http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Anelise S.N. Formagio,Maria do Carmo Vieira,Luiz A.C. dos Santos,Clau´dia A.L. Cardoso,Mary Anny Foglio,Joao Ernesto de Carvalho,Magaiver Andrade-Silva,Caˆndida A.L. Kassuya 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.1
The essential oil from the leaves of Annona sylvatica (EOAS) was extracted by hydrodistillation, and the analysis was performed by gas chromatography–mass spectrometry. The main compounds identified in the EOAS were sesquiterpenes, such as hinesol, z-caryophyllene, β-maaliene, γ-gurjunene, silphiperfol-5-en-3-ol, ledol, cubecol-1-epi, and muurola-3,5-diene. Oral administration of the EOAS (20 and 200 mg/kg) and subcutaneous injection of dexamethasone (0.5 mg/kg, reference drug) significantly inhibited carrageenan- and complete Freund's adjuvant–induced mouse paw edema. The anticancer activity the EOAS showed growth inhibitory activity on all cell lines when administered in a high concentration. The EOAS inhibited the growth of human cancer cell lines with GI50 values in the range of 36.04–45.37 μg/mL on all of the cell lines tested. This work describes for the first time the anti-inflammatory and anticancer effects of the essential oil of A. sylvatica and its composition. Considering that drugs currently available for the treatment of inflammatory and cancer conditions show undesirable side-effects, the present results may have clinical relevance and open new possibilities for the development of novel anti-inflammatory and anticancer drugs.
Roberta Gomes Coelho,Neli Kika Honda,Maria do Carmo Vieira,Rosenei Louzada Brum,Fernando Roge´rio Pavan,Clarice Queico Fujimura Leite,Claudia Andre´a Lima Cardoso 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.5
Bromelia balansae (Family Bromeliaceae) is a medicinal plant commonly used in the central region of Brazil as a cough syrup and also eaten roasted. The methanolic extract of ripe fruits was analyzed by chromatographic methods and spectrometrically. Four glycoside flavonols were isolated: kaempferol-3-O-α-l-rhamnopyranoside (1), kaempferol-3-O-α-l-rhamnopyranosyl-(1→6)-β-d-glucopyranoside (2), quercetin-3-O-α-l-rhamnopyranosyl-(1→6)-β-d-glucopyranoside (3), and kaempferol 3,7-di-O-α-l-rhamnopyranoside (4). The resazurin microtiter assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis. The results showed a moderate activity of the methanolic extract with a minimal inhibitory concentration of 128μg/mL. Antioxidant activity was evaluated as free radical scavenging capacity and inhibition of peroxidation. Free radical scavenging capacity was assessed by measuring the scavenging activity of methanolic extract and methanolic fraction on 2,2-diphenyl-1-picrylhydrazyl radical. The methanolic extract showed low values of antioxidant activities, whereas the methanolic fraction exhibited free radical scavenging activity ranging from 20.2% to 91.1%, and the inhibition of peroxidation values ranging from 5.6% to 27.5%. This is the first chemical study reported in the literature about this species.
Claudia Andréa Lima Cardoso,Gustavo Ruivo Salmazzo,Neli Kika Honda,Crislaine Batista Prates,Maria do Carmo Vieira,Roberta Gomes Coelho 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.5
The antimicrobial activity of the hexanic extracts and fractions of fruits of Campomanesia pubescens pubescens (D.C) O. Berg and Campomanesia adamantium (Cambess.) O. Berg were assayed against six microorganisms. The hexanic extracts of C. pubescens and C. adamantium fruits were also investigated in their composition by gas chromatography-mass spectrometry and high-performance liquid chromatography with diode array detection. The results of this study showed the presence of 34 volatile compounds and flavonoids in the hexanic extract of C. pubescens and 33 volatile compounds and flavonoids in the hexanic extract of C. adamantium.