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Antimalarial Effects of Areca catechu L.
Jiang, Jing-Hua,Jung, Suk-Yul,Kim, Youn-Chul,Shin, Sae-Ron,Yu, Seung-Taek,Park, Hyun The Physiological Society of Korean Medicine and T 2009 동의생리병리학회지 Vol.23 No.2
The emergence and spread of drug-resistant malaria parasites is a serious public health problem in the tropical world. Useful antimalarial drugs such as chloroquine have resistance in the world now. Moreover, other antimalarialdrugs such as mefloquine, halofantrine, atovaquone, proguanil, artemether and lumefantrine retain efficacy but have limitations, one of which is their high cost. New antimalarial drugs are clearly needed now. Cytotoxicity assay and susceptibility assay were performed for the selectivity of herb extracts in vitro. On the basis of high selectivity, 4-day suppressive test and survival test were progressed in Plasmodium berghei-infected mice. The selectivity of Areca catechu L. (ACL) and butanol extract of ACL (ACL-BuOH extract) were 3.4 and 3.0 in vitro, respectively. Moreover in vivo, 4-day suppressive test showed 39.1 % inhibition effect after treated with 150 mg/kg/day ACL-BuOH to P. berghei-infected mice. Survival test also showed 60% survival rate with ACL-BuOH-treated group while all other group mice died. In this study, ACL and ACL-BuOH were investigated for antimalarial activity in vitro and in vivo and they showed a potent antimalarial activity. In particular,ACL-BuOH could specifically lead higher survival rate of mice in vivo. Therefore ACL-BuOH would be a candidate of antimalarial drugs.
Anti-toxoplasmosis Effects of Oleuropein Isolated from <i>Fraxinus rhychophylla</i>
Jiang, Jing-Hua,Jin, Chun-Mei,Kim, Youn-Chul,Kim, Hun-Soo,Park, Won-Cheol,Park, Hyun Pharmaceutical Society of Japan 2008 Biological & pharmaceutical bulletin Vol.31 No.12
<P>Toxoplasmosis is a parasitic disease caused by <I>Toxoplasma gondii</I>, with very few therapeutic treatment options. Typically, the choices for treatment are pyrimethamine and sulfadiazine, however their utility is limited because of drug toxicity and serious side effects. For these reasons, new drugs with lower toxicity are urgently needed. In this study, the compound oleuropein isolated from <I>Fraxinus rhynchophylla</I> showed anti-<I>T. gondii</I> effects <I>in vitro</I> and <I>in vivo</I>. In Madin–Darby bovine kidney cells, the selectivity of oleuropein was 8.9, which was higher than sulfadiazine and pyrimethamine (3.8 and 2.5, respectively). In infected mice, the inhibition ratio of <I>T. gondii</I> in the peritoneal cavity was 55.4% compared to the negative control group after treatment with 300 mg/kg oleuropein. In addition, inhibitory effects on granuloma, apoptosis, necrosis and cyst-formation were shown in sections of spleen and liver. Oleuropein is therefore a potentially useful anti-<I>T. gondii</I> candidate for clinical application.</P>
Rapid Structural Improvement of CVD-Grown Multi-Walled Carbon Nanotubes by Drastic Thermite Reaction
Jiang Zhao,Jing Chen,Pengcheng Zhang,Haofeng Yu,Jie Chen 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.8
Multi-walled carbon nanotubes (MWCNTs) produced by chemical vapor deposition (CVD) are the most common commercial products at extremely low price in the market. However, due to the inherent drawbacks of CVD surroundings at temperature below ~ 1000℃, CVD-grown nanotubes usually have very disordered structure, resulting in most of their properties being much below expectations. Herein, we present a simple and energy-efficient method for improving rapidly the structure of CVD-grown MWCNTs via a drastic thermite reaction process. Direct observations from scan electron microscope (SEM) and transmission electron microscope (TEM) images, decrease of ID/IG ratios in Raman spectra, increase of the starting oxidation temperatures observed in thermogravimetric analysis (TGA), decrease of the volumetric electrical resistivity and decrease of the turn-on electric fields from 3.64 to 2.88 V/µm in field emission measurements suggest that the graphitization of MWCNTs can be effectively enhanced and the structure of nanotubes becomes more ordered after the drastic thermite reaction process.
Study of Spaceborne W-band Millimeter Wave Radiometer
Jing, Li,Shengwei, Zhang,Maohua, Sun,Decai, Kong,Heguang, Liu,Jingshan, Jiang 대한원격탐사학회 2001 International Symposium on Remote Sensing Vol.17 No.1
The W-band millimeter wave radiometer has been studied under the support of Chinese Academy of Science (CAS) and it is successfully studied for the first time in China. Its technical index is suitable for the use in space. The main characteristics of the W-band millimeter wave radiometer are introduced in this paper.
REMARKS ON FIXED POINT THEOREMS
Jiang, Guo-Jing,Kang, Shin-Min The Youngnam Mathematical Society Korea 2000 East Asian mathematical journal Vol.16 No.2
In this paper we show fixed point theorems related with the diameter of orbit on metric spaces. The results presented in this paper extend, improve and unify the results of $Heged\"{u}s$ [1], Kim, Kim, Leem and Ume [2], Kim and Leem [3], Ohta and Nikaido [4] and $Taskovi\'{c}$ [5].
Removal of Uranium from Aqueous Solution by Alginate Beads
Jing Yu,Jianlong Wang,Yizhou Jiang 한국원자력학회 2017 Nuclear Engineering and Technology Vol.49 No.3
The adsorption of uranium (VI) by calcium alginate beads was examined by batch experiments. The effects of environmental conditions on U (VI) adsorption were studied,including contact time, pH, initial concentration of U (VI), and temperature. The alginatebeads were characterized by using scanning electron microscopy, transmission electronmicroscopy, X-ray photoelectron spectroscopy, and Fourier transform infrared spectroscopy. Fourier transform infrared spectra indicated that hydroxyl and alkoxy groups arepresent at the surface of the beads. The experimental results showed that the adsorption ofU (VI) by alginate beads was strongly dependent on pH, the adsorption increased at pH 3~7,then decreased at pH 7~9. The adsorption reached equilibrium within 2 minutes. Theadsorption kinetics of U (VI) onto alginate beads can be described by a pseudo first-orderkinetic model. The adsorption isotherm can be described by the Redlich-Peterson model,and the maximum adsorption capacity was 237.15 mg/g. The sorption process is spontaneousand has an exothermic reaction.
SOME FIXED POINT THEOREMS FOR CONTRACTIVE AND EXPANSIVE MAPS
Jiang, Guo-Jing,Kang, Shin-Min Korean Mathematical Society 2002 대한수학회논문집 Vol.17 No.3
In this paper, axed point theorems for contractive and expansive maps are established, some of which extend a few results of Das and Debata, Edelstein, Fisher, Leader, Shih and Yeh, and Jungck.
Jing, Chen,Huang, Zhijie,Duan, Yuqin,Xiao, Xinrong,Zhang, Ru,Jiang, Jianqing Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2
Aim: An epidemiological study was conducted based on an esophageal cancer patient's cohort to investigate the association of folate intake and MTHFR C677T polymorphism with the prognosis of esophageal cancer in a Chinese population. Methods: 167 patients aged 37-75 years who had histological confirmed diagnosis of esophageal squamous cell cancer were collected from Jan. 2006 to Jan. 2008. MTHFR genotypes at the C677T site were analyzed by PCR-based RFLP methods, and the folate intake was computed by multiplying the food intake (in grams) and the folate content (per gram) of food in our questionnaire. Results: We found associations between the prognosis of esophageal cancer and smoking status, T and N stages. Individuals carrying the MTHFR 677CT and TT genotypes showed a shorter survival time than with the CC genotype, with adjusted HRs (95% CI) of 1.20 (0.56-2.15) and 2.29 (1.30-4.28), respectively. Similarly, those carrying MTHFR 677T allele had a 1.86-fold risk of death. A higher folate concentration showed a significant decreased risk of death, with an HR (95% CI) of 0.45 (0.18-0.87). Individuals with high folate intake and the MTHFR 677CC genotype showed a significant decreased risk of esophageal cancer (0.43, 0.25-0.89).Conclusion: Our findings supports the hypothesis that high folate intake and active MTHFR C677T polymorphism may exert protective roles in the prognosis of esophageal cancer in the Chinese population.
Does HBV Infection Increase Risk of Endometrial Carcinoma?
Jiang, Xue-Feng,Tang, Qiong-Lan,Zou, Yuan,Xu, Ling,Zeng, Hua,Chi, Cong,Jiang, Jing-Ru,Zhang, Bin-Zhong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2
Objective: Connections between chronic inflammation and tumor development and progression are now generally accepted. Recent evidence indicates that hepatitis B is associated with several types of cancer, but whether endometrial carcinoma (EC) is included has not been reported. Methods: We analyzed HBV serum marker status in 398 patients with endometrial cancer, comparing them to 788 control women undergoing health examination. Results: The total prevalence of HBsAg tested positive in cancer group was significantly higher than the control group (12.8% vs 6.0%, P=0.001), while positive HBsAb was significantly lower (41.2% vs 68.5%, P=0.001). Hepatitis B carriers in endometrial cancer group were also more frequent than in the control group (9.3% vs 5.5%, P=0.013). Interestingly, in the endometrial cancer group, 147 cases were HBV serum marker negative, which was also higher than in the control group (36.9% vs 15.6%, P=0.001). Conclusion: There may be a correlation between HBV infection and endometrial carcinoma.