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- 저자 : Khatereh Anbari (검색결과 2 건)
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khatereh Anbari,Koruosh Ghanadi,Alireza Toulabipour,Daryuosh Jamebozuorghi,Parastoo Baharvand 대한예방의학회 2023 예방의학회지 Vol.56 No.2
Objectives: Vaccination is an important intervention for preventing disease and reducing disease severity. Universal vaccination programs have significantly reduced the incidence of many dangerous diseases among children worldwide. This study investigated the side effects after immunization in infants under 1 year of age in Lorestan Province, western Iran.Methods: This descriptive analytical study included data from all children <1 year old in Lorestan Province, Iran who were vaccinated according to the national schedule in 2020 and had an adverse event following immunization (AEFI). Data were extracted from 1084 forms on age, sex, birth weight, type of birth, AEFI type, vaccine type, and time of vaccination. Descriptive statistics (frequency, percentage) were calculated, and the chi-square test and Fisher exact test were used to assess differences in AEFIs according to the abovelisted variables.Results: The most frequent AEFIs were high fever (n=386, 35.6%), mild local reaction (n=341, 31.5%), and swelling and pain (n=121, 11.2%). The least common AEFIs were encephalitis (n=1, 0.1%), convulsion (n=2, 0.2%), and nodules (n=3, 0.3%). Girls and boys only showed significant differences in mild local reactions (<i>p</i>=0.044) and skin allergies (<i>p</i>=0.002). The incidence of lymphadenitis (<i>p</i><0.001), severe local reaction (<i>p</i><0.001), mild local reaction (<i>p</i>=0.007), fainting (<i>p</i>=0.032), swelling and pain (<i>p</i>=0.006), high fever (<i>p</i>=0.005), and nodules (<i>p</i><0.001) showed significant differences based on age at vaccination.Conclusions: Immunization is a fundamental public health policy for controlling vaccine-preventable infectious diseases. Although vaccines such as the Bacillus Calmette-Guérin vaccine, oral poliovirus vaccine, and pentavalent vaccine are well-researched and reliable, AEFIs are inevitable.
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Mahshad Mousavi,Ahmad Khanifar,Nazanin Mousavi,Khatereh Anbari,Farzaneh Chehelcheraghi 대한성형외과학회 2022 Archives of Plastic Surgery Vol.49 No.3
Background Reactive oxygen species cause serious damage to the physiological function of tissues. Determination of total antioxidant capacity of skin tissue is one of the determinants of damaged tissue function.Mast cells (MCs) are one of the groups of cells that are invited to the site of injury. The healing process begins with the rapid release of various types of MCs’ intermediate factors at the site of injury. Bone marrow mesenchymal stem cell (BMMSC) production and secretion have been shown to regenerate the skin. The aim of this research was to evaluate the wound-healing and antioxidant effects of BMMSCs per MCs. Methods Fifty-four albino Wistar male rats were divided into three groups: (1) nonsurgery, (2) surgery, and (3) surgeryþBMMSCs. Groups 2 and 3 were operated with a 38 cmflap and in group 3, cell injections (7109 cell injection at the time of surgery) were performed. After days 4, 7, and 15, percentage of the surviving tissue, histological characteristics, superoxide dismutase (SOD) activity, and amount of malondialdehyde (MDA) were measured in the groups. For results, Graph Pad Prism 8 software was used, and data were analyzed and compared by analysis of variance and Tukey test. Results BMMSCs’ application decreased the amount of MDA, increased SOD activity and survival rate of the flaps, and improved the histological characteristics. Conclusion This study revealed the protective effects BMMSCs alongsideMCs against oxidative stress on the survival of the flaps. However, for clinical use, more research is needed to determine its benefits.
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