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Mehdi Ahmadi,Farshid Ghanbari,Alberto Alvarez,Susana Silva Martinez 한국화학공학회 2017 Korean Journal of Chemical Engineering Vol.34 No.8
The performance of UVA-LEDs assisted peroxymonosulfate (PMS)/Fe2+ system was evaluated on carmoisine (E122) decolorization. Complete color removal was obtained under the conditions of pH=3.0, PMS=1.5mM, Fe2+=1mM and 25 min reaction time. UVA-LEDs were preferable compared to conventional UVA lamp in terms of decolorization. The functions of Co2+, Cu2+, Mn2+ and Fe2+ were compared and their results showed that Co2+ and Fe2+ had the highest efficiencies. Moreover, the presence of chloride ion showed a double role in different concentrations in which promotional effect was observed in 100mM Cl−<, while inhibitory effect occurred in 1-10mM Cl−. However, the high concentration of chloride had no influence on mineralization of E122. The scavenging results demonstrated that the UV irradiation increased the contribution of HO•. In addition, in the presence of chloride ion, HOCl along with sulfate and hydroxyl radicals were the major oxidative agents.
Daisy Pérez-Brito,Anuar Magaña-Alvarez,Patricia Lappe-Oliveras,Alberto Cortes-Velazquez,Claudia Torres-Calzada,Teófilo Herrera- Suarez,Alfonso Larqué-Saavedra,Raul Tapia-Tussell 한국미생물학회 2015 The journal of microbiology Vol.53 No.1
This study characterized Clavispora lusitaniae strains isolatedfrom different stages of the processing and early fermentationof a henequen (Agave fourcroydes) spirit produced inYucatan, Mexico using a molecular technique. Sixteen strainsidentified based on morphological features, obtained fromdifferent substrates, were typed molecularly. Nine differentversions of the divergent D1/D2 domain of the large-subunitribosomal DNA sequence were identified among theC. lusitaniae strains. The greatest degree of polymorphismwas found in the 90-bp structural motif of the D2 domain. The MSP-PCR technique was able to differentiate 100% ofthe isolates. This study provides significant insight into thegenetic diversity of the mycobiota present during the henequenfermentation process, especially that of C. lusitaniae,for which only a few studies in plants have been published. The applied MSP-PCR markers were very efficient in revealingpolymorphisms between isolates of this species.
( Alvaro March-rodriguez ),( Beatriz Bellosillo ),( Alberto Alvarez-larran ),( Carles Besses ),( Ramon M Pujol ),( Agusti Toll ) 대한피부과학회 2019 Annals of Dermatology Vol.31 No.2
Ruxolitinib is a Janus kinase (JAK)1 and JAK2 inhibitor approved for the treatment of myelofibrosis and for polycythemia patients who are resistant or intolerant to hydroxyurea. We report a 72 year-old man patient with polycythemia vera who developed multiple cutaneous squamous cell carcinomas (cSCCs) with keratoacanthoma-like histological features while on treatment with ruxolitinib. Similar lesions have been reported in an isolated patient who also received ruxolitinib. Our case confirms that ruxolitinib may induce eruptive cSCCs with characteristic clinical and histological features that differentiate them from conventional non-drug induced lesions. Moreover, we performed a mutational panel analysis of the tumors. The lack of specific mutations in these tumors suggests an impairment of immunosurveillance in the origin of the cutaneous lesions. Frequent and thorough dermatological examinations in patients receiving ruxolitinib with a history of photodamage, skin cancer and/or previous hydroxyurea intake is thus recommended. (Ann Dermatol 31(2) 204∼208, 2019)
A case of COVID-19 immediately after liver transplantation: Not only bad news
Mikel Prieto,Mikel Gastaca,Patricia Ruiz,Alberto Ventoso,Ibone Palomares,Regino Jose Rodriguez-Alvarez,Patricia Salvador,Javier Bustamante,Andres Valdivieso 한국간담췌외과학회 2020 Annals of hepato-biliary-pancreatic surgery Vol.24 No.3
COVID-19, the illness caused by the SARS-CoV-2 virus originated in December 2019 in Wuhan, China and has caused more 3,3 million cases and more than 230,000 deaths throughout the world, with 25,000 of them only in Spain, where the first case was diagnosed on January 31st, 2020. As COVID-19 is a “new” disease, we still do not have data on prognosis or treatment in transplant patients or on how to manage immunosuppression in this complex scenario. We present a case of COVID-19 diagnosed during the early postoperative period in a recipient whose liver transplantation was performed on late March during the lockdown in Spain, with donor and recipient previously negative rRT-PCR to SARS-CoV-2. In the first post-operative week the patient suffered COVID-19 pneumonia that was treated with immunosuppression minimization, oral Hydroxycloroquine and Azithromycin with favorable outcome. The patient was discharged on POD 21 without complications. To date, few early post-liver transplantation SARS-CoV-2 infected recipients have been published, but only one was an early postoperative infection. In our case the outcome was favorable, even though it was an early post -liver transplantation COVID-19 in a frail patient.
Heriberto Granados‑Becerra,Víctor H. López‑Morelos,Alberto Ruiz,Rafael García‑Hernández,Francisco F. Curiel‑López,Martin R. Barajas‑Alvarez 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.6
The Ramberg–Osgood equation was applied to model the stress–strain behavior of heat-treated and welded specimens ofInconel 600 up to 0.2 and 0.175 mm/mm of strain, respectively. As-received and aged plates of Inconel 600 were gas metalarc welded to simulate repair of a component in operation. Dog bone shape specimens were tensile tested at a cross headspeed of 0.005 s−1 and the deformation was measured with an extensometer with a gage length of 20 mm. Microstructuralobservations were made in the optical and scanning electron microscope. Fitting the experimental data in the plastic regionof stress–strain curves to a novel three slopes Ramberg–Osgood model enabled estimation of the hardening coefficient, n. The value of n varied from 0.07 to 0.3 depending on the metallurgical condition of the specimen. A notorious increase wasobserved in the value of n for samples heat-treated beyond 25 h and in as-welded samples. The results of this work showeda very good correlation between the model and the experimental curves.
Medina-Jaime, Alma Delia,Reyes-Vargas, Francianella,Martinez-Gaytan, Victoria,Zambrano-Galvan, Graciela,Portillo-DelCampo, Eduardo,Burciaga-Nava, Jorge Alberto,Reyes-Romero, Miguel,Sifuentes-Alvarez, Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7
The aim of this work was to analyze methylation of the promoter sites of the ESR1 and PGR genes and to determine correlations with immunohistochemical expression of estrogen and progesterone receptors in ductal and lobular breast cancers. An observational, descriptive, molecular study was conducted on 20 ductal and 20 lobular breast cancer samples with immunohistochemical determination of estrogen and progesterone receptor expression. The methylation analysis of ESR1 and PGR promoter sites was carried-out by methylation-specific PCR. For correlation analysis, Kendall's tau coefficient was determined. Positive correlations were found between estrogen and progesterone receptors, estrogen receptor and unmethylated progesterone receptor, progesterone receptor, and unmethylated progesterone receptor. Negative correlations were found between estrogen receptor and methylated progesterone receptor, progesterone receptor and methylated progesterone receptor, methylated and unmethylated estrogen receptor, and methylated and unmethylated progesterone receptor. The results suggest that methylation of promoter sites of ESR1 and PGR is a relatively uncommon event in ductal and lobular breast cancer, and also suggest that the determination of epigenetic states of ESR1 and PGR could represent an alternative or complement to the histopathological expression analysis.
Aleman-Gama, Elizabeth,Cornejo-Martell, Alan J.,Kamaraj, Sathish Kumar,Juarez, Katy,Silva-Martinez, Susana,Alvarez-Gallegos, Alberto The Korean Electrochemical Society 2022 Journal of electrochemical science and technology Vol.13 No.2
The high internal resistance (R<sub>int</sub>) that develops across the sediment microbial fuel cells (SMFC) limits their power production (~4/10 mW m<sup>-2</sup>) that can be recovered from an initial oil-contaminated sediment (OCS). In the anolyte, R<sub>int</sub> is related to poor biodegradation activity, quality and quantity of contaminant content in the sediment and anode material. While on the catholyte, R<sub>int</sub> depends on the properties of the catholyte, the oxygen reduction reaction (ORR), and the cathode material. In this work, the main factors limiting the power output of the SMFC have been minimized. The power output of the SMFC was increased (47 times from its initial value, ~4 mW m<sup>-2</sup>) minimizing the SMFC R<sub>int</sub> (28 times from its initial value, 5000 ohms), following the main modifications. Anolyte: the initial OCS was amended with several amounts of gasoline and kerosene. The best anaerobic microbial activity of indigenous populations was better adapted (without more culture media) to 3 g of kerosene. Catholyte: ORR was catalyzed in birnessite/carbon fabric (CF)-cathode at pH 2, 0.8M Na<sub>2</sub>SO<sub>4</sub>. At the class level, the main microbial groups (Gammaproteobacteria, Coriobacteriia, Actinobacteria, Alphaproteobacteria) with electroactive members were found at C-anode and were associated with the high-power densities obtained. Gasoline is more difficult to biodegrade than kerosene. However, in both cases, SMFC biodegradation activity and power output are increased when ORR is performed on birnessite/CF in 0.8 M Na<sub>2</sub>SO<sub>4</sub> at pH 2. The work discussed here can focus on bioremediation (in heavy OCS) or energy production in future work.
Rodolfo Valdés,Andrés Tamayo,Marcos González,Sigifredo Padilla,Déborah Geada,William Ferro,Lorely Milá,Leonardo Gómez,Rosario Alemán,Alberto Leyva,Cristina García,Otto Mendoza,Tatiana Alvarez,Lamay Do 한국생물공학회 2012 Biotechnology and Bioprocess Engineering Vol.17 No.1
Monoclonal antibody (mAb) production methods (ascites, in vitro technologies, transgenic animals, and dicot or monocot transgenic plants; moss, algae) have been improved since they were first developed in 1975. In this study, we illustrate a summary of a study case in which mice, a hollow fiber system, and tobacco transgenic plants were assessed for the production of mAb for vaccine manufacturing and vaccine production. Monoclonal antibody (mAb) production methods (ascites, in vitro technologies, transgenic animals, and dicot or monocot transgenic plants; moss, algae) have been improved since they were first developed in 1975. In this study, we illustrate a summary of a study case in which mice, a hollow fiber system, and tobacco transgenic plants were assessed for the production of mAb for vaccine manufacturing and vaccine production.
Dí,ez, Blanca,Cuadrado, Purificació,n,Marcos-Ferná,ndez, Á,ngel,de la Campa, José,G.,Tena, Alberto,Prá,danos, Pedro,Palacio, Laura,Lee, Young Moo,Alvarez, Cristina Elsevier 2018 Reactive & functional polymers Vol.127 No.-
<P><B>Abstract</B></P> <P>Two series of aromatic poly(<I>ortho</I>-hydroxyamide)s (poly(<I>o</I>-hydroxyamide)s, HPAs) were prepared by reaction of two diamines, 2,2-bis(3-amino-4-hydroxyphenyl) propane (APA) and 2,2-bis(3-amino-4-hydroxyphenyl) hexafluoropropane (APAF), with four aromatic diacid chlorides; terephthaloyl dichloride (TPC), isophthaloyl dichloride (IPC), 2,2-bis[4-chlorocarbonylphenyl)hexafluoropropane (6FC) and 4,4′-sulfonyldibenzoyl dichloride (DBSC). Amorphous HPAs with high molecular weights (inherent viscosities higher than 0.5 dL/g) and relatively high glass transition temperatures (220–280 °C) were obtained. Dense membranes of HPAs were able to undergo a thermal rearrangement (TR) process to polybenzoxazoles (β-TR-PBOs) heating at moderate temperatures (between 250 and 375 °C), and their complete conversion was reached at a temperature below 375 °C, depending on the <I>o</I>-hydroxy diamine moiety, APA and APAF. The β-TR-PBOs films derived from APAF showed a higher thermal stability and higher Tg than those from APA. Gas separation properties of TR-PBOs membranes were superior to those of their poly(<I>o</I>-hydroxyamide) precursors, particularly for the following gas pairs: O<SUB>2</SUB>/N<SUB>2</SUB>, CO<SUB>2</SUB>/CH<SUB>4</SUB>, He/CH<SUB>4</SUB> and He/CO<SUB>2</SUB>.</P>