광중합형 글라스아이오노머 시멘트와 복합레진의 전단결합강도에 관한 연구

김덕,민병순 大韓齒科保存學會 1994 Restorative Dentistry & Endodontics Vol.19 No.2

아르곤 레이저에 의한 복합레진의 중합시 물성 변화에 관한 연구

김덕,민병순,최호영,최기운,박상진 大韓齒科保存學會 1998 Restorative Dentistry & Endodontics Vol.23 No.1

After polymerizing composite resin with argon laser and visible light, four test, to be concretelv, measurement of compressive strength using Instron testing machine, surface microhardness using Rockwell hardness tester, quantitative analysis of residual monomer using HPLC and analysis of degree of conversion using FTIR, were accomplished. Test groups were a sort of specimen with 3mm diameter, 4㎜ thickness for measuring compressive strength, two sort of specimen with 7mm diameter, 2mm and 3㎜ thickness for measuring surface microhardness, quantitative analysing of residual monomer after curing and measuring the degree of conversion, each were divided by according to the condition of light exposure. In case of argon laser. in 1.0W and 0.5W output. the exposure time for specimen were 5 sec, 10 sec respectiyely. In case of visible light, the exposure time obtained. 1. Compressive strength of composite resin was the highest in the group of 1W output, exposing for 10 sec with argon laser, followed by the group of 0.5W, exposing for 10 sec with argon laser, the group of exposing for 40 sec with visible light. But there were statistically no significant difference between these three groups(p>0.05). 2. Surface microhardness of composite resin wasn't significantly affected by light curing conditions. 3. BIS- GMA within residual monomer was least detected in the group of exposing for 40 sec. TEGDMA was least detected in the group of 1W output, exposing for 10 sec with argon laseboth 2㎜ and 3㎜ thickness specimen. 4. The degree of conversion of all groups in the 2㎜ thickness specimen were more than 5%, similar to each other but in the group of 1W, exposing 10 sec with argon laser the degree of conversion was highest in the 3㎜ thickness specimen. 5. Argon laser could make composite resin to has similar properties with 25% lesser exposure time than visible light.

휠체어 검도 경기를 위한 경기규정에 관한 연구

김영학,공병덕,이병기 龍仁大學校 武道硏究所 2002 武道硏究所誌 Vol.13 No.1

The purpose of this study was to build revised game rules for wheelchair Kumdo for the physically challenged confined to wheelchair, after teaching 10 people how to play Wheelchair Kumdo. It's ultimately intended to determine whether or not the revised game regulations were appropriate and workable and ultimately to promote Wheelchair Kumdo. There Kumdo trainees of the 4th, 5th and 6th grades respectively and three physically different people were coached to draft game rules in three phases, and they were finalized through an advice of a specialist. And then five disabled Kumdo trainees, who included three of the 3rd grade and two of the 2nd grade, learned the regulations for a month to find out their adequacy. As a result of interviewing them and analysing the collected data, the following findings were given: First, the stadium should have a flat floor, by using proper materials such as wood or concrete, to guarantee the smooth operation of wheelchair. It should be in a square form and 11 meter or higher in length. The starting lines should bo marked 'T' on both sides from the central line, and the upper parts of the marks should face each other. There should be 1.7m distance between the central and starting lines and 2 meter or higher extra spaces in the external sides. Second, the bamboo sword should be redesigned to be 114cm in length and 370g in weight to fit in wheelchair Kumdo. Third, among Kumdo equipment, Homyun(護面, Headgear), part of HoKu(Protection-equipment, 護具), should be made of lighter materials, thicker in the head part, and easy to wear. Gab(甲, Chest-guard) should have a sort of shock absorber in it, and a remodeled Hoku that has no wings on both sides should be used. To prevent wheelchair from shock and ensure its safety, a Quickie All Court model should be selected, and each contestant should wear a suit of different color that has his or her name on the shoulder portion. Fourth, each game should run four minutes, constituted by two periods, and a break time should be given. The judgment should be made without no extra time, and a contestant who hits one of the due points ahead of the other should be a winner. Fifth, as for Yuhyo-Geokja(有效擊刺, Point), action against the head, wrist or waist should be considered Geokja(擊刺, Strike), and one against the chest part should be regarded as Jabu(刺部, Stab). Based on the above-mentioned findings, there are some suggestions about wheelchair Kumdo games: First, as games could be held out in the field, outdoor programs should be attempted. Second, every game is divided into the first and second periods, and coaches need to develop programs suitable for the two-part competition to give better guidance. Third, general Kumdo equipment isn't suitable for wheelchair Kumdo, and a lot of research efforts should urgently be dedicated to developing separate equipment for that.

광중합형 글라스아이오노머 시멘트와 복합레진과의 전단결합강도에 관한 연구

김덕,민병순,최호영,박상진,최기운 慶熙大學校 齒科大學 1994 慶熙齒大論文集 Vol.16 No.1

The purpose of this study is to evaluate of shear bond strength of light-curing composite resin to light-curing glass ionomer cement. Composite resin and glass ionomer cement have been widely used as an esthetic filling materials in dental clinics. To achieve better clinical results, sandwich technic was developed with conpensating for disadvantages of these two materials. Especially, light-curing glass ionomer cement provided greately improved bonding strength of teeth or composite resin, and then excellent clinical results can be acquired. In this study, 6 commercial light-curing glass ionomer cements(3 commercial restorative materials Fuji II LC, Vanglass VLC, Vitremer, and 3 commercial lining materials : Fuji Lining LC, Baseline VLC, Vitrebond) were devided two groups. According to manufacturer's appointment, no surface treatment was referred to N groups. Supposing of clinical practice, surface grinding with water ;spray at 320 grit sand paper, 40 seconds etching with 37% phosphoric acid, 20 seconds washing 20 seconds air drying was referred to E groups. Totally 12 experimental groups were devided, and all 120 specimens from 10 specimens of each groups were made. After light-curing composite resin was bonded to right-curing glass ionomer cement, shear bond strength was tested by Instron universal testing machine between glass ionomer cement and composit resin. The data were analyzed statistically by Student's t-test and ANOVA. The obtained results were as follows; 1. In light-curing glass ionomer cement, restorative materials showed higher shear bond strength to composite resin than lining matenals(p<0.05). 2. Variglass VLC of restorative material group and Baseline VLC of lining material group have highest shear bond strength to composite resin(p<0.001). 3. In light-curing glass ionomer cement:, surface grinding and acid etching reduced shear bond strengthto composite resin(p<0.001). 4. VGN group is highest shear bond strength to composite resin, VBE group is lowest shear bond strength to composite resin(p<0.001).

Polylysine을 입힌 배양면이 GH₃ 뇌하수체 종양 세포에 미치는 영향에 관한 연구

김정진,백상호,황덕호,황영일,이왕재,이병란 대한해부학회 1998 Anatomy & Cell Biology Vol.31 No.3

Simple Sequence Repeat Primer에 의한 딸기의 Genomic DNA 분석

양덕춘,최성민,김무성,민병훈 경희대학교 생명자원과학연구원 2002 硏究論文集 Vol.22 No.-

본 연구는 진핵세포에 널리 산재되어있는 repeat sequence를 primer로 사용하여 딸기의repeat sequence 좌위를 증폭시켜서 분석하고 이를 같은 종일지라도 지역간의 차이로 인한 환경의 변화 또는 재배방법의 차이에 의해서 일어나는 변이를 분석하는 방법에 활용할 수 있도록 하기 위하여 수행하였다. GGC repeat sequence의 딸기 genomic DNA에 존재여부를 판명하기 위하여 (GGC)_(6) probe를 DIG을 사용하여 labeling하여 딸기 genomic DNA에 hybridization한 결과 확실한 spot이 나타났다. 또한 repeat sequence로 이루어진 UBC SSR primer 100개중에서 4가지 서로 다른 primer에서 선명한 band를 확인할 수 있어서 딸기의 genomic DNA내에 여러 종류의 repeat sequence가 있는 것으로 판단되었다. 따라서 각 품종별 표지로서 이용성을 알아보고자 PCR을 수행하였는 바 (ACC)_(6)와 (CCG)_(6)의 primer에서는 다른 band에 비해 매우 확실한 밴드를 형성하였다 이러한 PCR product의 염기서열분석을 위해 우선 대량증식을 위한 PCR의 적정 조건은 primer 10p㏖, DNA 50ng으로서 수행하는 것이 DNA의 증폭에 좋았다. 증폭된 1 Kb DNA 절편을 이용하여 염기서열을 조사하였던 바, 808bp의 서열을 알아냈고 그 반복염기서열은 효모와 사람에 존재하는 유전자이었으며 Cdontella sinensis와의 유의성 검정결과 ACC 반복염기에 62% 동일성을 나타내었다. This study was carried out to investigate genetic variation caused by environmental change or cultural method difference, which was performed by amplifying repeat sequence loci of strawberry widely dispersed in eukaryotic cell. DIG labeled(GGC)_(6), probe was used to test if GGC repeat sequence exists in strawberry genomic DNA, resulting in clear spot on the filter. Among the 100 UBC SSR primers which contain repeat sequence, four different primers amplified clear DNA fragments, suggesting that the repeat sequence exist in the genome of strawberry. PCR was also performed to test whether these primers could be used for a marker among strawberry cultivars. (ACC)_(6), (No. 861) and (CCG)_(6) (No. 865) primers showed very clear bands compared to the other primers. The amplified 808 bp of 1 kb DNA was sequenced, and database search using the sequence information showed that the repeat sequence was the gene existed both in yeast and human, and a significant sequence homology to Odontella sinensis was found.

<i>Ixeris dentata</i> NAKAI Reduces Clinical Score and HIF-1 Expression in Experimental Colitis in Mice

Kim, Dae-Seung,Ko, Jang-Ho,Jeon, Yong-Deok,Han, Yo-Han,Kim, Hyun-Ju,Poudel, Amrit,Jung, Hyun-Ju,Ku, Sae-Kwang,Kim, Su-Jin,Park, Sang-Hyun,Park, Jin-Han,Choi, Byung-Min,Park, Sung-Joo,Um, Jae-Young,Hon Hindawi Publishing Corporation 2013 Evidence-based Complementary and Alternative Medic Vol.2013 No.-

<P><I>Ixeris dentata</I> (ID) is an herbal medicine used in Asian countries to treat indigestion, pneumonia, hepatitis, contusions, and tumors; however, its effect on intestinal inflammation is unknown. Thus, we investigated the effect of ID in the dextran sulfate sodium (DSS) model of colitis in female BALB/c mice; animals were evaluated after seven days of DSS treatment. DSS-treated mice showed considerable clinical signs, including weight loss, reduced colon length, colonic epithelial injury, infiltration of inflammatory cells in the colon tissue, and upregulation of inflammatory mediators. However, administration of ID attenuated body weight loss, colon shortening, and the increase in disease activity index score. ID also significantly decreased the colonic mucosal injury and the number of infiltrating mast cells. Moreover, ID inhibited the expressions of cyclooxygenase-2 and hypoxia-inducible factor-1<I><I>α</I></I> in colon tissue. Taken together, the results provide experimental evidence that ID might be a useful therapy for patients with ulcerative colitis.</P>

Long-Term Prognosis for Chronic Hepatitis C: Clinical Follow-Up after Achieving and Non-Achieving Sustained Virologic Response with Peginterferon Plus Ribavirin Combination Therapy

( Deok Yeong Kim ),( Jae Ho Park ),( Myung Hee Kim ),( Min Seong Kim ),( Min Kyung Back ),( Byung Seok Lee ),( Eaum Seok Lee ),( Hyuk Soo Eun ),( Jong Seok Joo ),( Woo Sun Rou ),( Seok Hyun Kim ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: Peg-interferon and ribavirin combination therapy was once the treatment standard for patients with chronic hepatitis C and is an option that is still used today. Its ultimate goal is to achieve a sustained viral response (SVR). Several studies have shown about 42 to 82% SVR with less than 1% relapse rate. However, there are not many cases of SVR of HCV in Korea, and also there is no definite study on SVR maintenance and observation period. Aim of this study was to evaluate the achievement rate and the prognosis of patients with achievement of SVR or not during the period of 5 years for peg-interferon and ribavirin combination therapy. Methods: 94 patients successfully treated with peg-interferon and ribavirin combination therapy Patients with HCV genotype 1 (34 patients, 36.2%) at a constant dose received treatment for 48 weeks, whereas non-1 genotype patient (60 patients, 63.8%) received treatment for 24 weeks. The ratio of each achievement and non-achievement of SVR and the incidence rate of liver cirrhosis as well as HCC for each patients during 5- year follow-up periods were evaluated. Results: Among the whole patients, 86 patients (86/94, 80.8%) achieved SVR. However, relapse of HCV RNA occurred in 4 patients (4/86, 4.7%), including two patients with persistent viremia (2/86, 2.3%). The SVR rates of genotype 1 and non-1 genotype were 70.6% (24/34) and 91.7% (55/60), respectively. All of the 8 patients (8/94, 8.5%) who did not achieve SVR had persistent viremia and 7 patients (7/8, 87.5%) were genotype 1 and rest of the patients were genotype IIa. Six patients (6/8. 75%) with genotype 1 progressed to cirrhosis and four of them (4/8, 50%) progressed to HCC. Conclusions: Our results suggest that HCV patients who did not reached SVR, have a high risk for liver cirrhosis or HCC. However, although there are not many cases, our study showed that the risk of liver cirrhosis or HCC is still present in case of non-genotype I, even if SVR is reached. Therefore, longterm outpatient follow-up is recommended for patients chronic hepatitis C, and appropriate treatment and management are required for relapse.

Postoperative Flat Back : Contribution of Posterior Accessed Lumbar Interbody Fusion and Spinopelvic Parameters

Kim, Jin Kwon,Moon, Byung Gwan,Kim, Deok Ryeng,Kim, Joo Seung The Korean Neurosurgical Society 2014 Journal of Korean neurosurgical society Vol.56 No.4

Objective : Posterior accessed lumbar interbody fusion (PALIF) has a clear objective to restore disc height and spinal alignment but surgeons may occasionally face the converse situation and lose lumbar lordosis. We analyzed retrospective data for factors contributing to a postoperative flat back. Methods : A total of 105 patients who underwent PALIF for spondylolisthesis and stenosis were enrolled. The patients were divided according to surgical type [posterior lumbar inter body fusion (PLIF) vs. unilateral transforaminal lumbar interbody fusion (TLIF)], number of levels (single vs. multiple), and diagnosis (spondylolisthesis vs. stenosis). We measured perioperative index level lordosis, lumbar lordosis, pelvic tilt, sacral slope, pelvic incidence, and disc height in standing lateral radiographs. The change and variance in each parameter and comparative group were analyzed with the paired and Student t-test (p<0.05), correlation coefficient, and regression analysis. Results : A significant perioperative reduction was observed in index-level lordosis following TLIF at the single level and in patients with spondylolisthesis (p=0.002, p=0.005). Pelvic tilt and sacral slope were significantly restored following PLIF multilevel surgery (p=0.009, p=0.003). Sacral slope variance was highly sensitive to perioperative variance of index level lordosis in high sacral sloped pelvis. Perioperative variance of index level lordosis was positively correlated with disc height variance ($R^2=0.286$, p=0.0005). Conclusion : Unilateral TLIF has the potential to cause postoperative flat back. PLIF is more reliable than unilateral TLIF to restore spinopelvic parameters following multilevel surgery and spondylolisthesis. A high sacral sloped pelvis is more vulnerable to PALIF in terms of a postoperative flat back.

A “Nanoprism” Probe for Nano-optical Applications

Kim, Taekyeong,Kim, Deok-Soo,Lee, Byung Yang,Kim, Zee Hwan,Hong, Seunghun WILEY-VCH Verlag 2009 ADVANCED MATERIALS Vol.21 No.12

<B>Graphic Abstract</B> <P>“Nanoprism” probes are fabricated for nano-optical applications. The fabrication process is scalable for mass-production, and can be used to prepare nanoprobes terminated with virtually any nanostructure, such as nanoprisms, ZnO nanorods, and nanoparticles. ANSOM imaging was performed on a nanoparticle using Au-nanoprism probes, revealing field localization at the vertices of the nanoprism. <img src='wiley_img/09359648-2009-21-12-ADMA200801528-content.gif' alt='wiley_img/09359648-2009-21-12-ADMA200801528-content'> </P>