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Mohammadzadeh, Soleiman,Baghi, Narmin,Yousefi, Fayegh,Yousefzamani, Bahar The Korean Pediatric Society 2019 Clinical and Experimental Pediatrics (CEP) Vol.62 No.9
Background: Attention deficit-hyperactivity disorder (ADHD) is one of the most common chronic behavioral disorders in school-aged children. Purpose: This study aimed to evaluate the effect of omega-3 supplementation as an alternative therapy for ADHD, which can be caused by vitamin and mineral deficiencies. Methods: This was a double-blinded clinical trial study. Sixty-six children with ADHD (aged 6-12 years) referred to our child and adolescent psychiatric educational and therapeutic clinic were selected based on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision criteria. Instruments including the Parent ADHD Rating Scale were used to assess ADHD at 0, 2, 4, and 8 weeks during the study. Results: The results showed no statistically significant difference between the methylphenidate with omega-3 group and methylphenidate with placebo group based on the Parents ADHD Rating Scale between week 0 ($P{\geq}0.96$) and week 8 ($P{\geq}0.75$). There were no significant intergroup differences between the Inattention ($P{\geq}0.48$) and hyperactivity/impulsivity ($P{\geq}0.80$) subscale scores on the Parents ADHD Rating Scale. The most common drug complications in the methylphenidate with placebo and methylphenidate with omega-3 groups were anorexia (27 [54%] vs. 41 [60.29%], respectively) and diarrhea (10 [20%] vs. 8 [11.76%], respectively), but the differences were not statistically significant (P>0.05). Conclusion: Our results demonstrate that a specific dose of omega-3 for 8 weeks had no effect on ADHD.
Optimal Control of Steel Structures by Improved Particle Swarm
Saeid Aghajanian,Hadi Baghi,Fereidoun Amini,Masoud Zabihi Samani 한국강구조학회 2014 International Journal of Steel Structures Vol.14 No.2
Active control is one of the modern approaches in seismic design of steel structures. Recently, induced by economicconsiderations, especially high expenses of control systems, optimality has become an important issue. In this paper an activesystem is used to control a steel structure’s displacements by a simplified pole assignment method. To optimize the number,the locations, and the total driving force of the required actuators, an improved particle swarm algorithm is presented focusingon the parameters of the velocity equation. A Geographical neighborhood topology and an adaptive inertia weight are used toimprove the standard PSO algorithm. In addition to the local and global best solutions, the positions of the best particles inthe geographical neighborhood are mathematically represented in an additional term. The performance of the proposedalgorithm is compared with the traditional Genetic Algorithm (GA) and the standard particle swarm considering the optimalcontrol of a 12-story steel structure as a numerical example. High capabilities of the proposed method in terms of the controltarget, convergence rate, and accuracy are simultaneously clarified by the results.
Soleiman Mohammadzadeh,Narmin Baghi,Fayegh Yousefi,Bahar Yousefzamani 대한소아청소년과학회 2019 Clinical and Experimental Pediatrics (CEP) Vol.62 No.9
Background: Attention deficit-hyperactivity disorder (ADHD) is one of the most common chronic behavioral disorders in school-aged children. Purpose: This study aimed to evaluate the effect of omega-3 supplementation as an alternative therapy for ADHD, which can be caused by vitamin and mineral deficiencies. Methods: This was a double-blinded clinical trial study. Sixty-six children with ADHD (aged 6–12 years) referred to our child and adolescent psychiatric educational and therapeutic clinic were selected based on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision criteria. Instruments including the Parent ADHD Rating Scale were used to assess ADHD at 0, 2, 4, and 8 weeks during the study. Results: The results showed no statistically significant difference between the methylphenidate with omega-3 group and methylphenidate with placebo group based on the Parents ADHD Rating Scale between week 0 (P≥0.96) and week 8 (P≥0.75). There were no significant intergroup differences between the Inattention (P≥0.48) and hyperactivity/impulsivity (P≥0.80) subscale scores on the Parents ADHD Rating Scale. The most common drug complications in the methylphenidate with placebo and methylphenidate with omega-3 groups were anorexia (27 [54%] vs. 41 [60.29%], respectively) and diarrhea (10 [20%] vs. 8 [11.76%], respectively), but the differences were not statistically significant (P> 0.05). Conclusion: Our results demonstrate that a specific dose of omega-3 for 8 weeks had no effect on ADHD.
Bacteriophages: cancer diagnosis, treatment, and future prospects
Abbaszadeh Faezeh,Leylabadlo Hamed Ebrahimzadeh,Alinezhad Farbod,Feizi Hadi,Mobed Ahmad,Baghbanijavid Shabnam,Baghi Hossein Bannazadeh 한국약제학회 2021 Journal of Pharmaceutical Investigation Vol.51 No.1
Background Early diagnosis is one of the most important factors in cancer treatment. Unfortunately, despite remarkable advances in the diagnosis and treatment methods of cancers in recent years, these methods are far from being perfect and have significant limitations and disadvantages. High costs and unwanted damage to healthy cells are some of the most important challenges. Area covered With the advent of novel technologies, potentially advantageous methods are being studied actively. The use of bacteriophages is one of the modern methods for cancer diagnosis and treatment. In the present article, we will discuss the potential advantages and limitations regarding the use of bacteriophages in the diagnosis and treatment of malignancies. Expert opinion The use of bacteriophages is one of the more recent methods for cancer diagnosis and treatment. Due to the non-pathogenic nature of bacteriophages, their genetic engineering capability makes them a great option for therapeutic purposes. The exact potential of phages to be used in the diagnosis and treatment of cancer, will be determined with further research in the future.