http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Regeneration and selection of root rot resistant Coleus forskohlii A threatened medicinal plant
M.George Manju,Subramanian R.B.,A.Prajapati Hiren 한국자원식물학회 2000 한국자원식물학회 학술심포지엄 Vol.2000 No.-
Aralia elata is found in mountain areas all over Korean peninsula. Aralia elata is the scientific name for Japanese angelica tree. The tree belongs to the family Araliaceae, commonly known as ginseng family. Bud sprouts from apical shoot tip of the plants are rich in flavor and thus mainly used for both folk medicine and vegetable. The stalks with apical buds are gathered in the early spring and planted in sandy soil or water in the greenhouse. The sprouting buds are then collected and sold as fresh vegetable. Although the plants have been used for food, they have been cultivated in a very small scale. In spring, local farmers just go around mountain areas to search the trees and gather the stalks as much as they get and sell them to the market. No conservation efforts have been made to stop the exploitation or to save the dwindling population. We tried to provide local farmers with the plants that may be used as an alternative to stalks from wild populations. This will bel! p conserve the wild populations. However, it is hard to propagate them either by conventional cuttings or by seed germination in a short period of time. Mass propagation using tissue culture systems have shown a great promise with several woody plants. Recently we developed a mass propagation technique via somatic embryogenesis system using mature and/or juvenile explants for Aralia elata. Several factors affecting somatic embryogenesis system including SE(somatic embryo) induction, embryogenic callus proliferation, SE germination, plant regeneration and transplanting to field frill be presented. And some problems arising for the somatic embryogenesis system will be also discussed.
Strain induced structural transformation, mechanical and phonon stability in silicene derived 2D-SiB
Manju M.S.,Siby Thomas,Anees P.,Sang Uck Lee,Ajith K. M. 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.90 No.-
Two-dimensional monolayer SiB is a silicene derivative exhibiting buckling of atoms similar to that seenin silicene. This manuscript presents a systematic study of the strain-dependent variation of thestructural, mechanical, and dynamical properties of SiB. Strain was applied in the uniaxial armchair,uniaxial zigzag, and biaxial directions within the range of0.2 to 0.3. The resultant strain energy plotindicates anisotropic behavior of SiB in these directions. The SiB showed a mechanical strength that washigher than its counterpart, silicene, by an order of 30%. The elastic constant data from the undeformedSiB indicated an anisotropic nature, which was also seen with all the strain directions. Charge densitycontours, along with Bader charge analysis, confirmed the ionic nature of SiB in its original form. Thisnature became covalent as the strain varied from the compressive to the tensile regime in the uniaxialzigzag and biaxial directions. The majorfinding described in this manuscript is a newflat conformationhaving orthorhombic symmetry in contrast to the buckled structure. In addition, this material wasobserved to attain stability with the application of uniaxial tensile armchair and zigzag directionalstrains. Ab-initio molecular dynamics simulation confirmed the thermal stability of SiB in its newconformation.
Regeneration and selection of root resistant Coleus forskohlii A threatened medicinal plant
George, Manju M.,Ssubramanian, R.B.,Prajapati, Hiren A. The Plant Resources Society of Korea 2001 Plant Resources Vol.4 No.2
Coleus forskohlii Briq, of the family Lamiaceae yields a valuable secondary metabolity known as forskolin which is a labdane diterpenoid.. Coleus forskohlii is the only known source of this compound. Forskolin is used in medicine for the treatment of glaucoma, congestive cardiomyopathy and asthma. Morphogenic callus was induced from young leaves on MS medium augmented with NAA and BA. These calli, when subcultured on MS with KN alone gave rise to shoots. The regenerated shoot developed good root system on MS medium fortified with NAA. The fully grown plantlets were transferred to soil for acclimatization. Coleus plant is mainly infected by a fungi Lasiodiplodia theobromae which causes root rot disease. The fungal culture filterate (ECE) of Lasiodiplodia theobromae, has been used in regeneration media to find the MIC and further to select resistant plants to the pathogen. In the present study 40% ECF in the medium showed maximum inhibition and is there fore considered as the MIC level of Coleus forshohlii. This data could prove to be useful for the future for selecting a resistant C.forskohlii plant against the root disease caused by L. theobromae.
Ju, H.Y.,Manju, M.D.,Kim, K.H.,Park, S.W.,Park, D.W. Korean Society of Industrial and Engineering Chemi 2008 Journal of industrial and engineering chemistry Vol.14 No.2
The synthesis of cyclic carbonate from butyl glycidyl ether (BGE) and carbon dioxide was performed in the presence of quaternary ammonium salt catalysts. Quaternary ammonium salts of different alkyl group (C<SUB>3</SUB>, C<SUB>4</SUB>, C<SUB>6</SUB> and C<SUB>8</SUB>) and anions (Cl<SUP>-</SUP>, Br<SUP>-</SUP> and I<SUP>-</SUP>) were used for this reaction carried out in a batch autoclave reactor at 60-120<SUP>o</SUP>C. The catalytic activity increased with increasing alkyl chain length in the order of C<SUB>3</SUB><C<SUB>4</SUB><C<SUB>6</SUB>. But, the quaternary ammonium salt with longer alkyl chain length (C<SUB>8</SUB>) decreased the conversion of BGE because it is too bulky to form an intermediate with BGE. For the counter anion of the tetrabutyl ammonium salt catalysts, the BGE conversion decreased in the order Cl<SUP>-</SUP>>Br<SUP>-</SUP>>I<SUP>-</SUP>. The effects of carbon dioxide pressure and reaction temperature on this reaction were also studied to better understand the reaction mechanism.
Karthi, N.,Karthiga, A.,Kalaiyarasu, T.,Stalin, A.,Manju, V.,Singh, S.K.,Cyril, R.,Lee, S.M. Pergamon 2017 Computational biology and chemistry Vol.70 No.-
<P>Pelargonidin is an anthocyanidin isolated from plant resources. It shows strong cytotoxicity toward various cancer cell lines, even though the carcinogenesis-modulating pathway of pelargonidin is not yet known. One of our previous reports showed that pelargonidin arrests the cell cycle and induces apoptosis in HT29 cells. Flowcytometry and immunoblot analysis confirmed that pelargonidin specifically inhibits the activation of CDK1 and blocks the G2-M transition of the cell cycle. In addition, DNA fragmentation was observed along with induction of cytochrome c release-mediated apoptosis. Hence, the aim of the present study was to investigate the molecular mechanism of pelargonidin's action on cell cycle regulators CDK1, CDK4, and CDK6 as well as the substrate-binding domain of DNMT1 and DNMT3A, which regulate the epigenetic signals related to DNA methylation. The results of docking analysis, binding free energy calculation, and molecular dynamics simulation correlated with the experimental results, and pelargonidin showed a specific interaction with CDK1. In this context, pelargonidin may also inhibit the recognition of DNA and catalytic binding by DNMT1 and DNMT3A. The HOMO-LUMO analysis mapped the functional groups of pelargonidin. Prediction of pharmacological descriptors suggested that pelargonidin can serve as a multitarget inhibitor for cancer treatment. (C) 2017 Elsevier Ltd. All rights reserved.</P>