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이정민,Christoph J Zech,Luigi Bolondi,Eduard Jonas,김명진,Osamu Matsui,Elmar M. Merkle,Michiie Sakamoto,최병인 대한영상의학회 2011 Korean Journal of Radiology Vol.12 No.4
This paper reports on issues relating to the optimal use of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid magnetic resonance imaging (Gd-EOB-DTPA MR imaging) together with the generation of consensus statements from a working group meeting, which was held in Seoul, Korea (2010). Gd-EOB-DTPA has been shown to improve the detection and characterization of liver lesions, and the information provided by the hepatobiliary phase is proving particularly useful in differential diagnoses and in the characterization of small lesions (around 1-1.5 cm). Discussion also focused on advances in the role of organic anion-transporting polypeptide 8 (OATP8) transporters. Gd-EOB-DTPA is also emerging as a promising tool for functional analysis, enabling the calculation of post-surgical liver function in the remaining segments. Updates to current algorithms were also discussed.
Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma
Abou-Alfa, Ghassan K.,Meyer, Tim,Cheng, Ann-Lii,El-Khoueiry, Anthony B.,Rimassa, Lorenza,Ryoo, Baek-Yeol,Cicin, Irfan,Merle, Philippe,Chen, YenHsun,Park, Joong-Won,Blanc, Jean-Frederic,Bolondi, Luigi New England Journal of Medicine 2018 The New England journal of medicine Vol.379 No.1
<P>Among patients with previously treated advanced hepatocellular carcinoma, treatment with cabozantinib resulted in longer overall survival and progression-free survival than placebo. The rate of high-grade adverse events in the cabozantinib group was approximately twice that observed in the placebo group.</P>