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        HEMATOLOGICAL RESPONSE OF SAUDI ARABIAN FOWL TO PROTEIN REARING REGIMENS

        Alsobayel, A.A.,Attia, F.M.,Bayoumi, M.S.,Haroun, I.Y. Asian Australasian Association of Animal Productio 1990 Animal Bioscience Vol.3 No.2

        The purpose of this investigation was to study the hematological response of Saudi Arabian Baladi fowl to protein rearing regimens. Males and females were subjected to the following 4 protein rearing regimens: conventional, C; reverse protein, RP; 2 single-stage low protein, $SS_1$ and $SS_2$ using 15% and 12% CP diets, respectively. Regimen effect was highly significant ($$p{\leq_-}.01$$) on BW, PCY, TP and U-Ac and significant ($$p{\leq_-}.05$$) on TL. Serum chol levels were not affected by regimen. In general $SS_{2}$ birds showed the lowest values for all parameters studied, except for PCV. However, the differences were not significant in each case. Age and sex effects were highly significant ($$p{\leq_-}.01$$) for all parameters, however, the regimen X sex interaction was not significant except for PCV. Regimen X age interaction, on the other hand, was highly significant ($$p{\leq_-}.01$$) only for BW, TP and U-Ac concentrations. The data may suggest that low levels of protein in the rearing regimen is an important factor influencing levels of the blood parameters studied. The data also indicate a lack of clear relationship between hen-day egg production and the blood parameters studied.

      • KCI등재후보

        Effect of FRP composites on buckling capacity of anchored steel tanks

        H. Ramadan,M.A. Al-Kashif,A. Rashed,M.A. Haroun 국제구조공학회 2010 Steel and Composite Structures, An International J Vol.10 No.4

        Enhancement in the seismic buckling capacity of steel tanks caused by the addition of fiber reinforced polymers (FRP) retrofit layers attached to the outer walls of the steel tank is investigated. Threedimensional non-linear finite element modeling is utilized to perform such analysis considering non linear material properties and non-linear large deformation large strain analysis. FRP composites which possess high stiffness and high failure strength are used to reduce the steel hoop stress and consequently improve the tank capacity. A number of tanks with varying dimensions and shell thicknesses are examined using FRP composites added in symmetric layers attached to the outer surface of the steel shell. The FRP shows its effectiveness in carrying part of the hoop stresses along with the steel before steel yielding. Following steel yielding, the FRP restrains the outward bulging of the tank and continues to resist higher hoop stresses. The percentage improvement in the ultimate base moment capacity of the tank due to the addition of more FRP layers is shown to be as high as 60% for some tanks. The percentage of increase in the tank moment capacity is shown to be dependent on the ratio of the shell thickness to the tank radius (t/R). Finally a new methodology has been explained to calculate the location of Elephant foot buckling and consequently the best location of FRP application.

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        Biochemical and histopathological studies of sulfonylurea derivative as a new chemotherapeutic agent against liver cancer in free‑ and nano‑coated forms

        Sroor Farid M.,Basyouni Wahid M.,Aly Hanan F.,Younis Eman A.,Mahrous Karima F.,Haroun Ahmed A. 한국응용생명화학회 2022 Applied Biological Chemistry (Appl Biol Chem) Vol.65 No.6

        The most frequent type of primary liver cancer is hepatocellular carcinoma (HCC), accounting for approximately 90% of primary liver cancers and a third leading cause of cancer deaths. In the current study, the synthesized compound 3 was re-formulated using tetraethyl orthosilicate (TEOS) with weight ratio (1:1) via sol-gel technique. The prepared material has been examined using Fourier transform infrared spectroscopy (FTIR), energy dispersive X-ray elemental analysis (EDX), and scanning and transmission electron microscopes (SEM and TEM). Herein, we investigate the mode of action of 3 as potent anti-liver cancer in vivo as normal and nano-forms. Rats were given a single dosage of 50 mg/kg b.wt. of HCC through an intraperitoneal injection (ip). A single dosage of CCl4 (2 ml/kg IP) was also given to rats 2 weeks later. Several liver, tumor and oxidative stress biomarkers were detected including liver enzymes; alanine and aspartate aminotransferases (ALT and AST), alkaline phosphatse (ALP), gamma glutamyl transferase (GGT), glutathione (GSH), lipid peroxide (MDA), catalase (CAT), superoxide dismutase (SOD), total antioxidant capacity (TAC), α-fetoprotein and α-L-Fucosidase. Hepatic pathological pictures were also performed for the documentation of the presence of HCC and supported the biochemical results. Moreover, the DNA damage in liver tissues of male rats using comet assay was studied. The results showed that the HePG2 (− ve) group of rats exhibited a significant reduction (P < 0.05) in DNA damage values (9.30 ± 0.89) relative to other treatment groups. Nevertheless, the DNA damage values in the HePG2 (+ ve) and 5-flurouracil groups were significantly higher (P < 0.01) compared to the HePG2 (− ve) group. Additionally, HePG2 (coated 3) and HePG2 (3) groups exhibited significant decrease in the DNA damage compared to those in HePG2 (+ ve) group.

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