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SPECTRUM CONVOLUTION OF FULL TRANSFORMATION SEMIGROUP
Adeniji, Adenike Olusola The Honam Mathematical Society 2019 호남수학학술지 Vol.41 No.3
In this paper, some results are obtained from studying convolution on the spectrum of full transformation semigroup and some of its subsemigroups using Cayley's table. The shift of ${\alpha}$ determines its eigenvalues and one-dimensional linear convolution is complex in Symmetric group.
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Spectrum convolution of full transformation semigroup
A. O. Adeniji 호남수학회 2019 호남수학학술지 Vol.41 No.3
In this paper, some results are obtained from studying convolution on the spectrum of full transformation semigroup and some of its subsemigroups using Cayley's table. The shift of $\alpha$ determines its eigenvalues and one-dimensional linear convolution is complex in Symmetric group.
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Shola Elijah Adeniji,Abduljelil Ajala,David Ebuka Arthur,Mustapha Abdullahi,Omole Isaac Areguamen 한국고분자학회 2022 Macromolecular Research Vol.30 No.9
Chemometric validation of the reported experimental activities of nicotinamide and carboxamide analogues against diabetes were determined via quantitative structure-activity relationship (QSAR) model using ATS1p, AATSC1m, nHother and RDF80p descriptors. Meanwhile, GPBAR_HUMAN with a UniProtKB code (Q8TDU6) for G protein-coupled bile acid was known as a potential drug target in human TGR5 of Type 2 diabetes mellitus (T2DM) whose crystal structure wasn’t found in the Protein Data Bank. With the aid of in-Silico approach via homology modeling helps to build a 3D protein (target) model with the availability of GPBAR_HUMAN sequence data. The swiss-Model online workspace was used to model the GPBAR_HUMAN receptor using the Cryo-EM structure of the INT-777-bound GPBAR-Gs complex with PDB code (7CFN) as a potential template. The built receptor was evaluated, validated, and used as a target protein for molecular docking simulation of some potent nicotinamide and carboxamide series. The virtual screening studies via molecular docking revealed the binding pockets, binding modes and poses of the GPBAR_HUMAN receptor with some prominent anti-diabetic agents. Analysis of these interactions led to computational design via a structure-based approach of new potent anti-diabetic compounds with significant binding scores and better interactions with the GPBAR_HUMAN receptor. Validation of the designed compounds via Drug-likeness and ADME prediction confirmed that these compounds are orally bioavailable with a good lipophilicity index for lipid environments and show zero violation to the drug assessment rules in order to be considered as drug candidates. Therefore, in-vitro and an in-vivo test to transform these findings into potent therapeutics are strongly recommended.
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A.A. Adeniji,M.C. Kekana,M.Y. Shatalov 한국전산응용수학회 2023 Journal of applied mathematics & informatics Vol.41 No.5
This paper summarizes some research findings that show how the differential transform method (DTM) is used to resolve the Holling-Tanner model. To confirm the application, effectiveness, and correctness of the approach, a comparison between the differential transform method (DTM) and the Adomian decomposition method (ADM) is carried out, and an accurate solution representation in truncated series is discovered. The approximate solution obtain using both techniques and comparison demonstrates same outcome which remains a preferred numerical method for resolving a system of nonlinear differential equations.
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Adebayo David Oluwole,Emily Oluyemisi Adeniji,Olayemi Jumoke Abiodun-Oyebanji 강원대학교 인문과학연구소 2022 Journal of Humanities Therapy Vol.13 No.2
This study was designed to investigate presumptive behaviours (spirituality, health-seeking behaviour and illness cognition) on the psychological well-being of academic staff in tertiary institutions in Ogun State, Nigeria. A descriptive survey design was used. A simple random technique was employed from three purposively selected tertiary institutions in Ogun State to select 208 respondents representing 10.1% of 2,050 academic staff. Namely Federal College of Education Abeokuta (83 - 39.9%), Moshood Abiola Polytechnic (75 - 36.1%) and Federal University Agricultural (FUNNAB) (50 - 24.0%). The instruments used were the health-seeking behaviour questionnaire, psychological well-being scale, spirituality self-report questionnaire and brief illness perception questionnaire. The data to be obtained was analysed using descriptive statistics and Multiple regression. Results showed that except for spirituality, there was a significant relationship between the independent variables (health-seeking behaviour, and illness cognition factors) and psychological well-being among lecturers in some selected institutions in Ogun State, Nigeria. There was a significant composite contribution of health-seeking behaviour, spirituality and illness cognition and psychological well-being among lecturers in some selected institutions in Ogun State, Nigeria. Implications and recommendations were discussed.
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Olubunmi Atolani,Gabriel A. Olatunji,Oluwatoyin Adenike Fabiyi,Adekunle J. Adeniji,Omonike O. Ogbole 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.10
Studies suggest that the traditional applications of Kigelia pinnata leaves have beneficial effects against oxidative stress–mediated diseases and cancers. The pulverized dried leaves of K. pinnata were extracted with hexane, ethylacetate, and methanol sequentially, and the crude extracts were fractionated by silica gel column chromatography with solvent gradient of increasing polarity. 3-hydro-4,8-phytene, trans-phytol, (9Z,12Z)-methyl octadeca-9,12-dienoate, and two oil fractions were obtained. The chemical compositions of chromatographic fractions were determined using gas chromatography–mass spectroscopy. The structure elucidations of the isolated compounds were based on FTIR, MS, and NMR spectral data analyses. These along with the crude extracts were examined for their antioxidant activities using ferric reducing antioxidant power (FRAP), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, and 2,2-azinobis(3-ethyl-benzothiazoline-6-sulfonic acid)(ABTS) assays. Total phenolic contents were also determined. The crude extracts and purified compounds were evaluated on the rhabdomyosarcoma human cancer cell for their cytotoxicity using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) cell viability assays. The methanol extract was richer in phenolics and was most potent as antioxidant and cytotoxic agent among all the substances tested. Among the fractions and pure compounds, the two oil fractions showed more cytotoxicity potency, with IC50s of 143.4 – 0.5 and 147.9 – 1.3 ng/mL, which is more significant than the reference standard, cyclophosphamide (165.6 – 1.0 ng/mL). 3-hydro-4,8-phytene showed lower antioxidant and cytotoxicity potential (IC50 = 1818 – 5.2 lg/mL and 171.7 – 0.8 ng/mL, respectively). Trans-phytol did not show a high cytotoxic power (IC50 =769.8 – 4.3 ng/mL). The comparatively high cytotoxicity index of (9Z, 12Z)-methyl octadeca-9,12-dienoate (IC50 = 153.3 –0.1 ng/mL) indicated that it may be one of the principal cytotoxic agent in the ethyl acetate extract. These results suggest that the leaves of K. pinnata possess tumor cytotoxic potential and could be part of a drug combination for future cancer chemotherapy.
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