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Amid, Reza,Kadkhodazadeh, Mahdi,Fekrazad, Reza,Hajizadeh, Farzin,Ghafoori, Arash Korean Academy of Periodontology 2013 Journal of Periodontal & Implant Science Vol.43 No.2
Purpose: The present study aimed to measure root surface roughness in teeth with periodontitis by a profilometer following root planning with ultrasonic and hand instruments with and without erbium-doped yttrium aluminium garnet (Er:YAG) laser irradiation. Methods: Sixty single-rooted maxillary and mandibular teeth, extracted because of periodontal disease, were collected. The crowns and apices of the roots were cut off using a diamond bur and water coolant. The specimens were mounted in an acrylic resin block such that a plain root surface was accessible. After primary evaluation and setting a baseline, the samples were divided into 4 groups. In group 1, the samples were root planned using a manual curette. The group 2 samples were prepared with an ultrasonic scaler. In group 3, after scaling with hand instrumentation, the roots were treated with a Smart 1240D plus Er:YAG laser and in group 4, the roots were prepared with ultrasonic scaler and subsequently treated with an Er:YAG laser. Root surface roughness was then measured by a profilometer (MahrSurf M300+RD18C system) under controlled laboratory conditions at a temperature of $25^{\circ}C$ and 41% humidity. The data were analyzed statistically using analysis of variance and a t-test (P<0.05). Results: Significant differences were detected in terms of surface roughness and surface distortion before and after treatment. The average reduction of the surface roughness after treatment in groups 1, 2, 3, and 4 was 1.89, 1.88, 1.40, and 1.52, respectively. These findings revealed no significant differences among the four groups. Conclusions: An Er:YAG laser as an adjunct to traditional scaling and root planning reduces root surface roughness. However, the surface ultrastructure is more irregular than when using conventional methods.
Amid, Azura,Chik, Wan Dalila Wan,Jamal, Parveen,Hashim, Yumi Zuhanis Has-Yun Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12
We previously found cytotoxic effects of tomato leaf extract (TLE) on the MCF-7 breast cancer cell line. The aim of this study was to ascertain the molecular mechanisms associated with the usage of TLE as an anticancer agent by microarray analysis using mRNA from MCF-7 breast cancer cells after treatment with TLE for 1 hr and 48 hrs. Approximately 991 genes out of the 30,000 genes in the human genome were significantly (p<0.05) changed after the treatment. Within this gene set, 88 were significantly changed between the TLE treated cells and the untreated MCF-7 cells (control cells) with a cut-off fold change >2.00. In order to focus on genes that were involved in cancer cell growth, only twenty-nine genes were selected, either down-regulated or up-regulated after treatment with TLE. Microarray assay results were confirmed by analyzing 10 of the most up and down regulated genes related to cancer cells progression using real-time PCR. Treatment with TLE induced significant up-regulation in the expression of the CRYAB, PIM1, BTG1, CYR61, HIF1-${\alpha}$ and CEBP-${\beta}$ genes after 1 hr and 48 hrs, whereas the TXNIP and THBS1 genes were up-regulated after 1 hr of treatment but down-regulated after 48 hrs. In addition both the HMG1L1 and HIST2H3D genes were down-regulated after 1 hr and 48 hrs of treatment. These results demonstrate the potent activity of TLE as an anticancer agent.
Linear dichroism and order parameters of nematics doped with azo dyes
Ranjkesh, Amid,Choi, Jun-Chan,Joo, Kyung-Il,Park, Hee-Won,Zakerhamidi, Mohammad Sadegh,Kim, Hak-Rin Informa UK (TaylorFrancis) 2017 Molecular Crystals and Liquid Crystals Vol.647 No.1
<P>We investigated solvent-solute effects using dye-doped nematic liquid crystals (NLCs) where three Sudan dyes of different concentrations were used as solutes doped into high- and low-polar NLCs as anisotropic solvents. The polarized spectroscopic absorption, dichroic ratio (R), and order parameter (S) were measured, which showed that the rod-like Sudan black B had a higher S and R due to a higher anisotropic solvent-solute effect produced by transition moment and global charge transfer along the molecular axis induced by high polar NLC. The order parameters measured by the Vuks method also showed a higher solvent-solute effect for the high-polar NLC.</P>
Ranjkesh, Amid,Choi, Jun-Chan,Park, Ji-Sub,Park, Min-Kyu,Kiani, Somaye,Zakerhamidi, Mohammad Sadegh,Kim, Hak-Rin Elsevier 2017 Journal of molecular liquids Vol.230 No.-
<P>The temperature dependencies of three low birefringence (Delta n) liquid crystals (LCs) at similar clearing temperatures (T-NI) were investigated to characterize the order parameter S(T) and crossover temperature (T-co). Three different methods were used to determine the S(T) property, including the Vuks model, the Haller approximation model, and a model based on the effective geometry parameter (alpha(eg)). In our low Delta n LCs with relatively analogous T-NI, three parameters (B, (Delta n)(o), and beta) that originated from the modified four-parameter model were analyzed to increase the T-co condition. A larger absolute value for the B parameter and a smaller beta parameter were also needed to reduce the temperature dependence of Delta n. In particular, a lower (Delta n)(o) value was found to be beneficial for increasing the Too value, which resulted in a higher T-co value for the low Delta n LCs, compared with that of a high An LC with a similar T-NI value. This led to a narrower temperature range between T-co and T-NI for the low Delta n LCs compared to that of the high Delta n LC, which could result in appropriate temperature properties for LCs for practical display applications, including a lower temperature dependence of Delta n and wider operational temperature regime. (C) 2017 Published by Elsevier B.V.</P>
Ranjkesh, Amid,Kiani, Somaye,Strzeż,ysz, Olga,Zakerhamidi, Mohammad Sadegh,Yoon, Tae-Hoon Elsevier 2018 Journal of molecular liquids Vol.268 No.-
<P><B>Abstract</B></P> <P>The temperature dependence of optical birefringence, order parameter, effective geometry parameter, and normalized polarizability was determined for nematic liquid crystal mixtures by measuring the refractive indices. The effects of the adjustable parameters obtained from temperature-dependent refractive indices were analyzed appropriately for the crossover temperature and order parameter values. Besides, a four-parameter power law expression method was used for the optical birefringence measurement to address inappropriate fits in the weak first-order phase transition region. From this method, the effective second order phase transition temperature <I>T</I> <SUP>⁎⁎</SUP> was determined by showing the slightly higher values than phase transition temperature. The value of the order parameter critical exponent <I>λ</I> obtained from this method showed a good agreement with the mean field theory by demonstrating closeness to the tricritical hypothesis (<I>β</I> = 0.25). As a consequence, the measurement of the temperature-dependent optical birefringence was successfully verified the pre-transitional phenomena accurately, and it can facilitate an insightful description of that region.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Temperature dependence of high birefringence (∆<I>n</I>) liquid crystals was analyzed. </LI> <LI> The temperature dependent order parameter was sorted based on ∆<I>n</I> values. </LI> <LI> Lower (∆<I>n</I>)<SUB>o</SUB> and <I>β</I> values were valuable factors for increasing <I>T</I> <SUB>co</SUB> at the same <I>T</I> <SUB>NI</SUB>. </LI> <LI> A four-parameter power law expression shows the high critical exponent value. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Ranjkesh, Amid,Yoon, Tae-Hoon American Chemical Society 2019 ACS APPLIED MATERIALS & INTERFACES Vol.11 No.29
<P>Recently, single-substrate flexible liquid crystal (LC) devices have attracted considerable attention because they can provide desirable shapes, small weight, flexibility, and rollability. In this work, we fabricate a flexible single-substrate thermoresponsive cholesteric LC (CLC) film by a facile method called photoenforced stratification method. Our fabricated single-substrate CLC film consists of microscale polymer containers filled with a CLC solution. Our results showed that the temperature response of the fabricated single-substrate CLC film depends on the chiral material doped into the CLC solution. The single-substrate ultrathin CLC film exhibits very high flexibility and robustness without performance reduction. The fabricated flexible single-substrate CLC film may pave the way for the development of novel technologies for thermoresponsive devices with changeable shapes and designs.</P> [FIG OMISSION]</BR>
Reza Amid,Mahdi Kadkhodazadeh,Reza Fekrazad,Farzin Hajizadeh,Arash Ghafoori 대한치주과학회 2013 Journal of Periodontal & Implant Science Vol.43 No.2
Purpose: The present study aimed to measure root surface roughness in teeth with periodontitis by a profilometer following root planning with ultrasonic and hand instruments with and without erbium-doped yttrium aluminium garnet (Er:YAG) laser irradiation. Methods: Sixty single-rooted maxillary and mandibular teeth, extracted because of periodontal disease, were collected. The crowns and apices of the roots were cut off using a diamond bur and water coolant. The specimens were mounted in an acrylic resin block such that a plain root surface was accessible. After primary evaluation and setting a baseline, the samples were divided into 4 groups. In group 1, the samples were root planned using a manual curette. The group 2 samples were prepared with an ultrasonic scaler. In group 3, after scaling with hand instrumentation, the roots were treated with a Smart 1240D plus Er:YAG laser and in group 4, the roots were prepared with ultrasonic scaler and subsequently treated with an Er:YAG laser. Root surface roughness was then measured by a profilometer (MahrSurf M300+RD18C system) under controlled laboratory conditions at a temperature of 25°C and 41% humidity. The data were analyzed statistically using analysis of variance and a t-test (P<0.05). Results: Significant differences were detected in terms of surface roughness and surface distortion before and after treatment. The average reduction of the surface roughness after treatment in groups 1, 2, 3, and 4 was 1.89, 1.88, 1.40, and 1.52, respectively. These findings revealed no significant differences among the four groups. Conclusions: An Er:YAG laser as an adjunct to traditional scaling and root planning reduces root surface roughness. However,the surface ultrastructure is more irregular than when using conventional methods.