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Irtiza, Syed,Samie, Amat Us,Ali, Shakir,Siddiqi, Mushtaq A,Naqash, Sameer H,Sameer, Aga Syed Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.5
The aim of this research was to investigate the possible association between gastric carcinoma (GC) and polymorphisms of the IL-$1{\beta}$ gene in the Kashmiri population using peripheral blood DNA from 150 gastric carcinoma cases and 250 population controls with detailed data for clinicopathological characteristics of the disease. Two SNPs in the IL-$1{\beta}$ gene were selected for this study. Expression of IL-$1{\beta}$ was studied in 50 gastric carcinoma cases using immunohistochemistry and RT-PCR and then correlated with genotype. The frequency of the IL-$1{\beta}$-511 C allele was significantly higher in the GC case group (53.3%) than in controls (45.4%) with an odds ratio (OR) of 0.73 and a P value of 0.03. Multivariate regression analysis showed associations of gastric carcinoma with mutant form of IL-$1{\beta}$-511 TT (OR 0.309; P value <0.001) and the CC genotype of IL-$1{\beta}$-31 (OR 0.313; P value of 0.002). Haplotype analysis of IL-$1{\beta}$-31 and IL-$1{\beta}$-511 showed decreased association of IL-$1{\beta}$-31 T with IL-$1{\beta}$-511 C with gastric carcinoma (OR 0.728; P value 0.03). Expression study of 50 samples by immunohistochemistry (IHC) and RT-PCR showed association with grade III and stage III+IV. After correlating the expression with polymorphism no association was found.
Manipulating the Sudden Death of Entanglement in Two-qubit Atomic Systems
Mahmood Irtiza Hussain,Rabia Tahira,Manzoor Ikram 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.41
We investigate the entanglement dynamics of a general two-qubit system in a noisy environment presenting analytical descriptions of the time evolution of entanglement having some unitary operations after its evolution in dissipative environments. We show that quantum gates (unitary operators) and bath switching can change the subsequent dynamics of entanglement. For this purpose, we consider σ_x and bath switching operations that change the disentanglement time from finite to infinite.
Adaptive Thresholding Technique for Segmentation and Juxtapleural Nodules Inclusion in Lung Segments
Muhammad Zia ur Rehman,Syed Omer Gilani,Syed Irtiza Ali Shah,Mohsin Jamil,Irfanullah,Shahid Ikramullah Butt 보안공학연구지원센터 2016 International Journal of Bio-Science and Bio-Techn Vol.8 No.5
Early diagnosis of lung cancer plays crucial role in the improvement of patients' chances of survival. Computer aided detection (CAD) system has been a groundbreaking step in the timely diagnosis and identification of potential nodules (lesions). CAD system starts detection process by extracting lung regions from CT scan images, this step narrows down the region for detection. Hence saving the time consumption and reducing false positives outside the lung regions that results in the improvement of specificity of system. Proper lung segmentation significantly increases the performance of CAD systems. Different algorithms are presented by various researchers to improve segmentation results. An intensity based approach is presented in this paper for the segmentation of parenchyma and the goal is to achieve reasonable segmentation results in less time. Algorithm used in this paper is based on the Intensity based thresholding which is the fastest method for image segmentation. Images used in this research to analyze algorithm's result are taken from Lung Image Database Consortium (LIDC). Twenty random cases were picked, each having different number of slices (128 to 300). Algorithm is implemented using MatlabR2014 and a system with processor of 2.6 GHz and RAM of 4 GB. Total time taken for a single case of 128 images was 6.3 seconds and hence with an average of 49 milli sec/slice.