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        Pharmacognostical Evaluation of Roots of Pygmaeopremna herbacea (Roxb.) Mold.

        Subha Rastogi,Madan Mohan Pandey,Kaushal Kumar,Ajay Kumar Singh Rawat,Palpu Pushpangadan 한국생약학회 2005 Natural Product Sciences Vol.11 No.2

        Pygmaeopremna herbacea (Roxb.) Mold. (Verbenaceae) is a small herb or sometimes an undershrub arising from a perennial rootstock. The dry roots are dark muddy brown in colour having root nodules. Itsextensively developed roots are widely used in tribal medicine. They are used as an aphrodisiac and for thetreatment of gout, rheumatism and ulcers. This study deals with the detailed pharmacognostical evaluation of thedried roots and root nodules of P. herbacea which includes macro and microscopic studies, determination ofphysicochemical parameters and chemoprofiling of the extract using HPTLC fingerprint profiles. It was observedthat the roots consist of a well developed cortical region consisting of tangentially elongated thin walledparenchymatous. The HPTLC fingerprint profile of the methanolic extract showed the presence of seven majorbands. Such an analysis may thus be utilized in identifying P. herbacea and in differenciating it from other specieswhich are similar to it or are used as its adultrants/substitutes under the same vernacular name of Bharangi.

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        Endoscopic Ultrasound-Guided Fine-Needle Aspiration of the Adrenal Glands: Analysis of 21 Patients

        Rajesh Puri,Ragesh Babu Thandassery,Narendra S. Choudhary,Hardik Kotecha,Smruti Ranjan Misra,Suraj Bhagat,Manish Paliwal,Kaushal Madan,Neeraj Saraf,Haimanti Sarin,Mridula Guleria,Randhir Sud 대한소화기내시경학회 2015 Clinical Endoscopy Vol.48 No.2

        Background/Aims: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) cytology of adrenal masses helps in etiological diagnosis. The aim of this study was to evaluate the diagnostic yield of EUS-FNA of adrenal masses in cases where other imaging methods failed and/or were not feasible. Methods: Twenty-one consecutive patients with adrenal masses, in whom adrenal FNA was performed because conventional imaging modalities failed and/or were not feasible, were prospectively evaluated over a period of 3 years. Results: Of the 21 patients (mean age, 56±12.2 years; male:female ratio, 2:1), 12 had pyrexia of unknown origin and the other nine underwent evaluation for metastasis. The median lesion size was 2.4×1.6 cm. Ten patients were diagnosed with tuberculosis (shown by the presence of caseating granulomas [n=10] and acid-fast bacilli [n=4]). Two patients had EUS-FNA results suggestive of histoplasmosis. The other patients had metastatic lung carcinoma (n=6), hepatocellular carcinoma (n=1), and adrenal lipoma (n=1) and adrenal myelolipoma (n=1). EUS results were not suggestive of any particular etiology. No procedure-related adverse events occurred. Conclusions: EUS-FNA is a safe and effective method for evaluating adrenal masses, and it yields diagnosis in cases where tissue diagnosis is impossible or has failed using conventional imaging modalities.

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