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중학생의 완벽주의와 학업적 그릿의 관계: 실패마인드셋의 매개효과
최성아,하정희 한국청소년복지학회 2022 청소년복지연구 Vol.24 No.4
본 연구는 청소년의 완벽주의 성향이 학업적 그릿에 미치는 영향을 알아보고, 완벽주의와 학업적 그릿의 관계에서 실패마인드셋의 매개효과를 검증하고자 하였다. 이를 위해 현재 중학교에 재학 중인 중학생 299명을 대상으로 다차원적 완벽주의 척도(HMPS), 학업적 그릿 척도, 실패마인드셋 척도를 사용하여 설문을 시행하였다. 수집된 자료는 SPSS 24.0과 AMOS 24.0을 활용하여 분석하였으며, 연구결과는 다음과 같다. 첫째, 자기지향 완벽주의는 사회부과 완벽주의, 성장적 실패마인드셋, 학업적 그릿과 모두 정적으로 유의미한 상관이 있었으며 퇴보적 실패마인드셋과는 상관관계가 유의미하지 않은 것으로 나타났다. 사회부과 완벽주의는 성장적 실패마인드셋, 학업적 그릿과 모두 부적으로 유의미한 상관관계가 있었으며, 퇴보적 실패마인드셋과는 정적으로 유의미한 상관관계를 나타냈다. 둘째, 자기지향 완벽주의는 학업적 그릿에 직접적으로 영향을 미치고 실패마인드셋을 통해서 간접적으로 영향을 미치지 않는 것을 확인하였다. 셋째, 사회부과 완벽주의는 학업적 그릿에 직접적인 영향을 미치지 않고 성장적 실패마인드셋을 통해서 간접적으로 영향을 미치는 것을 확인하였다. 본 연구는 청소년의 완벽주의와 학업적 그릿의 관계를 설명한 연구의 범위를 확장하였으며 완벽주의 성향으로 인해 학업적 어려움을 겪는 청소년들과 그들을 교육하는 교육자가 적용할 수 있는 교육적 처치의 개입 방향을 제시했다는 점에서 의의가 있다.
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적외선 열화상장치를 이용한 Buchanan plugger 표면의 온도상승 분석
최성아,황인남,오원만 전남대학교 치의학연구소 2002 구강과학 Vol.14 No.1
This study was performed to evaluate the temperature rise on various position of the Buchanan plugger, the peak temperature of plugger's type and the temperature change by its touching time of heat control spring. The heat carrier system 'System B' (Model 1005, Analytic Technologies, USA) and the Buchanan's pluggers of F, FM, M and ML sizes are used for this study. The temperature was set to 200℃ which Dr. Buchanan's "continuous wave of condensation" technique recommended on digital display and the power level on it was set to 10. In order to apply heat on the Buchanan's pluggers, the heat control spring was touched for 1, 2, 3, 4 and 5seconds respectively. The temperature rise on the surface of the pluggers were measured at 0.5 mm intervals from tip to 20mm length of shank using the infrared thermography (Radiation Thermometer-IR Temper, NEC San-ei Instruments, Ltd. Japan) and TH31-702 Data capture software program (NEC San-ei Instruments, Ltd, Japan). Data were analyzed using a one way ANOVA followed by Duncan's multiple range test and linear regression test. The results as follows. 1. The position at which temperature peaked was approximately at 0.5mm to 1.5mm far from the tip of Buchanan's pluggers (p<0.001). The temperature was constantly decreased toward the shank from the tip of it(p<0.001). 2. When the pluggers were heated over 5seconds, the peak temperature by time of measurement revealed from 253.3±10.5℃ to 192.1±3.3℃ in a touch for 1sec, from 218.6±5.0℃ to 179.5±4.2℃ in a touch for 2sec, from 197.5±3.0℃ to 167.6±3.7℃ in a touch for 3sec, from 183.7±2.5℃ to 159.8±3.6℃ in a touch for 4sec and from 164.9±2.0℃ to 158.4±1.8℃ in a touch for 5 sec. A touch for 1sec showed the highest peak temperature, followed by , in descending order, 2sec, 3sec, 4sec. A touch for 5sec showed the lowest peak temperature(p<0.001). 3. A each type of pluggers showed different peak temperatures. The peak temperature was the highest in F type and followed by, in descending order, M type, ML type, FM type revealed the lowest peak temperature(p<0.001). The results of this study indicated that pluggers are designed to concentrate heat at around its tip, its actual temperature does not correlate well with the temperature which Buchanan's "continuous wave of condensation" technique recommend, and finally a quick touch of heat control spring for 1sec reveals the highest temperature rise.
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Dynamic Regulation of APE1/Ref-1 as a Therapeutic Target Protein
최성아,주희경,전병화 전남대학교 의과학연구소 2016 전남의대학술지 Vol.52 No.2
Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) is a multifunctionalprotein that plays a central role in the cellular response to DNA damage and redoxregulation against oxidative stress. APE1/Ref-1 functions in the DNA base excision repairpathway, the redox regulation of several transcription factors, and the control ofintracellular redox status through the inhibition of reactive oxygen species (ROS)production. APE1/Ref-1 is predominantly localized in the nucleus; however, its subcellularlocalization is dynamically regulated and it may be found in the mitochondriaor elsewhere in the cytoplasm. Studies have identified a nuclear localization signal anda mitochondrial target sequence in APE1/Ref-1, as well as the involvement of the nuclearexport system, as determinants of APE1/Ref-1 subcellular distribution. Recently,it was shown that APE1/Ref-1 is secreted in response to hyperacetylation at specificlysine residues. Additionally, post-translational modifications such as phosphorylation,S-nitrosation, and ubiquitination appear to play a role in fine-tuning the activitiesand subcellular localization of APE1/Ref-1. In this review, we will introduce themultifunctional role of APE1/Ref-1 and its potential usefulness as a therapeutic targetin cancer and cardiovascular disease.
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