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      • KCI등재

        Dynamic three-dimensional shoulder kinematics in patients with massive rotator cuff tears: a comparison of patients with and without subscapularis tears

        Yuji Yamada,Yoshihiro Kai,Noriyuki Kida,Hitoshi Koda,Minoru Takeshima,Kenji Hoshi,Kazuyoshi Gamada,Toru Morihara 대한견주관절의학회 2022 대한견주관절의학회지 Vol.25 No.4

        Background: Massive rotator cuff tears (MRCTs) with subscapularis (SSC) tears cause severe shoulder dysfunction. In the present study, the influence of SSC tears on three-dimensional (3D) shoulder kinematics during scapular plane abduction in patients with MRCTs was examined. Methods: This study included 15 patients who were divided into two groups: supraspinatus (SSP) and infraspinatus (ISP) tears with SSC tear (torn SSC group: 10 shoulders) or without SSC tear (intact SSC group: 5 shoulders). Single-plane fluoroscopic images during scapular plane elevation and computed tomography (CT)-derived 3D bone models were matched to the fluoroscopic images using two-dimensional (2D)/3D registration techniques. Changes in 3D kinematic results were compared. Results: The humeral head center at the beginning of arm elevation was significantly higher in the torn SSC group than in the intact SSC group (1.8±3.4 ㎜ vs. −1.1±1.6 ㎜, p<0.05). In the torn SSC group, the center of the humeral head migrated superiorly, then significantly downward at 60° arm elevation (p<0.05). In the intact SSC group, significant difference was not observed in the superior-inferior translation of the humeral head between the elevation angles. Conclusions: In cases of MRCTs with a torn SSC, the center of the humeral head showed a superior translation at the initial phase of scapular plane abduction followed by inferior translation. These findings indicate the SSC muscle plays an important role in determining the dynamic stability of the glenohumeral joint in a superior-inferior direction in patients with MRCTs.

      • Endothelial progenitor cells promote astrogliosis following spinal cord injury through Jagged1-dependent Notch signaling.

        Kamei, Naosuke,Kwon, Sang-Mo,Ishikawa, Masakazu,Ii, Masaaki,Nakanishi, Kazuyoshi,Yamada, Kiyotaka,Hozumi, Katsuto,Kawamoto, Atsuhiko,Ochi, Mitsuo,Asahara, Takayuki M.A. Liebert 2012 JOURNAL OF NEUROTRAUMA - Vol.29 No.9

        <P>Interactions between endothelial and neural stem cells are believed to play a critical role in the kinetics of neural stem cells in the central nervous system. Here we demonstrate that endothelial progenitor cells promote the repair of injured spinal cord through the induction of Notch-dependent astrogliosis and vascular regulation. The transplantation of Jagged1(+/+) endothelial progenitor cells, but not Jagged1(-/-) endothelial progenitor cells, increased the number of reactive astrocytes during the acute phase, and improved functional recovery following spinal cord injury. Expression of the Notch effector Hes5 was upregulated in the injured spinal cord after Jagged1(+/+) endothelial progenitor cell transplantation. Furthermore, we found that the Notch ligand Delta-like-1 was highly expressed in Jagged1(-/-) endothelial progenitor cells. Transplantation of Delta-like-1, as well as Jagged1-overexpressing 3T3 cells, revealed that only Jagged1-overexpressing 3T3 stromal cells enhanced astrogliosis following spinal cord injury. In addition, Jagged1(+/+) endothelial progenitor cells exhibited not only dramatic pro-angiogenic effects, but also morphologically abnormal vessel stabilization, compared with Jagged1(-/-)endothelial progenitor cells in injured spinal cord. Thus, transplanted endothelial progenitor cells promote astrogliosis, vascular regulation, and spinal cord regeneration through activation of Jagged1-Notch signaling.</P>

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        Ho-doping Effect on the Incommensurate Magnetic Order in La1.88Sr0.12CuO4

        Masaki Fujita,Masanori Enoki,Kenji Tsutsumi,Satoshi Iikubo,Kazuyoshi Yamada 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.12

        We have performed elastic neutron scattering experiments on the superconductorLa1.85Ho0.03Sr0.12CuO4 to study the effect of substitution of a cation with a large magnetic momentat La site on the static spin correlation. In the Ho-free sample with a hole concentration of 0.12,the spatially-modulated magnetic order is known to be stabilized at temperature below Tspin 30K. In the present Ho-doped sample, we found the appearance of magnetic peaks at (0.5, 0.5 ± 0.119, 0) positions below Tspin 35 K, which is similar to the observation in the pristine sample. Furthermore, the volume-corrected intensities in the Ho-free and Ho-doped samples are comparable,suggesting a negligible effect of Ho-substitution at La sites. These results are quite a contrast tothe huge enhancement of the magnetic intensity and the increase of Tspin by substituting a comparableamounts of magnetic Fe3+ ions onto CuO2 planes. Therefore, the stability of the stripe orderinduced by the cation substitution is sensitive to the site at which the substitution occurs.

      • KCI등재

        High-energy Magnetic Excitations in Underdoped La1.90Sr0.10CuO4

        Kentaro Sato,Masato Matsuura,Masaki Fujita,Ryoichi Kajimoto,Sungdae Ji,Kazuhiko Ikeuchi,Mitsutaka Nakamura,Yasuhiro Inamura,Masatoshi Arai,Masanori Enoki,Kazuyoshi Yamada 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.12

        We measured the magnetic excitations in underdoped (UD) La1.90Sr0.10CuO4 by using inelasticneutron scattering over a wide energy range. We succeeded in observing the high-energy excitationsup to '160 meV. Hour-glass-like magnetic excitation, which is commonly seen in the superconductingphase of cuprate oxides, was confirmed. The Ecross (the energy where the dispersion is closestto the ( 12 , 12 ) reciprocal position) of 40 meV follows a linear relation between Ecross and the dopedhole concentration in the UD region. From the dispersion of high-energy excitations above Ecross,we successfully found an effective nearest neighbor interaction (Jeff ) of 102 ± 2 meV. This Jeff issmaller than the nearest neighbor interaction J(=132 meV) in the parent compound La2CuO4,indicating a reduction of Jeff by hole-doping.

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