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      • Extraction of GGO candidate regions from the LIDC database using deep learning

        Kazuki HIRAYAMA,Joo Kooi TAN,Hyoungseop KIM 제어로봇시스템학회 2016 제어로봇시스템학회 국제학술대회 논문집 Vol.2016 No.10

        In recent years, development of the computer-aided diagnosis (CAD) systems for the purpose of reducing the false positive on visual screening and improving accuracy of lesion detection has been advanced. Lung cancer is the leading cause of cancer death in the world. Among them, GGO (Ground Glass Opacity) that exhibited early in the before cancer lesion and carcinoma in situ shows a pale concentration, have been concerned about the possibility of undetected on the screening. In this paper, we propose an automatic extraction method of GGO candidate regions from the chest CT image. Our proposed image processing algorithms is consist of four main steps; 1) segmentation of volume of interest from the chest CT image and removing the blood vessel regions, bronchus regions based on 3D line filter, 2) first detection of GGO regions based on density and gradient which is selected the initial GGO candidate regions, 3) identification of the final GGO candidate regions based on DCNN (Deep Convolutional Neural Network) algorithms. Finally, we calculates the statistical features for reducing the false-positive (FP) shadow by the rule-based method, performs identification of the final GGO candidate regions by SVM (Support Vector Machine). Our proposed method performed on to the 31 cases of the LIDC (Lung Image Database Consortium) database, and final identification performance of TP: 93.02[%], FP: 128.52[/case] are obtained respectively.

      • Extraction of GGO Regions from Chest CT Images Using Deep Learning

        Kazuki HIRAYAMA,Noriaki MIYAKE,Huimin LU,Joo Kooi TAN,Hyoungseop KIM,Rie TACHIBANA,Yasushi HIRANO,Shoji KIDO 제어로봇시스템학회 2017 제어로봇시스템학회 국제학술대회 논문집 Vol.2017 No.10

        Lung cancer is the leading cause of death which accounts for the number of deaths in cancer in the world. Early detection and early treatment are regarded as an important. Especially, the ground glass opacity (GGO) is a shadow called pre-cancerous lesion, but it is a shadow which is difficult to detect by a radiologist because of haze and complicated shape. Therefore, in recent years, a computer aided diagnosis (CAD) system has been developed for the purpose of improving the detection accuracy for early detection and reducing the burden to radiologists. In this paper, we extract the GGO using Deep Convolutional Neural Network (DCNN) based on emphasized images. Before detect a GGO region, we apply preprocessing such as isotropic voxel to the original images, and extraction of the lung area. Next, we remove the vessel and bronchial region by 3D line filter based on Hessian matrix, and extract the initial candidate regions using density gradient, volume and sphericity. Subsequently, we segment the candidate regions, extraction of features, and reducing false positive shadows. Finally we create emphasize images and identify with DCNN using those images. As a result of applying the proposed method to 31 cases on Lung Image Database Consortium (LIDC), we obtained a true positive rate (TP) of 86.05 [%] and false positive number (FP) of 4.81 [/case].

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