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RISS 인기검색어
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- 저자 : D. Frost (검색결과 5 건)
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Stefani Frost,Parisa Ziarati,Ryan Moen,Lynn Kysh,Robert Johnson,Shane Pearce,Siamak Daneshmand,Kimberly D. Siegmund,Victoria K. Cortessis 대한비뇨기종양학회 2024 대한비뇨기종양학회지 Vol.22 No.1
Purpose: Diabetes mellitus, a frequent comorbid condition in cancer patients, has been shown to increase risk of all-site cancer mortality. This relationship has not been systematically studied in bladder cancer patients. This systematic review and meta-analysis aimed to identify, evaluate, and synthesize available evidence on the relationship between history of diabetes and outcomes in bladder cancer patients. Materials and Methods: Systematic searches interrogated OVID MEDLINE, Embase, Web of Science, Google Scholar, and Cochrane Library to identify scholarly reports relating diabetes to all-cause mortality, bladder cancer-specific mortality, recurrence, and progression in bladder cancer patients. After critical review, metaanalysis was used to quantitively synthesize qualifying data and assess potential influence of publication bias, clinical heterogeneity, and residual confounding. Results: We synthesized data on over 226,472 patients treated with curative intent uniquely represented in 28 studies that met quality metrics. Having diabetes was positively associated with each outcome. Hazard ratio estimates were indistinguishable for mortality from any cause, 1.22 (95% confidence interval [CI], 1.12–1.33) and bladder cancer-specific mortality, 1.28 (95% CI 1.17–1.41) and notably stronger in patients with muscle-invasive and high-risk non–muscle-invasive bladder cancer, 1.32 (95% CI, 1.15–1.50) and 1.48 (95% CI, 1.06–2.06). Neither publication bias, systematic error, nor confounding by factors such as smoking or obesity is likely to explain the observed associations. Conclusions: Bladder cancer patients with diabetes experience elevated mortality that is not explained by diabetes-related comorbidities or complications. Future research should explore type, severity, and duration of diabetes in relation to unfavorable bladder cancer outcomes.
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Perspective: Theory and simulation of hybrid halide perovskites
Whalley, Lucy D.,Frost, Jarvist M.,Jung, Young-Kwang,Walsh, Aron American Institute of Physics 2017 The Journal of chemical physics Vol.146 No.22
<P>Organic-inorganic halide perovskites present a number of challenges for first-principles atomistic materials modeling. Such “plastic crystals” feature dynamic processes across multiple length and time scales. These include the following: (i) transport of slow ions and fast electrons; (ii) highly anharmonic lattice dynamics with short phonon lifetimes; (iii) local symmetry breaking of the average crystallographic space group; (iv) strong relativistic (spin-orbit coupling) effects on the electronic band structure; and (v) thermodynamic metastability and rapid chemical breakdown. These issues, which affect the operation of solar cells, are outlined in this perspective. We also discuss general guidelines for performing quantitative and predictive simulations of these materials, which are relevant to metal-organic frameworks and other hybrid semiconducting, dielectric and ferroelectric compounds.</P>
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Whalley, Lucy D.,Skelton, Jonathan M.,Frost, Jarvist M.,Walsh, Aron American Physical Society 2016 Physical Review B Vol.94 No.22
<P>Lattice vibrations in CH3NH3PbI3 are strongly interacting, with double-well instabilities present at the Brillouin zone boundary. Analysis within a first-principles lattice-dynamics framework reveals anharmonic potentials with short phonon quasiparticle lifetimes and mean free paths. The phonon behavior is distinct from the inorganic semiconductors GaAs and CdTe where three-phonon interaction strengths are three orders of magnitude smaller. The implications for the applications of hybrid halide perovskites arising from thermal conductivity, band-gap deformation, and charge-carrier scattering through electron-phonon coupling, are presented.</P>
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G. L. Hebeler,A. Martinez,J. D. Frost 대한토목학회 2016 KSCE Journal of Civil Engineering Vol.20 No.4
Interfaces, and the shearing of soil against them, play a crucial role in geotechnical engineering. As such, understanding the fundamental mechanisms of interface behavior, such as the size, shape, and extent of soil shear zones against geomaterial surfaces can lead to better understanding and design of geotechnical systems and testing methods. The current study presents a series of laboratory studies aimed at spatially quantifying shear zones created through soil – geomaterial interface shearing including mobilized interface strengths with a focus on CPT friction sleeve behavior. Parametric investigations of particle shape and size effects were carried out over a range of counterface surface roughness values. The results show that conventional “smooth” CPT friction sleeves induce solely particle sliding in coarse grained soils, while non-clogging textured friction sleeves can create a combination of particle shearing and sliding that can allow for direct interface measurements in-situ. By varying the amount of texture on an interface, the extent of particle shearing can be controlled, allowing for improved understanding and treatment of interfaces in geotechnical testing and design.
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L. Duenas-Osorio,박주남,P. Towashiraporn,B. J. Goodno,D. Frost,J. I. Craig,Ann Bostrom 국제구조공학회 2004 Structural Engineering and Mechanics, An Int'l Jou Vol.17 No.3-4
Consequence-Based Engineering (CBE) is a new paradigm proposed by the Mid-AmericaEarthquake Center (MAE) to guide evaluation and rehabilitation of building structures and networks inareas of low probability - high consequence earthquakes such as the central region of the U.S. Theprincipal objective of CBE is to minimize consequences by prescribing appropriate intervention proceduresfor a broad range of structures and systems, in consultation with key decision makers. One possibleintervention option for rehabilitating unreinforced masonry (URM) buildings, widely used for essentialfacilities in Mid-America, is pasive energy disipation (PED). After the CBE process is described, itsapplication in the rehabilitation of vulnerable URM building construction in Mid-America is illustratedthrough the use of PED devices attached to flexible timber floor diaphragms. It is shown that PEDs canbe applied to URM buildings in situations where flor diaphragm flexibility can be controlled to reduceboth out-of-plane and in-plane wall responses and damage. Reductions as high as 48% in rofdisplacement and acceleration can be achieved as demonstrated in studies reported below.
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