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박영수,김창오,김영근,홍성관,장경희,허애정,염준섭,송영구,김준명 대한감염학회 2001 감염 Vol.33 No.5
The Korean hemorrhagic fever (KHF) is an acute febrile disease with characteristic of fever, bleeding tendency, and renal failure. There are many complications of Korean hemorrhagic fever such as infection, anemia, internal bleeding, hypopituitarism, respiratory, and neurologic complication. A few cases were reported on acute pancreatitis with hemorrhagic fever abroad, but there was no case about Korean hemorrhagic fever with acute pancreatitis in this country. We experienced a case of Korean hemorrhagic fever associated with suspected acute pancreatits. With review of articles, we report a case of 51 year-old woman with KHF, where acute pancreatitis developed during management, (Korean J Infect Dis 33:376∼379, 2001)
Self-Assembly of Comb Copolymers
June Huh(허준) 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.1
The self-assembly behaviors of various comb copolymers are investigated by using Monte Carlo simulations, random phase approximation (RPA), and self-consistent field theoretic (SCFT) simulations. We consider three kinds of comb copolymer systems having different copolymer constitutions: comb copolymer with an alternating sequence of A and B side chains (a-CC); comb copolymer with blocky sequence of A and B side chains (b-CC); comb copolymer with side chains of A-B diblock chains (core-shell type side chain) (c-CC). A particular focus in this simulation study will be placed on the molecular packing of comb copolymers in their ordered structures, which will interpret various structural and transition characteristics in bulk and in thin films.
Supramolecular Assembly of End-Functionalized Polymer Mixtures Confined in Nanospheres
Huh, June,Jung, Ji Young,Lee, Jea Uk,Cho, Heesook,Park, Soojin,Park, Cheolmin,Jo, Won Ho American Chemical Society 2011 ACS NANO Vol.5 No.1
<P>Supramolecular assembly of functionalized polymers, capable of forming block copolymer-like molecular clusters, has emerged as a promising alternative for creating nanoscopically ordered structures. Here, we demonstrate that nanospheres, which have intriguing internal nanodomains and controllable surface functionality, can be fabricated by supramolecular assembly of two complementarily end-interacting species of mono-end-functionalized polymers using the self-organized precipitation (SORP) method. An exotic internal morphology, hierarchically organized structure of perforated spherical layers, was formed inside the nanosphere prepared from the stoichiometric mixture of the end-functionalized polymers, which is due to the formation of diblock-like supramolecules and their packing frustration in the spherically confined nanospace. When the mixing ratio of the two end-functionalized polymers differs from the stoichiometric ratio, the nanoparticle surface is enriched with an excess of unpaired functionalized groups, which therefore provides us with a useful way to precisely control the surface functionality of the nanoparticles.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2011/ancac3.2011.5.issue-1/nn101805z/production/images/medium/nn-2010-01805z_0003.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn101805z'>ACS Electronic Supporting Info</A></P>
Practical stepwise approach to rhythm disturbances in congenital heart diseases
Huh, June The Korean Pediatric Society 2010 Clinical and Experimental Pediatrics (CEP) Vol.53 No.6
Patients with congenital heart diseases (CHD) are confronted with early- and late-onset complications, such as conduction disorders, arrhythmias, myocardial dysfunction, altered coronary flow, and ischemia, throughout their lifetime despite successful hemodynamic and/or anatomical correction. Rhythm disturbance is a well-known and increasingly frequent cause of morbidity and mortality in patients with CHD. Predisposing factors to rhythm disturbances include underlying cardiac defects, hemodynamic changes as part of the natural history, surgical repair and related scarring, and residual hemodynamic abnormalities. Acquired factors such as aging, hypertension, diabetes, obesity, and others may also contribute to arrhythmogenesis in CHD. The first step in evaluating arrhythmias in CHD is to understand the complex anatomy and to find predisposing factors and hemodynamic abnormalities. A practical stepwise approach can lead to diagnosis and prompt appropriate interventions. Electrophysiological assessment and management should be done with integrated care of the underlying heart defects and hemodynamic abnormalities. Catheter ablation and arrhythmia surgery have been increasingly applied, showing increasing success rates with technological advancement despite complicated arrhythmia circuits in complex anatomy and the difficulty of access. Correction of residual hemodynamic abnormalities may be critical in the treatment of arrhythmia in patients with CHD.