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      • KCI우수등재

        The application of augmented reality for improving clinical skills: a scoping review

        Mahmud Mahmud,Sari Dwi Cahyani Ratna,Sari Djayanti,Arfian Nur,Zucha Muhammad Ary 한국의학교육학회 2024 Korean journal of medical education Vol.36 No.1

        Augmented reality technology had developed rapidly in recent years and had been applied in many fields, including medical education. Augmented reality had potential to improve students’ knowledge and skills in medical education. This scoping review primarily aims to further elaborate the current studies on the implementation of augmented reality in advancing clinical skills. This study was conducted by utilizing electronic databases such as PubMed, Embase, and Web of Science in June 2022 for articles focusing on the use of augmented reality for improving clinical skills. The Rayyan website was used to screen the articles that met the inclusion criteria, which was the application of augmented reality as a learning method in medical education. Total of 37 articles met the inclusion criteria. These publications suggested that using augmented reality could improve clinical skills. The most researched topics explored were laparoscopic surgery skills and ophthalmology were the most studied topic. The research methods applied in the articles fall into two main categories: randomized control trial (RCT) (29.3%) and non-RCT (70.3%). Augmented reality has the potential to be integrated in medical education, particularly to boost clinical studies. Due to limited databases, however, any further studies on the implementation of augmented reality as a method to enhance skills in medical education need to be conducted.

      • SCOPUSKCI등재

        Effect of Agricultural Exports and Imports on Economic Growth in Bangladesh: A Study on Agribusiness Supply Chain

        Mostofa Mahmud HASAN(Mostofa Mahmud HASAN ),BM Sajjad HOSSAIN(BM Sajjad HOSSAIN ),Md. Abu SAYEM(Md. Abu SAYEM ),Mahnaz AFSAR(Mahnaz AFSAR ) 한국유통과학회 2022 유통과학연구 Vol.20 No.11

        Purpose: The purpose of this study was to determine the effect of agricultural exports and imports on economic growth in Bangladesh and propose an upgraded and customized model of the supply chain for agribusiness growth in Bangladesh to achieve plain sailing and systematic operation and financial gains at home and abroad. Research design, data, and methodology: All data in the research have been collected from secondary sources. Gross domestic product was used as the dependent variable and exports and imports of agricultural products were used as independent variables. Pairwise Granger causality was utilized to see the impact of the variable responsible for the economic growth in Bangladesh and the causal relationship between the variables analyzed was measured using Johansen co-integration test. Results: From the empirical analysis, the researchers observed that agricultural commodity imports and exports have a unidirectional impact on economic growth in Bangladesh and a long-run causal link with economic growth in Bangladesh. The suggested supply chain model of agnbusiness aids in achieving smooth operations, systematic management, and monetary gains both domestically and internationally. Conclusions: This paper contnbutes to the development of a more effective and profitable agribusiness supply chain in Bangladesh systematically through their theoretical and practical implications.

      • SCIESCOPUS

        Absorption Mechanism of a Physical Complex of Monomeric Insulin and Deoxycholyl-<small>l</small>-lysyl-methylester in the Small Intestine

        Mahmud, Foyez,Jeon, Ok-Cheol,Al-Hilal, Taslim A.,Kweon, Seho,Yang, Victor C.,Lee, Dong Soo,Byun, Youngro American Chemical Society 2015 MOLECULAR PHARMACEUTICS Vol.12 No.6

        <P>Currently, oral administration of insulin still remains the best option to avoid the burden of repeated subcutaneous injections and to improve its pharmacokinetics. The objective of the present investigation was to demonstrate the absorption mechanism of insulin in the physical complexation of deoxycholyl-<SMALL>l</SMALL>-lysyl-methylester (DCK) for oral delivery. The oral insulin/DCK complex was prepared by making a physical complex of insulin aspart with DCK through ion-pair interaction in water. For the cellular uptake study, fluorescein-labeled insulin or DCK were prepared according to a standard protocol and applied to Caco-2 or MDCK cell lines. For the PK/PD studies, we performed intrajejunal administration of different formulation of insulin/DCK complex to diabetic rats. The resulting insulin and DCK complex demonstrated greatly enhanced lipophilicity as well as increased permeation across Caco-2 monolayers. The immunofluorescence study revealed the distribution of the complex in the cytoplasm of Caco-2 cells. Moreover, in the apical sodium bile acid transporter (ASBT) transfected MDCK, the insulin/DCK complex showed interaction with ASBT, and also demonstrated absorption through passive diffusion. We could not find that any evidence of endocytosis in relation to the uptake of insulin complex in vitro. In the rat intestine model, the highest absorption of insulin complex was observed in the jejunum at 1 h and then in the ileum at 2–4 h. In PK/PD study, the complex showed a similar PK profile to that of SC insulin. Overall, the study showed that the effect of DCK on enhancing the absorption of insulin resulted from transcellular processes as well as bile acid transporter activity.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/mpohbp/2015/mpohbp.2015.12.issue-6/mp500626a/production/images/medium/mp-2014-00626a_0009.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/mp500626a'>ACS Electronic Supporting Info</A></P>

      • Analysis of forces in an automobile ECV using in external variable displacement swash plate type compressor for air conditioning control system

        Mahmud, Md. Iqbal,Cho, Haeng Muk 대한기계학회 2014 KSME journal Vol. No.

        To meet the demand of improved comfort for passengers, drive ability and standard in fuel economy; external variable displacement swash (wobble) plate type compressors are used in automobile air conditioning control system because of their low energy consumption and highly efficient characteristics. It controls the compressor displacement by increasing or reducing the swash plate angle. Solenoid operated electromagnetic control valve (ECV) in the compressor controls the air conditioning system by means of a pulse width modulation (PWM) input signal supplied from an external source (controller). The mechanism changes the swash plate angle by increasing or reducing the pressure of swash plate chamber using the ECV functions. The force (solenoid) for ECV operation is important as the force directly related to the movement of the internal feature i.e. mainly plunger of the ECV which is responsible for the amount of air/refrigerant flow that results the air conditioning control procedures with various pressure ports. The research paper highlights the improved theory and equation for calculating the working force (solenoid force) in ECV and experimental analysis of 3 (three) ECV samples followed by the comparison of theoretical and experimental force results.

      • KCI등재
      • KCI등재SCOPUS

        Analysis on Literature Review of Internet of Things Adoption Among the Consumer at the Individual Level

        Mahmud, Arif,Husin, Mohd Heikal,Yusoff, Mohd Najwadi Korea Institute of Science and Technology Informat 2022 Journal of Information Science Theory and Practice Vol.10 No.2

        The research in the literature review on Internet of Things (IoT) adoption from an individual consumer viewpoint is minimal and has not yet been fully investigated. Therefore, the objectives of this study are to analyze the growth of IoT in recent years and to conduct a weight analysis of the factors that affect acceptance intentions and real usage of IoT-enabled services. For the review, we analyzed 87 publications from 13 conferences and 54 journals published during the period 2014-2020 about consumer adoption of IoT. Following the study, we discovered an unprecedented increase in the number of articles published in the last seven years, which points to an emerging area with an enormous prospect. Furthermore, the weight analysis outcome was associated with the diagrammatic representation in this study. After that, this research developed a generalized consumer IoT adoption model based on the 12 best predictors derived from frequency count and weight analysis, which had the highest predictive power for calculating IoT adoption. This paper further acknowledges the study's theoretical and practical contributions, as well as its shortcomings, and proposes further research directions for future researchers.

      • KCI등재

        Micro modelling of masonry walls by plane bar elements for detecting elastic behavior

        Mahmud Sami Döven,Uğur Kafkas 국제구조공학회 2017 Structural Engineering and Mechanics, An Int'l Jou Vol.62 No.5

        Masonry walls are amongst the oldest building systems. A large portion of the research on these structures focuses on the load-bearing walls. Numerical methods have been generally used in modelling load-bearing walls during recent years. In this context, macro and micro modelling techniques emerge as widely accepted techniques. Micro modelling is used to investigate the local behaviour of load-bearing walls in detail whereas macro modelling is used to investigate the general behaviour of masonry buildings. The main objective of this study is to investigate the elastic behaviour of the load- bearing walls in masonry buildings by using micro modelling technique. In order to do this the brick and mortar units of the masonry walls are modelled by the combination of plane truss elements and plane frame elements with no shear deformations. The model used in this study has fewer unknowns then the models encountered in the references. In this study the vertical frame elements have equivalent elasticity modulus and moment of inertia which are calculated by the developed software. Under in-plane static loads the elastic displacements of the masonry walls, which are encountered in literature, are calculated by the developed software, where brick units are modelled by plane frame elements, horizontal joints are modelled by vertical frame elements and vertical joints are modelled by horizontal plane truss elements. The calculated results are compatible with those given in the references.

      • SCISCIESCOPUS

        Oral pemetrexed facilitates low-dose metronomic therapy and enhances antitumor efficacy in lung cancer

        Mahmud, Foyez,Jeon, Ok-Cheol,Alam, Farzana,Maharjan, Ruby,Choi, Jeong Uk,Park, Jooho,Lee, Sojung,Park, Jin Woo,Lee, Dong Soo,Byun, Youngro Elsevier 2018 Journal of controlled release Vol.284 No.-

        <P><B>Abstract</B></P> <P>There is a growing interest in preclinical research to consider low-dose metronomic chemotherapy as antiangiogenic cancer treatment. Oral metronomic therapy, in particular, has shown much promise with its ease of daily administration and higher therapeutics window. In that regard, we developed oral pemetrexed using the physical complex with the bile acid enhancers (DCK). In a caco-2 permeability study, the oral pemetrexed/DCK complex had significantly higher drug uptake, and inhibited efflux transporter activity as well. We further observed that the mechanism of oral drug uptake was related to transcellular along with bile acid transporter mediated pathways. The oral administration of drug complex in rats revealed high bioavailability (22.37%) and extended mean residence time. Using SCC7 and A549 xenograft models, we demonstrated that antitumor effects from daily oral metronomic pemetrexed significantly reduced tumor in a dose-dependent manner. The antitumor activity of oral pemetrexed/DCK complex plus cisplatin was superior to both monotherapies. The xenograft study also revealed that oral metronomic therapy markedly reduced microvessel density, proliferation and increased apoptosis in the tumor tissues. Oral metronomic doses were significantly correlated with the elevation of plasma deoxyuridine level, an essential biomarker for pemetrexed therapy. One-month toxicity study confirmed that daily dosing of oral pemetrexed is safe by investigating apoptosis in the gut tissues from mice. Moreover, we analyzed different biochemical parameters and enzymes from the blood to prove that our newly developed oral pemetrexed complex is well tolerated.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

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