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        A prospective study of fully covered self-expandable metal stents for refractory benign pancreatic duct strictures

        Bhavik Bharat Shah,Gajanan Ashokrao Rodge,Usha Goenka,Shivaraj Afzalpurkar,Mahesh Kumar Goenka 대한소화기내시경학회 2022 Clinical Endoscopy Vol.55 No.6

        Background/Aims: Fully covered self-expanding metal stents (FCSEMSs) are a relatively novel option for treating painful main pan-creatic duct refractory strictures in patients with chronic pancreatitis. Herein, we aimed to assess the efficacy, feasibility, and safety ofFCSEMSs in this patient group. Methods: This prospective single-center study included patients who underwent endoscopic retrograde pancreatography withFCSEMS placement. The primary endpoints were the technical and clinical success rates. A reduction in visual analog scale pain scoreof >50% compared with that before stent placement was defined as clinical success. Secondary endpoints were resolution of pancreaticstrictures on fluoroscopy during endoscopic retrograde pancreatography and the development of stent-related adverse events. Results: Thirty-six patients were included in the analysis. The technical success rate was 100% (n=36) and the clinical success rate was86.1% (n=31). There was a significant increase in stricture diameter from 1.7 mm to 3.5 mm (p<0.001) after stent removal. The meanvisual analog scale pain score showed statistically significant improvement. At 19 months of follow-up, 55.6% of the patients were as-ymptomatic. Stent migration (16.7%), intolerable abdominal pain (8.3%), development of de novo strictures (8.3%), and mild pancre-atitis (2.8%) were the most common adverse events. Conclusions: FCSEMS placement showed good technical and clinical success rates for achieving pain relief in patients with refractorymain pancreatic duct strictures.

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        Mucosal Changes in the Small Intestines in Portal Hypertension: First Study Using the Pillcam SB3 Capsule Endoscopy System

        Mahesh Kumar Goenka,Bhavik Bharat Shah,Vijay Kumar Rai,Surabhi Jajodia,Usha Goenka 대한소화기내시경학회 2018 Clinical Endoscopy Vol.51 No.6

        Background/Aims: To evaluate patients with portal hypertension (PH) of varied etiologies for portal hypertensive enteropathy (PHE)using the PillCam SB3 capsule endoscopy (CE) system. Methods: Consecutive patients with PH presenting with unexplained anemia and/or occult gastrointestinal bleeding were evaluatedusing the PillCam SB3 CE system. Abnormal findings were categorized as vascular or non-vascular. The patients with ongoing bleedingcaused by PHE were treated. The correlation of the CE scores of PHE with the clinical, laboratory, and endoscopic features wasdetermined. Results: Of the 43 patients included in the study, 41 (95.3%) showed PHE findings. These included varices (67.4%), red spots (60.5%),erythema (44.2%), villous edema (46.5%), telangiectasia (16.3%), and polyps (16.3%). The CE scores varied from 0 to 8 (mean±standarddeviation, 4.09±1.8). Five patients (11.6%) showed evidence of ongoing or recent bleeding due to PHE. Three of these five patientsunderwent endotherapy, and one patient underwent radiological coil placement. Conclusions: The PillCam SB3 CE system revealed a high prevalence of PHE in the patients with PH. Using this system, evidence ofbleeding due to PHE was found in a small but definite proportion of the patients.

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