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      • KCI등재

        Role of Glutathione Redox System on the T-2 Toxin Tolerance of Pheasant (Phasianus colchicus)

        Csaba Fernye,Zsolt Ancsin,Andrea Bocsai,Krisztian Balogh,Miklos Mezes,Marta Erdelyi 한국독성학회 2018 Toxicological Research Vol.34 No.3

        The purpose of the present study was to evaluate the effects of different dietary concentrations of T-2 toxin on blood plasma protein content, lipid peroxidation and glutathione redox system of pheasant (Phasianus colchicus). A total of 320 one-day-old female pheasants were randomly assigned to four treatment groups fed with a diet contaminated with different concentrations of T-2 toxin (control, 4 ㎎/㎏, 8 ㎎/㎏ and 16 ㎎/㎏). Birds were sacrificed at early (12, 24 and 72 hr) and late (1, 2 and 3 weeks) stages of the experiment to demonstrate the effect of T-2 toxin on lipid peroxidation and glutathione redox status in different tissues. Feed refusal and impaired growth were observed with dose dependent manner. Lipid-peroxidation was not induced in the liver, while the glutathione redox system was activated partly in the liver, but primarily in the blood plasma. Glutathione peroxidase activity has changed parallel with reduced glutathione concentration in all tissues. Based on our results, pheasants seem to have higher tolerance to T-2 toxin than other avian species, and glutathione redox system might contribute in some extent to this higher tolerance, in particular against free-radical mediated oxidative damage of tissues, such as liver.

      • KCI등재

        Androgenesis induction in microspore culture of sweet pepper (Capsicum annuum L.)

        Csaba Lantos,Aniko´ Ge´mes Juhasz,Pa´l Va´gi,Ro´bert Miha´ly,Zolta´n Kristo´f,Ja´nos Pauk 한국식물생명공학회 2012 Plant biotechnology reports Vol.6 No.2

        Isolated microspore culture experiments were carried out in sweet pepper (Capsicum annuum L.) F1hybrid genotypes. In the first experiment, four culture media (W14, B5, MS and NLN) were compared to test their effectiveness in inducing the formation of microsporederived structures in two genotypes. The experiments revealed the superiority of B5 medium. In the second experiment, the effects of different ratios of 2,4-dichlorophenoxyacetic acid (2,4-D) (0, 0.1, 0.2 and 0.5 mg l-1) and kinetin (0, 0.2 and 0.5 mg l-1) were also investigated in B5medium with two genotypes. The effect of growth regulators were investigated on the production of microsporederived calli and embryo-like structures (ELSs), the ratio of the two and plant regeneration (number of regenerated plantlets) in microspore culture. The histological experiments revealed the differences between the microsporederived ELSs and calli. The most promising results were obtained on the investigated parameters in the presence of 0.1 mg l-1 2,4-D and 0.2 mg l-1 kinetin producing the highest number of plantlets in both genotypes tested. In the response of 11 genotypes, the androgenesis induction was successful in each sweet pepper genotypes tested using the best basic medium and growth regulators combination. In case of 11 genotypes, the number of ELSs ranged from 20 to 100/Petri dish (an average of 48.1 ELS/Petri dish),while the number of green plantlets varied from 0 to 8plantlets/Petri dish (an average of 1.5 plantlets/Petri dish)depending on the genotype. The spontaneous rediploidization rate obtained was 25% in isolated microspore.

      • KCI등재
      • KCI등재

        Following-up changes in red blood cell deformability and membrane stability in the presence of PTFE graft implanted into the femoral artery in a canine model

        Csaba Toth,Ferenc Kiss,Zoltan Klarik,Eszter Gergely,Eniko Toth,Katalin Peto,Erzsebet Vanyolos,Iren Miko,Norbert Nemeth 한국유변학회 2014 Korea-Australia rheology journal Vol.26 No.2

        It is known that a moderate mechanical stress can even improve the red blood cells’ (RBC) micro-rheologicalcharacteristics, however, a more significant stress causes deterioration in the deformability. In thisstudy, we aimed to investigate the effect of the presence of artificial graft on the RBC deformability andmembrane stability in beagles. In the Control group only anesthesia was induced and in the postoperative(p.o.) period blood samplings were carried out. In the Grafted group under general anesthesia, the leftfemoral artery was isolated, from which a 3.5 cm segment was resected and a PTFE graft (O.D.: 3 mm)of equal in length was implanted into the gap. On the 1st, 3rd, 5th, 7th and 14th p.o. days blood was collectedthe cephalic veins and RBC deformability was determined ektacytometry (LoRRca MaxSis Osmoscan). Membrane stability test consisted of two deformability measurements before and after the cells werebeing exposed to mechanical stress (60 or 100 Pa for 300 seconds). Compared to the Control group andthe baseline values the red blood cell deformability showed significant deterioration on the 3rd, 5th andmainly on the 7th postoperative day after the graft implantation. The membrane stability of erythrocyterevealed marked inter-group difference on the 3rd, 5th and 7th day: in the Grafted group the deformabilitydecreased and during the membrane stability test smaller difference was observed between the statesbefore and after shearing. We concluded that the presence of a PTFE graft in the femoral artery maycause changes in RBC deformability in the first p.o. week. RBC membrane stability investigation showsa lower elongation index profile for the grafted group and a narrowed alteration in the deformabilitycurves due to mechanical stress.

      • KCI등재

        Silicon Nitride Composites with Different Nanocarbon Additives

        Csaba Balázsi 한국세라믹학회 2012 한국세라믹학회지 Vol.49 No.4

        This paper explores the use of a variety of carbon nanoparticles to impart electrical, thermal conductivity, good frictional properties to silicon nitride matrices. We used the highly promising types of carbon as carbon nanotubes, exfoliated graphene and carbon black nanograins. A high-efficiency attritor mill has also been used for proper dispersion of second phases in the matrix. The sintered silicon nitride composites retained the mechanical robustness of the original systems. Bending strength as high as 700 MPa was maintained and an electrical conductivity of 10 S/m was achieved in the case of 3 wt% multiwall carbon nanotube addition. Electrically conductive silicon nitride ceramics were realized by using carbon nanophases. Examples of these systems, methods of fabrication, electrical percolation, mechanical, thermal and tribological properties are discussed.

      • KCI등재

        Role of glutathione redox system on the susceptibility to deoxynivalenol of pheasant (Phasianus colchicus)

        Csaba Fernye,Zsolt Ancsin,Márta Erdélyi,Miklós Mézes,Krisztián Balogh 한국독성학회 2020 Toxicological Research Vol.36 No.2

        There are only a few reports on the effects of mycotoxins on pheasant (Phasianus colchicus) and the susceptibility to deoxynivalenol of these birds have never been reported before. The present experiment focuses to investigate the effects of different dietary concentrations of deoxynivalenol on blood plasma protein content, some parameters of lipid peroxidation and glutathione redox system and on the performance of pheasant chicks. A total of 320 1-day-old female pheasants were randomly assigned to four treatment groups fed with a diet contaminated with deoxynivalenol (control, 5.11 mg/kg, 11.68 mg/kg and 16.89 mg/kg). Birds were sacrificed at early (12, 24 and 72 h) and late (1, 2 and 3 weeks) stages of the experiment to demonstrate the oxidative stress-inducing effect of deoxynivalenol. Feed refusal was dose dependent, especially in the last third of the trial, but only minor body weight gain decrease was found. Lipid-peroxidation parameters did not show dose-dependent effect, except in blood plasma during the early stage of the trial. The glutathione redox system, reduced glutathione content and glutathione peroxidase activity, was activated in the liver, but primarily in the blood plasma. Glutathione peroxidase activity has changed parallel with reduced glutathione concentration in all tissues. Comparing our results with literature data, pheasants seem to have the same or higher tolerance to deoxynivalenol than other avian species, and glutathione redox system might contribute in some extent to this tolerance, as effective antioxidant defence against oxidative stress.

      • KCI등재

        CAD and FEM Modelling of Theoretical Roughness in Diamond Burnishing

        Csaba Felhö,Gyula Varga 한국정밀공학회 2022 International Journal of Precision Engineering and Vol.23 No.4

        Diamond burnishing is a widely used finishing machining that can have a positive effect on both the roughness of cut surfaces and its stress state. This paper is focused on the examination of the theoretical and real roughness of surfaces machined by sliding burnishing. In determining the theoretical roughness, the surface structure created by the pre-burnishing cutting (turning) was also considered. Two different modelling methods were used to obtain theoretical surface roughness data: CAD-modelling and finite element simulation. A method using CAD-based modelling of the machined surface was used to determine the theoretical roughness for both the turning and burnishing processes. However, this previously developed model is not directly applicable to plastic deformation processes such as diamond burnishing, so the principle of the Hertz theory for normal contact of elastic solids was used to calculate the penetration depth of the tool into the workpiece. The 2D FEM simulations were performed in the DEFORM software. To validate the applied modelling methods, real cutting experiments were performed, where the surface roughness values were measured during diamond burnishing experiments with different feed per revolution values. Based on the comparison of both applied modelling methods with real roughness data it can be stated that the theoretical roughness values are well approximated the real data.

      • KCI등재

        Rise and Fall of Beer Lovers’ Parties in East Central Europe: Party History and General Lessons

        Csaba Fazekas 한국외국어대학교(글로벌캠퍼스) 러시아연구소 2021 REGION Vol.10 No.2

        This article deals with the process of how beer drinking became a factor in party organization in East Central European politics in the 1990s. It presents historical data on party formation in several nations (Ukraine, Russia, Czecho- slovakia, Poland, and Hungary) as well as campaign activity and results. The characteristics and history of beer lovers’ parties are not simply illustrations of postcommunist party systems. Party organizers saw beer drinking as convey- ing a complex and coherent message that would attract members and follow- ers: friendly beer drinking suggests a peaceful political climate; beer brewing is closely connected to manufacturing, agriculture, and the hospitality industry; it is also a starting point for environmental protection. They found that while beer is indeed a complex symbol, it was not enough to sustain a successful party. And yet an exploration of the theoretical underpinnings of beer parties, and of these parties’ birth and eventual demise, provides valuable insights into both the region and the early postcommunist era.

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