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      • KCI등재후보

        Mitotane Therapy and Management of Naturally Occurring Pituitary Dependen Hyperadrenocorticism(PDH) in a Dog

        Jae-wonSong,Hee-MyungPark 한국임상수의학회 2003 한국임상수의학회지 Vol.20 No.2

        A 10 year old, intact female Yorkshire terrier was referred to the Veterinary Teaching Hospital of Konkuk University. Upon admission, the patient had severe necrotic skin disease on face and abdominal wall, and also showed polyuria, polydipsia (PUPD), and polyphagia. A tentatative diagnosis of hyperadrenocorticism was made on the basis of history takings, physical examination, and results of CBC and serum biochemistry. Hyperadrencorticism was confirmed by ACTH stimulation test and pituitary-dependent hyperadrenocorticism (PDH) was diagnosed according to the results of high dose dexamethasone suppression test (HDDST). After initiating mitotane therapy, severe skin problem and clinical signs including PUPD were improved. And we determined whether or not mitotane therapy well controlled serum cortisol level with ACTH stimulation test. This case was presented to show that the patient misdiagnosed and treated for more than 1 year as other dermatologic problems in 3 local animal clinics was treated and managed successfully with mitotane administration.

      • KCI등재후보

        A Case of Rodenticide Toxicosis in an English Sheepdog

        Ji-YunLee,ChulPark,Dong-InJung,Byung-HyunChung,Hee-MyungPark 한국임상수의학회 2003 한국임상수의학회지 Vol.20 No.2

        A spayed female English sheepdog, 4-year-old 18.2 kg, was referred to the Veterinary Teaching Hospital of Konkuk University due to the 4-day duration of epistaxis and dyspnea. Ingestion of anticoagulant rodenticides can inhibit the recycling of vitamin K1, which reduce the activity of circulating clotting factors. If immediate and appropriate treatment doesn't perform, it may result in depression or death through severe hemorrhage. This report present successful treatment of a 4-year-old spayed female dog with stupor and opisthotonos. Efficient treatment of whole blood transfusion and vitamin K1 improved clinical signs dramatically. The patient is recovered following treatment and healthy now.

      • KCI등재후보

        Oral Malignant Melanoma in a Labrador Retriever

        Ji-YunLee,Sang-YoenOh,Dae-YoungKim,ChulPark,Hun-YoungYoon,Soon-WukJeong,Hee-MyungPark 한국임상수의학회 2003 한국임상수의학회지 Vol.20 No.4

        A 12-year-old, intact male Labrador Retriever was admitted to the Veterinary Teaching Hospital of Konkuk University for the evaluation of bleeding mass in the oral cavity. The mass was first noted 2 years ago and has been growing up to a size of 5×6cm. On complete blood count(CBC), leukocytosis and mild anemia were observed. Pulmonary metastasis was found in the thoracic radiographic examination. Blackish necrotic oral mass at the left mandibular area was diagnosed as a malignant melanoma based on the histopathological examination. Thus hemimadi-bulectomy and chemotherapy (carboplatin) were performed. The patient eventually died due to severe secondary infection 3 months after the last treatment.

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