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Preeti Kumari,Swati Sinha,Renuka Gahtori,Afshana Quadiri,Paras Mahale,Deepali Savargaonkar,Veena Pande,Bina Srivastava,Himmat Singh,Anupkumar R. Anvikar 대한기생충학ㆍ열대의학회 2022 The Korean Journal of Parasitology Vol.60 No.4
Malaria elimination and control require prompt and accurate diagnosis for treatment plan. Since microscopy and rapid diagnostic test (RDT) are not sensitive particularly for diagnosing low parasitemia, highly sensitive diagnostic tools are required for accurate treatment. Molecular diagnosis of malaria is commonly carried out by nested polymerase chain reaction (PCR) targeting 18S rRNA gene, while this technique involves long turnaround time and multiple steps leading to false positive results. To overcome these drawbacks, we compared highly sensitive cytochrome oxidase gene-based single-step multiplex reaction with 18S rRNA nested PCR. Cytochrome oxidase (cox) genes of P. falciparum (cox-III) and P. vivax (cox-I) were compared with 18S rRNA gene nested PCR and microscopy. Cox gene multiplex PCR was found to be highly specific and sensitive, enhancing the detection limit of mixed infections. Cox gene multiplex PCR showed a sensitivity of 100% and a specificity of 97%. This approach can be used as an alternative diagnostic method as it offers higher diagnostic performance and is amenable to high throughput scaling up for a larger sample size at low cost.
Avinash Vishwakarma,Sivaiah Bathula,Nagendra S. Chauhan,Ruchi Bhardwaj,Bhasker Gahtori,Avanish K. Srivastava,Ajay Dhar 한국물리학회 2018 Current Applied Physics Vol.18 No.12
SiGe alloy is widely used thermoelectric materials for high temperature thermoelectric generator applications. However, its high thermoelectric performance has been thus far realized only in alloys synthesized employing mechanical alloying techniques, which are time-consuming and employ several materials processing steps. In the current study, for the first time, we report an enhanced thermoelectric figure-of-merit (ZT)∼1.1 at 900 °C in ntype Si80Ge20 nano-alloys, synthesized using a facile and up-scalable methodology consisting of rapid solidification at high optimized cooling rate∼3.4×107 K/s, employing melt spinning followed by spark plasma sintering of the resulting nano-crystalline melt-spun ribbons. This enhancement in ZT>20% over its bulk counterpart, owes its origin to the nano-crystalline microstructure formed at high cooling rates, which results in crystallite size ∼7 nm leading to high density of grain boundaries, which scatter heat-carrying phonons. This abundant scattering resulted in a very low thermal conductivity ∼2.1 Wm−1K−1, which corresponds to ∼50% reduction over its bulk counterpart and is amongst the lowest reported thus far in n-type SiGe alloys. The synthesized samples were characterized using X-ray diffraction, scanning electron microscopy and transmission electron microscopy, based on which the enhancement in their thermoelectric performance has been discussed.
The effect of carbon nanotubes (CNT) on thermoelectric properties of lead telluride (PbTe) nanocubes
B. Khasimsaheb,Niraj Kumar Singh,Sivaiah Bathula,Bhasker Gahtori,D. Haranath,S. Neeleshwar 한국물리학회 2017 Current Applied Physics Vol.17 No.2
We report the thermoelectric properties of different weight percentage of carbon nano tubes (CNT) dispersed (0.025, 0.05 and 0.1%) in PbTe nanocubes matrix. The sample with 0.05% CNT distribution in the PbTe matrix significantly enhanced the electrical conductivity, and Seebeck coefficient above 450 K. In this system CNT’s acting as a low energy filter at potential barrier and good passage for high energy electron which may cause enhance the electrical conductivity. Mixing of CNT into PbTe nanocubes created numerous additional interfaces which are acted as scattering centers for phonons and thus resulted in ultra low thermal conductivity of 0.24 and 0.32 W/m K at 525 K for 0.025 and 0.05% CNT dispersed PbTe matrix, respectively. An optimum quantity of CNT addition to PbTe enhanced the zT ~0.11 at 525 K for both 0.025 and 0.05% CNT dispersed PbTe matrix, respectively, which is 90% higher in comparison to PbTe nanocubes. Finally, CNT’s dispersed PbTe nanocomposite exhibited good thermoelectric compatibility factor and these materials are good candidate materials for segmentation to get maximum power output during power generation applications.
High yield strength bulk Ti based bimodal ultrafine eutectic composites with enhanced plasticity
Misra, D. K.,Rakshit, R. K.,Singh, M.,Shukla, P. K.,Chaturvedi, K. M.,Sivaiah, B.,Gahtori, B.,Dhar, A.,Sohn, S. W.,Kim, W. T.,Kim, D. H. BUTTERWORTH - HEINEMANN 2014 MATERIALS AND DESIGN Vol.58 No.-
Ti-based bulk metallic glass (BMGs) and their bimodal composites are linked with the pronounced strain hardening after yielding but with much low value of strength. Therefore, developing Ti-based alloys with high yield strength and high plasticity is the current challenge. Here, we report the synthesis of ultra-fine grained bulk (UFG) (Ti0.705Fe0.295) 100 Ga-x(x) (0 <= x <= 2) bimodal eutectic composites with not only high strength and larger plasticity but also with high yield strength which is one of the important mechanical property for structural application. Reasonably high strength, high yield strength, strain to failure ratio, and enhanced plasticity of similar to 7 +/- 0.8% was observed in (Ti70.5Fe29.5)(98)Ga-2 composite which is superior than Ti-based BMGs and bimodal composites. Modification of degree of eutectic structure refinement and volume fraction of constituent phases with the addition of Ga are the crucial factors in enhancing the mechanical properties of Ti-Fi-(Ga) composites. (C) 2014 Elsevier Ltd. All rights reserved.