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- 저자 : Li Yiru (검색결과 4 건)
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Valveless Piezoelectric Micropump of Parallel Double Chambers
Li Guo,Weiping Yan,Yinghua Xu,Yiru Chen 한국정밀공학회 2012 International Journal of Precision Engineering and Vol. No.
The driving performance of the piezoelectric actuator was simulated by ANSYS software, and the relationship between structure parameters and center displacement/frequency of piezoelectric actuator were obtained. The nozzle/diffuser pipes’structure parameters were optimized according to the results of ANSYS numerical simulation, and flow characteristic parameters such as flow rate and pressure distribution in the pipe were researched. The chamber was manufactured on glass, and nozzle/diffuser pipes were fabricated on <100> silicon by selective-wet etch using MEMS technology. These two components were glued with piezoelectric actuator together to form micropumps with single chamber and micropumps with parallel double chambers. The flow rates of micropumps in different conditions were measured by test system. Finally, a comparison between the test results of micropump with double chambers and that of the single chamber micropump is given.
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Kong Yiru,Li Jing,Liang Xiaohua,Zhou Xinli 한국유전학회 2023 Genes & Genomics Vol.45 No.9
Background Although numerous measures have been used to improve the outcome of lung cancer patients, lung cancer, as the second most common diagnosed cancer, is still the main cause of cancer death. It becomes increasingly urgent for us to deeply deplore the molecular mechanism of lung cancer and to discover the potential therapeutic targets. In our study, we are dedicated to discovering the role of MIB2 in lung cancer development. Methods The public databases were used to compare the expression level of MIB2 in cancer and non-cancer tissue. We analyzed the expression of MIB2 in lung cancer samples by performing Rt-PCR and western blot. We carried out CCK8 and clone assays to study the influence of MIB2 in lung cancer proliferation. The transwell assays and wound healing assays were implemented to study the function of MIB2 in metastasis and invasion. Proteins of cell cycle control pathways are detected to verify the potential mechanism of MIB2 in lung cancer progression. Results MIB2 is up regulated in lung cancer tissue compared to adjacent normal lung tissue according to both public databases and our clinical lung cancer samples. Knockdown of MIB2 inhibits proliferation, metastasis, and invasion of lung cancer cell lines. Cyclins and cyclin dependent kinases (CDK) including CDK2, CDK4, and cyclinB1 were down regulated in MIB2 knockdown cells. Conclusion Our results prove that MIB2 acts as a driver in NSCLC tumorigenesis by regulating cell cycle control pathways.
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Hu Changxiong,Li Yiru,Chen Guohua,Duan Pan,Wu Daohui,Liu Qing,Yin Honghui,Xu Tianyang,Zhang Xiaoming 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.3
Frankliniella occidentalis Pergrande is important invasive pests in China, causing damage to agricultural pro duction, and Orius similis Zheng is the dominant predator species of F. occidentalis. A two-year survey was conducted to determine the population density of F. occidentalis and O. similis, on chili (Capsicum annuum L.) and maize (Zea mays L.) crops and surrounding weed species, which included white clover (Trifolium repens L.), St. John’s wort (Hypericum beanii N. Robson), alfalfa (Medicago sativa L.) and beggarticks (Bidens pilosa L.) in Kunming, southern China. The activity of F. occidentalis on these 6 host plant species was determined using the quartile method. F. occidentalis mainly damaged plants during their flowering stage. The main activity period of F. occidentalis occurred earlier on H. beanii and T. repens than on C. annuum. The peak activity of F. occidentalis occurred in the middle of May (on T. repens). During the whole activity period, the highest thrips densities were recorded on H. beanii among all of the sampled host plant species, followed by C. annuum. The lowest density was recorded on B. pilosa. Dynamics of immature F. occidentalis were more irregular than that of adults. The highest density of O. similis was recorded on Z. mays. It was 2.27–26.43-fold (2017) and 2.01–19.09-fold (2018) higher than that on other host plant species. This study showed that F. occidentalis could migrate between C. annuum and surrounding weeds. The weeds were the main source of thrips on C. annuum. The results indicated that Z. mays can be planted around C. annuum fields as a potential banker plant, to attract O. similis to control F. occidentalis on C. annuum, T. repens and B. pilosa. The flowering period of plants and surrounding plant species has a great effect to the population activities of F. occidentalis and predator O. similis on crops.
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Hanjing Gao,Qing Song,Faqin Lv,Shan Wang,Yiru Wang,Xiaoyan Li,Yukun Luo,Xingguo Mei,Jie Tang 거트앤리버 소화기연관학회협의회 2017 Gut and Liver Vol.11 No.1
Background/Aims: This study investigated the protection provided by gabexate mesylate thermo-sensitive in-situ gel (GMTI) against grade III pancreatic trauma in rats. Methods: A grade III pancreatic trauma model with main pancreatic duct dividing was established, and the pancreas anatomical diagram, ascites, and serum biochemical indices, including amylase, lipase, C-reactive protein (CRP), interleukin 6 (IL- 6), and tumor necrosis factor-α (TNF-α), were examined. The pancreas was sliced and stained with hematoxylin eosin and subjected to terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining. Results: Ascites, serum amylase, lipase, CRP, IL-6, and TNF-α levels were significantly increased in the pancreas trauma (PT) groups with prolonged trauma time and were significantly decreased after GMTI treatment. The morphological structure of the pancreas was loose, the acinus was significantly damaged, the nuclei were irregular and hyperchromatic, and there was inflammatory cell invasion in the PT group compared to the control. After GMTI treatment, the morphological structure of the pancreas was restored, and the damaged acinus and inflammatory cell invasion were decreased compared to the PT group. Moreover, the cell apoptosis index was significantly increased in the PT group and restored to the same levels as the control group after GMTI treatment. Conclusions: GMTI, a novel formulation and drug delivery method, exhibited specific effective protection against PT with acute pancreatitis therapy and has potential value as a minimally invasive adjuvant therapy for PT with acute pancreatitis.
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