Optimum design of RC shallow tunnels in earthquake zones using artificial bee colony and genetic algorithms

Hasan Tahsin Öztürk,Erdem Turkeli,Ahmet Durmus 사단법인 한국계산역학회 2016 Computers and Concrete, An International Journal Vol.17 No.4

The main purpose of this study is to perform optimum cost design of cut and cover RC shallow tunnels using Artificial bee colony and genetic algorithms. For this purpose, mathematical expressions of objective function, design variables and constraints for the design of cut and cover RC shallow tunnels were determined. By using these expressions, optimum cost design of the Trabzon Kalekapısı junction underpass tunnel was carried out by using the cited algorithms. The results obtained from the algorithms were compared with the results obtained from traditional design and remarkable saving from the cost of the tunnel was achieved.

Endocan and Non-Dipping Circadian Pattern in Newly Diagnosed Essential Hypertension

Tolga Çimen,Murat Bilgin,Ahmet Akyel,Mehmet Ali Felekoğlu,Ali Nallbani,Şeyda Özdemir,Gönül Erden,Alpaslan Öztürk,Mehmet Doğan,Ekrem Yeter 대한심장학회 2016 Korean Circulation Journal Vol.46 No.6

Background and Objectives: Non-dipper hypertension is frequently accompanied by endothelial dysfunction and activation. Previous studies suggested that endocan may be a novel endothelial dysfunction marker. This study aims to investigate the association between circadian blood pressure (BP) pattern and plasma endocan levels together with high-sensitivity C-reactive protein (hsCRP) in patients with newly diagnosed untreated hypertension. Subjects and Methods: Twenty-four hour ambulatory blood pressure monitoring was recorded in 35 dipper, 35 non-dipper hypertensives and 35 healthy controls. Endocan levels were measured by enzyme-linked immunosorbent assay. Serum levels of hsCRP were also recorded. Results: Despite similar daytime and 24-hour average BP values between dippers and non-dippers, statistically significant high nocturnal BP was accompanied by a non-dipping pattern (Systolic BP: 132±9 vs. 147±11 mmHg; Distolic BP: 80±7 vs. 91±9 mmHg, respectively, p<0.001 for both). Non-dipper patients demonstrated higher endocan levels compared to dippers and normotensives (367 (193-844) pg/mL, 254 (182-512) pg/mL and 237 (141-314) pg/ml, respectively, p<0.001). HsCRP levels were significantly higher in non-dippers than the other groups (p=0.013). In a multivariate logistic regression analysis, endocan (p=0.021) and hsCRP (p=0.044) were independently associated with a non-dipping pattern. Conclusion: Elevated endocan levels were found in non-dipper groups. Endocan and hsCRP were found to be independently associated with a non-dipping pattern. We suggest that elevated levels of endocan in non-dipper hypertensive patients might be associated with a longer duration of exposure to high BP. These results point to the possible future role of endocan in selection of hypertensive patients at higher risk or target organ damage

A reliable approach for determining concrete strength in structures by using cores

Ayşegül Durmuş,Hasan Tahsin Öztürk,Ahmet Durmuş 사단법인 한국계산역학회 2013 Computers and Concrete, An International Journal Vol.11 No.5

As known, concrete classes are described as strength of standard specimens produced and kept in ideal conditions, not including reinforcement and not subjected to any load effect before. Under the circumstances, transforming core strengths to the standard specimen strength is necessary and considering all parameters, affected on the core strength, is inevitable. In fact, effects of the reinforcement and the load history on concrete strength are generally neglected when these mentioned transforms are performing. The main purpose of this paper is investigating the effects of the reinforcement and the load history on the core strength. This investigation is experimentally performed on cores drilled from specimens having different keeping conditions, reinforced, unreinforced, subjected to bending and central pressure in various proportions of failure load during specified periods. Obtained results show that the importance of these effects cannot be neglected.

Functional Outcomes and Long-term Durability of Artificial Urinary Sphincter Application: Review of 56 Patients With Long-term Follow-up

Ömer Gülpınar,Evren Süer,Mehmet İlker Gökce,Ahmet Hakan Haliloğlu,Erdem Öztürk,Nihat Arıkan 대한비뇨의학회 2013 Investigative and Clinical Urology Vol.54 No.6

Purpose: To evaluate the long-term outcomes of artificial urinary sphincter (AUS) implantation and to report the complication rates, including mechanical failure, erosion,and infection. Materials and Methods: From June 1990 to May 2011, AUS (AMS 800) implantations were performed in 56 adult males by one surgeon. Various demographic and preoperative variables, surgical variables, and postoperative outcomes, including success and complication rates with a median follow-up of 96 months, were recorded retrospectively. Results: The mean age of the patients at the time of AUS implantation was 61.8 (±14.2)years. During the follow-up period, the total complication rate was 41.1% (23 patients). The incidence of complications was significantly lower during the follow-up period after 48 months (p<0.05). Kaplan-Meier analysis revealed that 5- and 10-year failure-free rates were 50.3% and 45.2%, respectively. Conclusions: Long-term durability and functional outcomes are achievable for the AMS 800, but there are appreciable complication rates for erosion, mechanical failure, and infection of up to 30%.

Effects of housing conditions on stress, depressive like behavior and sensory-motor performances of C57BL/6 mice

İsmail Abidin,Hatice Keser,Elif Şahin,Hilal Öztürk,Harun Başoğlu,Ahmet Alver,Selcen Aydin-Abidin 한국실험동물학회 2024 Laboratory Animal Research Vol.40 No.1

Background: The effects of housing conditions on animal physiology, behavior or stress are still debated. The aim of this study was to investigate the effects of three different housing systems, individually ventilated cages (IVC), classical small cages with floor surface area of 500 cm2 (CC500) and classical large cages with floor surface area of 800 cm2 (CC800) on body weight, sensory-motor performances, depression-like behavior, plasma corticosterone and brain oxidative stress parameters in C57BL/6 mice. The mice housed in one of the cages from birth to 6 months of age. Hang wire and adhesive removal tests were performed to evaluate somatosensory and motor performances. The extent of depression was determined by the forced swim test. Blood corticosterone levels were measured. In addition, brain malondialdehyde (MDA), total antioxidant status (TAS) and total oxidant status (TOS) levels were analyzed. Results: The depression-like behavior of the groups was similar. Although there were no significant differences in hang wire test among groups, CC500 group required longer durations in adhesive removal test. The body weight and plasma corticosterone levels of CC800 group were significantly higher than other groups. The oxidative stress parameters were highest in CC500 cage. Conclusions: Our study showed that the least stressful housing condition was IVC cage systems. Interestingly, the number of mice in the classical cages had a significant effect on stress levels and sensory-motor performance. Background: The effects of housing conditions on animal physiology, behavior or stress are still debated. The aim of this study was to investigate the effects of three different housing systems, individually ventilated cages (IVC), classical small cages with floor surface area of 500 cm2 (CC500) and classical large cages with floor surface area of 800 cm2 (CC800) on body weight, sensory-motor performances, depression-like behavior, plasma corticosterone and brain oxidative stress parameters in C57BL/6 mice. The mice housed in one of the cages from birth to 6 months of age. Hang wire and adhesive removal tests were performed to evaluate somatosensory and motor performances. The extent of depression was determined by the forced swim test. Blood corticosterone levels were measured. In addition, brain malondialdehyde (MDA), total antioxidant status (TAS) and total oxidant status (TOS) levels were analyzed. Results: The depression-like behavior of the groups was similar. Although there were no significant differences in hang wire test among groups, CC500 group required longer durations in adhesive removal test. The body weight and plasma corticosterone levels of CC800 group were significantly higher than other groups. The oxidative stress parameters were highest in CC500 cage. Conclusions: Our study showed that the least stressful housing condition was IVC cage systems. Interestingly, the number of mice in the classical cages had a significant effect on stress levels and sensory-motor performance.

Effects of Cognitive Behavioral Therapy, Existential Psychotherapy and Supportive Counselling on Facial Emotion Recognition Among Patients with Mild or Moderate Depression

Onur Yılmaz,Ali Barlas Mırçık,Merve Kunduz,Müge Çombaş,Ahmet Öztürk,Erdem Deveci,İsmet Kırpınar 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.7

Objective This study compared the effects of cognitive behavioral therapy (CBT), existential psychotherapy (ExP) and supportive counseling (SUP) on facial emotion recognition among mildly and moderately depressed patients. Methods 21 patients for CBT, and 20 each for ExP and SUP groups with 60 healthy controls were investigated. Eight consecutive weekly sessions and following two monthly boosters were performed. Prior to the sessions, all subjects received Sociodemographic Data Form, the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-1), and Facial Emotion Recognition Test (FERT). Patients received Hamilton Depression Rating Scale (HDRS) and FERT at the onset and after weekly and booster sessions. Results Patients’ ability to recognize surprised and neutral emotions were lower than controls. ExP group improved recognition of almost all emotions, CBT group improved only happy emotions and SUP group did not improve any emotions. HDRS scores declined in all patient groups, ExP and CBT groups had lower scores than SUP. Conclusion MDD patients recognized surprised and neutral emotions lower than controls. ExP improved ability to recognize almost all emotions, CBT improved only happy emotions, SUP did not improve at all. ExP, CBT and SUP all led to a reduction in MDD. ExP and CBT had comparable effects and both were more helpful than SUP.