin-walled adaptive structures render a large and important group of adaptive structures. Typical material system used for them is a composite laminate that includes piezoelectric material based sensors and actuators. The piezoelectric active elements are in the form of thin patches bonded onto or embedded into the structure. Among different types of patches, the paper considers those polarized in the thickness direction. The finite element method (FEM) imposed itself as an essential technical support for the needs of structural design. This paper gives a brief description of a developed shell type finite element for active/adaptive thin-walled structures and the element is, furthermore, used as a tool to consider the aspect of mesh distortion over the surface of actuators and sensors. The aspect is of significance for simulation of behavior of adaptive structures and implementation of control algorithms.
On FEM modeling of piezoelectric actuators and sensors for thin-walled structures
Dragan Marinkovic,Zoran Marinkovic 국제구조공학회 2012 Smart Structures and Systems, An International Jou Vol.9 No.5
Thin-walled adaptive structures render a large and important group of adaptive structures. Typical material system used for them is a composite laminate that includes piezoelectric material based sensors and actuators. The piezoelectric active elements are in the form of thin patches bonded onto or embedded into the structure. Among different types of patches, the paper considers those polarized in the thickness direction. The finite element method (FEM) imposed itself as an essential technical support for the needs of structural design. This paper gives a brief description of a developed shell type finite element for active/adaptive thin-walled structures and the element is, furthermore, used as a tool to consider the aspect of mesh distortion over the surface of actuators and sensors. The aspect is of significance for simulation of behavior of adaptive structures and implementation of control algorithms.
Cvjeticanin, Suzana,Marinkovic, Dragoslav 한국유전학회 2005 Genes & Genomics Vol.27 No.1
Our study of genetic homozygosity degree includes an analysis of the presence, distribution and individual combination of 20 to 30 selected genetically controlled morpho-physiological traits in the four samples of patients from Belgrade affected with different diseases (OLD-congenital hip dislocation N = 93, DM-diabetes mellitus N = 95, TBC-tuberculosis N = 79, BC-bronchogen carcinoma N = 109). Taking into consideration our experience, as well as the experience of numerous scientists studying the nature of the inheritance of mono- and oligo-genetically controlled qualitative traits, we applied this methodology to estimate the proportion of such homozygously recessive characteristics (HRC-test). This population-genetic study did not only show statistically significant difference in the middle value of genetic homozygosity (CHD - 7.1±0.1, control - 5.2±0.1 ; DM - 6.3±0.3, control - 4.4±0.2 ; TBC - 6.1±0.3, BC - 5.9±0.3, control - 4.9±0.3), but also in the differences in the distribution type, as well as the differences in the presence of certain individual combinations of such traits. Further applications of HRC-testing may have practical use in genetic counselling, since homozygosity seems to be correlated with an individual's susceptibility to different diseases. The frequency of ABO blood types in the samples of patients with CUD, DM and BC were quite similar to the percentage of blood groups in the Serbian population. In the sample of TBC-affected patients, O blood group is almost significantly on the decrease, while the other blood groups are slightly on the increase, according to the average value of those blood groups in Serbian popoulation.
COVID-19 and the Human Gut Microbiome: An Under-Recognized Association
Abu Fahad Abbasi,Aleksandra Marinkovic,Stephanie Prakash,Adekunle Sanyaolu,Stella Smith 전남대학교 의과학연구소 2022 전남의대학술지 Vol.58 No.3
Coronavirus disease 2019 (COVID-19) is an infectious disease with a wide range of respiratory and extrapulmonary symptoms, as well as gastrointestinal symptoms. Despite recent research linking gut microbiota to infectious diseases like influenza, minimal information is known about the gut microbiota’s function in COVID-19 pathogenesis. Studies suggest that dysbiosis of the gut microbiota and gut barrier dysfunction may play a role in COVID-19 pathogenesis by disrupting host immune homeostasis. Regardless of whether patients had taken medication or disease severity, the gut microbiota composition was significantly altered in COVID-19 patients compared to non-COVID-19 individuals. Several gut commensals with recognized immunomodulatory potential, such as Faecalibacterium prausnitzii, Eubacterium rectale, and bifidobacteria, were underrepresented in patients and remained low in samples taken several weeks after disease resolution. Furthermore, even with disease resolution, dysbiosis in the gut microbiota may contribute to chronic symptoms, underscoring the need to learn more about how gut microbes play a role in inflammation and COVID-19.
Cigarette Smoking and Breast Cancer: a Case-control Study in Serbia
Ilic, Milena,Vlajinac, Hristina,Marinkovic, Jelena Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11
Background: Despite the fact that breast cancer is the most common female cancer worldwide, more than half of the breast cancer risk factors remained unexplained. The aim of this study was to investigate the association of cigarette smoking with risk of breast cancer. Materials and Methods: A case-control study was conducted in the Clinical Centre of Kragujevac, Serbia, covering 382 participants (191 cases and 191 controls). In the analysis of data logistic regression was used. Results: Breast cancer risk was significantly increased in those who quit smoking at ${\leq}50$ years of age (OR=2.72; 95% confidence interval - 95%CI=1.02-7.27) and in those who quit smoking less than 5 years before diagnosis of the disease (OR=4.36; 95%CI=1.12-16.88). When smokers were compared with nonsmokers without passive exposure to smoking, former smoking significantly increased breast cancer risk (OR=2.37; 95%CI=1.07-5.24). Risk for breast cancer was significantly increased in those who quit smoking at ${\leq}50$ years of age (OR=3.29; 95%CI=1.17-9.27) and in those who quit smoking less than 5 years before diagnosis of the disease (OR=5.46; 95%CI=1.34-22.28). Conclusions: These data suggest that cigarette smoking is associated with an elevated risk of breast cancer among former smokers in Serbia.
Linear shell elements for active piezoelectric laminates
Gil Rama,Dragan Z. Marinkovic,Manfred W. Zehn 국제구조공학회 2017 Smart Structures and Systems, An International Jou Vol.20 No.6
Piezoelectric composite laminates are a powerful material system that offers vast options to improve structural behavior. Successful design of piezoelectric adaptive structures and testing of control laws call for highly accurate, reliable and numerically efficient numerical tools. This paper puts focus onto linear and geometrically nonlinear static and dynamic analysis of smart structures made of such a material system. For this purpose, highly efficient linear 3-node and 4-node finite shell elements are proposed. Both elements employ the Mindlin-Reissner kinematics. The shear locking effect is treated by the discrete shear gap (DSG) technique with the 3-node element and by the assumed natural strain (ANS) approach with the 4-node element. Geometrically nonlinear effects are considered using the co-rotational approach. Static and dynamic examples involving actuator and sensor function of piezoelectric layers are considered.
Reactogenicity to COVID-19 vaccination in the United States of America
Adekunle Sanyaolu,Aleksandra Marinkovic,Stephanie Prakash,Priyank Desai,Nafees Haider,Abu Fahad Abbasi,Nasima Mehraban,Isha Jain,Amarachi Ekeh,Omar Shazley,Chuku Okorie,Verner N. Orish 대한백신학회 2022 Clinical and Experimental Vaccine Research Vol.11 No.1
Purpose: In the United States, Pfizer-BioNTech, Moderna, and Janssen’s coronavirus disease 2019 (COVID-19) vaccines have been granted Emergency Use Authorization (EUA) with the Pfizer-BioNTech vaccine presently approved by the US Food and Drug Administration. The purpose of this study is to analyze passive surveillance data on COVID-19 vaccine adverse reaction in the United States. Materials and Methods: We analyzed passive surveillance data on COVID-19 vaccine adverse reactions which were retrieved from the Vaccine Adverse Event Reporting System database. Retrieved records on demographic information as well as the top 10 common vaccine adverse events were extracted and assessed from 200 of the most recently reported cases for the study analysis. Results: Local and systemic adverse reactions were reported in the study. A significant difference (p<0.05) was recorded for the top 10 systemic reactions by age category (0.041) and by gender (0.002). Analysis of the top five systemic reactions, stratified by vaccine type yielded a significant difference (p<0.05) for chills (p=0.044), and when stratified by age group and type of vaccination received, it yielded a significant difference (p<0.05) for fatigue (p=0.023). Overall, Pfizer had 182 persons (91.0%) reporting adverse events, Moderna with 13 (6.5%), and Janssen with 5 (2.5%). Conclusion: Mild side effects were reported following vaccination with the EUA COVID-19 vaccines in the United States. Thus, continuous monitoring and reporting of all adverse events are recommended to ensure the safety of vaccination
Candida auris : An Overview of the Emerging Drug-Resistant Fungal Infection
Sanyaolu Adekunle,Okorie Chuku,Marinkovic Aleksandra,Abbasi Abu Fahad,Prakash Stephanie,Mangat Jasmine,Hosein Zaheeda,Haider Nafees,Chan Jennifer 대한감염학회 2022 Infection and Chemotherapy Vol.54 No.2
Candida auris is an invasive fungal pathogen that has been recognized globally as a serious health threat due to its extensive innate and acquired resistance to antifungal drugs. A growing number of emerging cases of C. auris have been reported with resistance to the standard antifungal treatments including azoles, echinocandins, and polyenes, making it difficult to treat. Unlike other Candida species, C. auris is challenging to diagnose using the standard laboratory methods and are typically prone to misidentification, resulting in inappropriate management. Consequently, C. auris infections have spread globally. The Centers for Disease Control and Prevention data showed that clinical cases of C. auris increased from 329 in 2018 to 1,012 in 2021. The incidence and prevalence of this invasive fungal infection are high in immunocompromised and hospitalized patients. Patients who had an organ transplant, are on immunosuppressive agents, are diabetic, recent antibiotic use, catheter use, and prolonged hospital or nursing homestays are vulnerable to C. auris infections. C. auris is rapidly spreading across healthcare settings globally and monitoring of its virulence as well as devising appropriate treatment approaches are thus highly required.