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부분 간절제술을 시행한 랫드에서 간재생에 관한 이과두주 급성투여에 따른 영향
조진연 ( Jin Youn Cho ),송지예 ( Ji Yae Song ),안재범 ( Jae Bum Ahn ),김현석 ( Hyun Seok Kim ),김민수 ( Min Su Kim ),임현 ( Hyun Im ),임준성 ( Jun Sung Lim ),신동석 ( Dong Seok Shin ),김현철 ( Hyun Chul Kim ),정기수 ( Ki Soo Jung 한국가축위생학회 2006 韓國家畜衛生學會誌 Vol.29 No.1
Alcoholism and alcohol abuse are major public health concerns. This is linked to the injury of many organs, especially liver. Experiments were performed to know the acute effects of LeeKwaDoo(LKD) induced by two-third partial hepatectomy(PH) in rats. In liver samples, regeneration parameters and histological assessment were performed. For the blood biochemical study, the blood were assayed with AST, ALT. The portal branch of liver lobes was ligated in the male Sprague-Dowley rats, two-thirds partial hepatectomies were also performed. It was estimated bodyweight and relative liver weight for the index of liver For the marker of blood chemistry, we investigate the serum sample of rats and demonstrated the level of AST, ALT. Remaining tissues of liver developed as microscopic structures. Resection of the lobes in PH+LKD group resulted in a marked change of liver weight, blood chemistry and histological changes. The initiation of the proliferative response in PH group stimulated as well as reduction of the liver mass. On the other hands, the initiation of the proliferative response in PH+LKD group delayed. Eventually, both PH group and PH+LKD group was restored relative liver weigh after 7 day. In conclusion, the acute adminstration of LKD seems to inhibit the initial response of liver regeneration through alcohol effects.
직접 수치 모사법을 이용한 섬유 강화 복합재료의 열팽창계수 예측
남윤식(Youn-Sic Nam),오민환(Min Hwan Oh),김광식(Kwang Sik Kim),조진연(Jin Yeon Cho) 한국항공우주학회 2007 韓國航空宇宙學會誌 Vol.35 No.9
본 논문에서는 직접 수치 모사 기법을 이용해 섬유 강화 복합재료의 열팽창계수를 예측하였다. 직접 수치 모사 기법을 통해 구한 열팽창계수 예측치와 실험치의 비교를 통해 본 논문에서 제안한 직접 수치 모사 기법을 이용하면 인위적인 가정을 최소화하면서 기존의 방법과 유사하게 복합재료 열팽창계수를 예측할 수 있음을 확인하였다. 또한 섬유 체적비 변화에 따른 열팽창계수의 변화를 예측하고 그 경향성을 고찰하였다. In this paper, thermal expansion coefficients of fiber-reinforced composite materials are predicted by direct numerical simulation. From comparing the predicted results with experimental results, it is confirmed that direct numerical simulation gives similar results to the previously proposed methods while minimizing artificial assumptions. Additionally trend of variation in thermal expansion coefficients is investigated according to the fiber volume fraction.