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      • SHAPE-SELECTIVE ISOPROPYLATION OF BIPHENYL OVER DEALUMINATED H-MORDENITES

        Sugi, Y,Kim, J.H,Matsuzaki, T,Hanaoka, T,Kubota, Y,Tu, X,Matusmoto, M 전남대학교 촉매연구소 1993 촉매학술발표회 Vol.- No.10

        Shape-selective alkylation using zeolitc is a useful way to introduce functional groups symmeetrically to aromatic hydrocarbons. One of important development on shape-selective catalysis achieved recently is the success in isopropylation of polynuclear aromatics, such as biphinyl and naphthalene over H-mordenite[1-5]. However, the mechanism of the catalysis related to solid acid sites and steric requirement in zeolite pores have not been fully understood. In this paper, we examine the isopropylation of biphenyland the ismerization of 4,4'-diisopropylbiphenyl over highly dealuminated H-mordenites, and discuss the mechanism of the catalysis.

      • KCI등재

        PRESSURE DEPENDENCE OF THE CURIE TEMPERATURE IN MnAlGe

        S. Endo,H. Matsuzaki,F. Ono,T. Kanomata,T. Kaneko 한국자기학회 1995 韓國磁氣學會誌 Vol.5 No.5

        The pressure dependence of the Curie temperature was determined in 2dimensional like ferromagnet, MnAlGe up to a maximum pressure of 7.5 ㎬ through measurements of electric resistance vs temperature curves. The pressure coefficient was positive with a considerably high rate of 9 K/㎬ in the low pressure ragion, while it decreased gradually down to one order of magnitude smaller value at the maximum pressure. It was concluded that ther is an upper limit of about 550 K in the super-exchange type ferromagnetic interaction between Mn layers.

      • Prediction of Blast Furnace Operation using On-line Bayesian Learning

        N.Kaneko,S.Sakamoto,K.Uchida,H.Ogai,M.Ito,S.Matsuzaki 제어로봇시스템학회 2008 제어로봇시스템학회 국제학술대회 논문집 Vol.2008 No.10

        The large scale database-based online modeling, called LOM, is a type of Just-In-Time modeling for blast furnace. In this paper, we propose a new type of LOM using a nonlinear local model to improve the performance of the long-term prediction. To estimate the parameter of the nonlinear local model, we use on-line Bayesian learning scheme with Sequential Monte Carlo. The prediction performance of the new LOM is demonstrated by using the real process data of blast furnace.

      • Age-Related Decline in Oligodendrogenesis Retards White Matter Repair in Mice

        Miyamoto, Nobukazu,Pham, Loc-Duyen D.,Hayakawa, Kazuhide,Matsuzaki, Toshinori,Seo, Ji Hae,Magnain, Caroline,Ayata, Cenk,Kim, Kyu-Won,Boas, David,Lo, Eng H.,Arai, Ken American Heart Association, Inc. 2013 Stroke Vol.44 No.9

        <P><B>Background and Purpose—</B></P><P>Aging is one of the major risk factors for white matter injury in cerebrovascular disease. However, the effects of age on the mechanisms of injury/repair in white matter remain to be fully elucidated. Here, we ask whether, compared with young brains, white matter regions in older brains may be more vulnerable in part because of decreased rates of compensatory oligodendrogenesis after injury.</P><P><B>Methods—</B></P><P>A mouse model of prolonged cerebral hypoperfusion was prepared by bilateral common carotid artery stenosis in 2-month and 8-month-old mice. Matching in vitro studies were performed by subjecting oligodendrocyte precursor cells to sublethal 7-day CoCl<SUB>2</SUB> treatment to induce chemical hypoxic stress.</P><P><B>Results—</B></P><P>Baseline myelin density in the corpus callosum was similar in 2-month and 8-month-old mice. But after induction of prolonged cerebral hypoperfusion, older mice showed more severe white matter injury together with worse deficits in working memory. The numbers of newborn oligodendrocytes and their precursors were increased by cerebral hypoperfusion in young mice, whereas these endogenous responses were significantly dampened in older mice. Defects in cyclic AMP response element-binding protein signaling may be involved because activating cyclic AMP response element-binding protein with the type-III phosphodiesterase inhibitor cilostazol in older mice restored the differentiation of oligodendrocyte precursor cells, alleviated myelin loss, and improved cognitive dysfunction during cerebral hypoperfusion. Cell culture systems confirmed that cilostazol promoted the differentiation of oligodendrocyte precursor cells.</P><P><B>Conclusions—</B></P><P>An age-related decline in cyclic AMP response element-binding protein–mediated oligodendrogenesis may compromise endogenous white matter repair mechanisms, and therefore, drugs that activate cyclic AMP response element-binding protein signaling provide a potential therapeutic approach for treating white matter injury in aging brains.</P>

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