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        Prevalence of Sleep Disturbances During COVID-19 Pandemic in a Nepalese Population: A Cross-Sectional Study

        Avinash Chandra,Pooja Prakash,Nabina Sharma,Ayush Chandra 대한수면연구학회 2021 Journal of sleep medicine Vol.18 No.3

        Objectives: The coronavirus disease (COVID-19) pandemic and news of daily increasing cases inside Nepal and worldwide is adding to the fear that leads to anger, anxiety, frustration, and stress, emotions that directly affect sleep quality. This study aimed to assess sleep disturbances during the COVID-19 pandemic in a Nepalese population.Methods: This cross-sectional study recruited 206 Nepali residents who completed anonymous self-administered questionnaires. The Insomnia Severity Index (ISI) questionnaire was used to measure sleep disturbances before and after the COVID-19 pandemic. The gathered data were analyzed using descriptive statistics and inferential statistics using SPSS version 20 statistical software.Results: There was a significant variation in sleep disturbances among Nepalese residents before versus after the COVID-19 pandemic (p<0.001). The prevalence of clinical moderate insomnia has increased tremendously in Nepalese individuals. Before the pandemic’s onset, only 3.9% of the participants had moderate to severe levels of clinical insomnia; after its onset, this value increased to 17.5%. The mean ISI scores were 6.35±4.65 and 8.01±6.01 before and after the pandemic’s onset, respectively.Conclusions: Our study findings suggest that people are suffering tremendously with sleep disturbances and calls for further research and active measures to help increase sleep quality during the COVID-19 pandemic.

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        Ultrasound for thigh muscle thickness is a valuable tool in the diagnosis of sarcopenia in Indian patients with predialysis chronic kidney disease

        Namrata S. Rao,Abhilash Chandra,Sai Saran,Ayush Lohiya 대한골다공증학회 2022 Osteoporosis and Sarcopenia Vol.8 No.2

        Objectives: Patients with chronic kidney disease (CKD) are known to develop sarcopenia, an agingrelated disorder, with low muscle mass, strength and physical performance. Ultrasound-derived thigh muscle and rectus femoris thickness (TMT and RFT) can be measured easily in clinical practice, but need validation for use in predialysis CKD (stages III through V) for muscle mass estimation. The study aims to compare ultrasound-derived TMT and RFT with bioelectrical impedance analysis (BIA)-derived muscle mass estimation in the diagnosis of sarcopenia in predialysis CKD. Methods: Patients with stable CKD stage III, IV, V and not yet on dialysis were recruited, and underwent anthropometric assessment, BIA and ultrasound examination of midthigh region. Appendicular skeletal muscle index (ASMI)/height2 derived from BIA was taken as a standard for the diagnosis of low muscle mass. Gait speed and handgrip were also measured. The Asian Working Group criteria were applied. Cutoff values for low muscle mass by TMT and RFT were obtained using receiver operator curve (ROC) analysis. Results: Of the total of 117 enrolled study participants, 52 (45%) had low muscle mass, 34 (29%) had sarcopenia, of whom 79% were male, majority (38%) were CKD stage IV and had a mean age of 58 years. Using ROC analysis, TMT cutoffs of 19 mm in males and 17 mm in females were computed. Comparison of TMT cutoffs and ASMI/h2 showed good agreement between the 2 methods using Bland-Altman plots. Conclusions: Ultrasound-derived TMT and RFT can be used for muscle mass estimation in the diagnosis of sarcopenia.

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        COINCIDENCE THEOREMS VIA CONTRACTIVE MAPPINGS IN ORDERED NON-ARCHIMEDEAN FUZZY METRIC SPACES

        Gopi Prasad,Anita Tomar,Ramesh Chandra Dimri,Ayush Bartwal 한국수학교육학회 2020 純粹 및 應用數學 Vol.27 No.4

        In this article, we prove coincidence point theorems for comparable ψ-contractive mappings in ordered non-Archimedean fuzzy metric spaces utilizing the recently established concept of T -comparability and relatively weaker order theoretic variants. With a view to show the usefulness and applicability of this work, we solve the system of ordered Fredholm integral equations as an application. In the process, this presentation generalize and improve some prominent recent results obtained in Mihet [Fuzzy Sets Syst., 159 (6), 739-744, (2008)], Altun and Mihet [ Fixed Point Theory Appl. 2010, 782680, (2010)], Alam and Imdad [Fixed Point Theory, 18(2), 415-432, (2017)] and several others in the settings of partially ordered non-Archimedean fuzzy metric spaces.

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