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      • Biomediated Silver Nanoparticles for the Highly Selective Copper(II) Ion Sensor Applications

        Kirubaharan, C. Joseph,Kalpana, D.,Lee, Yang Soo,Kim, A. R.,Yoo, Don Jin,Nahm, Kee Suk,Kumar, G. Gnana American Chemical Society 2012 INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH - Vol.51 No.21

        <P>Nanoparticles synthesis is an evergreen research field of 21st century in which the connotation of the biomediated experimental process is highly imperative. Biomediated silver nanoparticles were synthesized with the aid of an eco-friendly biomaterial, namely, aqueous <I>Azadirachta indica</I> extract. The effect of pH and temperature on the formation of silver nanoparticles was analyzed. Formation of the silver nanoparticles was verified by surface plasmon spectra using a UV–vis spectrophotometer. Morphology and crystalline structure of the prepared silver nanoparticles were characterized by TEM and XRD techniques, respectively. Furthermore, the biomediated silver nanoparticles without any surface modification were used for the heavy metal ion sensors in aqueous media. The prepared silver nanoparticles were successful in detecting even the minimal amount of heavy metal copper(II) ion and exhibited excellent specific metal ion selectivity.</P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ie3003232'>ACS Electronic Supporting Info</A></P>

      • KCI등재후보
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        Modulatory Effects of Curcumin and Curcumin Analog on Circulatory Lipid Profiles During Nicotine-Induced Toxicity in Wistar Rats

        Venugopal P. Menon,K.N. Rajasekharan,C. Kalpana 한국식품영양과학회 2005 Journal of medicinal food Vol.8 No.2

        Nicotine, a major toxic component of cigarette smoke, plays a key role in the development of cardiovascular disease and lung cancer. In the present study, we have synthesized an analog of curcumin and biomonitored its influence over biochemical marker enzymes and lipid profiles on nicotine-induced toxicity in Wistar rats. The effects were compared with that of curcumin, a well-known antioxidant and anti-hyperlipidemic agent. Toxicity was induced by subcutaneous injection of nicotine at a dose of 2.5 mg/kg of body weight (5 days a week, for 22 weeks), and curcumin (80 mg/kg) was given simultaneously along with nicotine by intragastric intubation for 22 weeks. Measurements of activities of the biochemical marker enzymes aspartate transaminase, alanine transaminase, alkaline phosphatase, and lactate dehydrogenase and of plasma lipid profiles were used to monitor the anti-hyperlipidemic effects of curcuminoids. In nicotine-treated rats, enhanced plasma marker enzymes and lipid profiles were observed. Administration of curcumin or curcumin analog to nicotine-treated rats significantly reduced the activity of marker enzymes and plasma lipid levels. Thus, our findings suggest that curcumin and its analog exert an anti-hyperlipidemic effect against nicotine-induced lung toxicity and may be a promising agent for treatment of hyperlipidemia and atherosclerosis

      • KCI등재후보

        Evolution of a Productive Bivoltine Hybrid of Silkworm Bombyx mori L.(SD7${\times}$SD12) with Shorter Larval Duration

        Rao, P.Sudhakara,Basavaraja, H.K.,Kalpana, G.V.,Naik, V.Nishitha,Mahalingappa, K.C.,Pallavi, S.N. Korean Society of Sericultural Science 2004 International Journal of Industrial Entomology Vol.8 No.1

        With an objective of evolving quantitatively and qualitatively superior bivolitine silkworm hybrid of Bombyxmori L. for tropics with shorter larval duration without compromising on productivity traits, a breeding programme was initiated at this institute during 1997 by utilizing breeding resource material from the institutes Germplasm collection. The breed SD7 is characterized with plain larvae spinning white oval cocoons and SD12 is characterized by sex-limited larval markings spinning white dumb-bell cocoons. After fixation, these breeds along with other newly evolved breeds were subjected for hybrid evaluation in the laboratory. Based on the hybrid studies, the hybrid SD7${\times}$SD12 was selected and evaluated for one year comprising three major sea- sons (6 trials) of tropics viz., Pre-monsoon (characterized by high temperature, low humidity and without any rain fall), Monsoon (characterized by moderate temperature, heavy rain fall with high humidity) and post-monsoon season (characterized by low temperature and low humidity with frequent rain fall) to know the fluctuations in the larval duration. The evaluation studies indicated that the hybrid is having shorter larval duration with productive merits. The hybrid SD7${\times}$SD12 recorded survival percent of 92.74, shell weight of 46.7 cg, shell ratio % of 24.0 and filament length of 1,200 meters with a shorter larval duration of 24 hrs; when compared to productive hybrid CSR2${\times}$CSR5(control). The breeding methodologies and hybrids usefulness for tropics were discussed.

      • KCI등재후보

        Evolution of a Productive Bivoltine Hybrid of Silkworm Bombyx mori L. (SD7 x SD12) with Shorter Larval duration

        P. Sudhakara Rao,H. K. Basavaraja,G. V. Kalpana,V. Nishitha Naik,K. C. Mahalingappa,S. N. Pallavi 한국잠사학회 2004 International Journal of Industrial Entomology Vol.8 No.1

        With an objective of evolving quantitatively and qualitatively superior bivoltine silkworm hybrid of Bombyx mori L. for tropics with shorter larval duration without compromising on productivity traits, a breeding programme was initiated at this institute during 1997 by utilizing breeding resource material from the institutes Germplasm collection. The breed SD7 is characterized with plain larvae spinning white oval cocoons and SD12 is characterized by sex-limited larval markings spinning white dumb-bell cocoons. After fixation, these breeds along with other newly evolved breeds were subjected for hybrid evaluation in the laboratory. Based on the hybrid studies, the hybrid SD7 ´ SD12 was selected and evaluated for one year comprising three major seasons (6 trials) of tropics viz., Pre-monsoon (characterized by high temperature, low humidity and without any rain fall), Monsoon (characterized by moderate temperature, heavy rain fall with high humidity) and post-monsoon season (characterized by low temperature and low humidity with frequent rain fall) to know the fluctuations in the larval duration. The evaluation studies indicated that the hybrid is having shorter larval duration with productive merits. The hybrid SD7 ´ SD12 recorded survival percent of 92.74, shell weight of 46.7 cg, shell ratio % of 24.0 and filament length of 1,200 meters with a shorter larval duration of 24 hrs; when compared to productive hybrid CSR2 ´ CSR5 (control). The breeding methodologies and hybrids usefulness for tropics were discussed.

      • KCI등재후보

        Evolution of a Productive Bivoltine Hybrid of Silkworm Bombyx mori L. (SD7×SD12) with Shorter Larval Duration

        ( P. Sudhakara Rao ),( H. K. Basavaraja ),( G. V. Kalpana ),( V. Nishitha Naik ),( K. C. Mahalingappa ),( S. N. Pallavi ) 한국잠사학회 2007 International Journal of Industrial Entomology Vol.8 No.1

        With an objective of evolving quantitatively and qualitatively superior bivolitine silkworm hybrid of Bombyx mori L. for tropics with shorter larval duration without compromising on productivity traits, a breeding programme was initiated at this institute during 1997 by utilizing breeding resource material from the institutes Germplasm collection. The breed SD7 is characterized with plain larvae spinning white oval cocoons and SD12 is characterized by sex-limited larval markings spinning white dumb-bell cocoons. After fixation, these breeds along with other newly evolved breeds were subjected for hybrid evaluation in the laboratory. Based on the hybrid studies, the hybrid SD7×SD12 was selected and evaluated for one year comprising three major seasons (6 trials) of tropics viz., Pre-monsoon (characterized by high temperature, low humidity and without any rain fall), Monsoon (characterized by moderate temperature, heavy rain fall with high humidity) and post-monsoon season (characterized by low temperature and low humidity with frequent rain fall) to know the fluctuations in the larval duration. The evaluation studies indicated that the hybrid is having shorter larval duration with productive merits. The hybrid SD7×SD12 recorded survival percent of 92.74, shell weight of 46.7 cg, shell ratio % of 24.0 and filament length of 1,200 meters with a shorter larval duration of 24 hrs; when compared to productive hybrid CSR2×CSR5 (control). The breeding methodologies and hybrids usefulness for tropics were discussed.

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