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- 저자 : Kin-yin Li (검색결과 3 건)
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Li Moses Man-Lung,Kwok Jojo Yan-Yan,Chung Kwong-Yin,Cheung Kin-Wing,Chiu Kwok-Hing,Chau Wai-Wang,Ho Kevin Ki Wai 대한슬관절학회 2020 대한슬관절학회지 Vol.32 No.-
Total knee arthroplasty (TKA) is associated with significant perioperative blood loss and postoperative allogenic blood transfusion. Tranexamic acid (TXA) reversibly blocks lysine binding sites on plasminogen molecules and inhibits plasmin formation. Comparisons of the efficacy and safety of intra-articular and intravenous TXA in primary TKA have not previously been reported.A prospective randomized trial was conducted in 150 patients who underwent TKA, and these patients were randomized into three groups. Patients in Group A were injected by intra-articular TXA according to body weight (20 mg/kg). Patients in Group B received a standard dose of intra-articular TXA (2000 mg), and those in Group C were infused with TXA according to body weight (20 mg/kg) before tourniquet deflation and again 3 h later. Baseline characteristics and data collected at blood transfusion were compared. Differences among four time points (baseline, day 0, day 2, and day 5) were carried out using ANOVA. The hemoglobin levels at postoperative day 5 were 10.6 g/dL for Group A, 10.6 g/dL for Group B, and 10.7 g/dL for Group C. The drain output was 399 ml for Group A, 314 ml for Group B, and 305 ml for Group C ( p = 0.03). Group C had significantly less drain output than Group A after post hoc comparisons ( p = 0.05), whereas no significant difference was observed between Group A and B ( p = 0.09) or between Group B and C. The weight-adjusted dose of TXA administered intravenously significantly reduced the drain output but not the total blood loss when compared with the weight-adjusted dose of TXA administered intra-articularly. No significant difference was observed in the other parameters among the three groups. The Joint CUHK-NTEC CREC, CRE-2013.644-T . Registered 1 March 2014.
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Illicit drug use is associated with lower bone mineral density and bone strength
Suhas Krishnamoorthy,Gloria Hoi-Yee Li,Kelvin Shun-Cheong Ho,Yin-Pan Chau,Constance Mak,Donna Ng,Albert Kar-Kin Chung,Jody Kwok-Pui Chu,Kathryn Choon-Beng Tan,Ruby Lai-Chong Hoo,Ching-Lung Cheung 대한골다공증학회 2023 Osteoporosis and Sarcopenia Vol.9 No.3
Objectives: To evaluate the association of illicit drug use with bone mineral density (BMD) and hip geometric parameters at the narrow neck. Methods: This is a cross-sectional matched cohort study conducted in the Hong Kong Chinese population. Associations with illicit drug use were estimated using linear regression for BMD (lumbar spine and femoral neck) and hip geometrical parameters (cross-sectional area [CSA], cross-sectional moment of inertia [CSMI], section modulus [SM], average cortical thickness [ACT] and BMD at the narrow neck) after adjusting for age, body mass index (BMI), smoking status, drinking status, physical activity, and history of antipsychotic and antidepressant use. Mean difference and 95% confidence intervals (95% CI) were calculated between 108 illicit drug users and 108 controls using an adjusted linear model and cluster-robust standard errors after matching by age and sex. The false discovery rate was used to correct for multiple testing. Results: Illicit drug users had a significantly lower BMD (g/cm2 ) at the lumbar spine (mean difference: -0.062; 95% CI: -0.108 to − 0.015), and femoral neck (mean difference: -0.058; 95% CI: -0.106 to − 0.010) in the fully adjusted model. Illicit drug users also had a significantly lower CSA (mean difference: -0.238 cm2 ; 95% CI: -0.462 to − 0.013), ACT (mean difference: -0.018 cm; 95% CI: -0.030 to − 0.006) and BMD (mean difference: -0.070 g/ cm2 ; 95% CI: -0.128 to − 0.012) at the narrow neck. Conclusions: Illicit drug use is associated with lower BMD and bone strength. Future studies evaluating the risk of illicit drug use with fragility fracture are warranted.
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Integration of Adults with Mental Handicaps into the Community of Hong Kong
David Ping-Pui,Tak-wah yeung,Man-hung Ngan,Chau-Kiu Cheung,Kin-yin Li BK21 Project Force of Special Education Deagu Univ 2001 Journal of Asia-Pacific Special Education Vol.1 No.3
The exten and factors of the integration of adults with mental handicaps into the community of Hong Kong is an uncharted area for rigorous investigation. To conduct the investigation, this study surveyed a representative sample of 692 adults, aged 15 or above, from the end of 1998 through early 1999. The survey sapmle sufficient numbers of adults of the three levels of handicaps, mild(n=234), moderate(n=337), and severe grades(n=121). To measure community intergration, the study employed a comprehensive set of scales, which demonstrated satisfactory reliability. With data weighted to best represent the population adults with mental handicaps in Hong Kong, the study found that being accepred was the highest.
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