http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Deshpande Pruthviraj (검색결과 1 건)
- 무료
- 기관 내 무료
- 유료
-
Thappa Priya,Singh Nidhi,Luthra Ankur,Deshpande Pruthviraj,Chauhan Rajeev,Meena Shyam Charan,Kumar Vishal,Singla Navneet 대한척추외과학회 2023 Asian Spine Journal Vol.17 No.5
Study Design: Prospective randomized double-blind study.Purpose: To assess the analgesic effects of the combination of a low-dose ketamine and dexmedetomidine (ketodex) infusion and compare it with that of fentanyl for postoperative analgesia after spine surgeries.Overview of Literature: Adequate pain management following spine surgeries is crucial. Approximately 57% of patients experience inadequate pain control in the first 24 hours following elective spine surgery, which is attributable to the extensive soft tissue and muscle damage.Methods: The study included 60 patients graded American Society of Anesthesiologists I and II and scheduled for thoracolumbar spine surgery involving >3 vertebral levels. The patients were divided into two groups: group KD (ketodex) and group F (fentanyl). The primary objective was to compare the postoperative analgesic requirements among the groups. The secondary objectives included a comparison of the intraoperative anesthetic requirements, postoperative pain scores, hemodynamic parameters, side effects of the study drugs, and the duration of post-anesthesia care unit stay of both the groups.Results: Ketodex use prolonged the mean time to first rescue analgesia (22.00±2.30 hours vs. 11.69±3.02 hours, <i>p</i> <0.001) and reduced the requirement of rescue analgesics in the first 24 hours postoperatively compared to fentanyl use (70.00±8.16 μg vs. 113.31±36.65 μg, <i>p</i> =0.03). The intraoperative requirement of desflurane was comparable between the groups (<i>p</i> >0.05). The postoperative pain scores were significantly lower in the group KD than in group F at most timepoints (<i>p</i> <0.05). Patients in group KD had a shorter post-anesthesia care unit stay than group F did (<i>p</i> <0.001).Conclusions: Low-dose ketodex could be a safe substitute for fentanyl infusion when employed as an anesthetic adjuvant for patients undergoing thoracolumbar spine surgeries involving >3 vertebral levels to achieve prolonged analgesia without any opioidrelated side effects.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
