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한국에서 지역에 따른 Helicobacter pylori 균주 내성
김재연 ( Jae Yeon Kim ),김나영 ( Na Young Kim ),김성중 ( Sung Jung Kim ),백광호 ( Gwang Ho Baik ),김광하 ( Gwang Ha Kim ),김정목 ( Jung Mogg Kim ),남령희 ( Ryoung Hee Nam ),김홍빈 ( Hong Bin Kim ),이동호 ( Dong Ho Lee ),정현채 ( H 대한소화기학회 2011 대한소화기학회지 Vol.57 No.4
Background/Aims: This study was performed to compare the prevalence rates of primary antibiotic resistance in Helicobacter pylori (H. pylori) isolates among different regions of Korea. Methods: H. pylori were isolated from gastric mucosal biopsy specimens of 99 Koreans who lived in Gyeonggi (n=40), Kangwon province (n=40) and Busan (n=19) from April to August in 2008. All the patients had no history of H. pylori eradication therapy. The susceptibilities of the H. pylori isolates to amoxicillin, clarithromycin, metronidazole, tetracycline, azithromycin, ciprofloxacin, levofloxacin, and moxifloxacin were tested according to the agar dilution method. Results: There was a difference in resistance to clarithromycin in three institutes located among Gyeonggi (32.5%), Kangwon province (12.5%) and Busan (42.1%) by One way ANOVA test (p=0.027) and nonparametric Kruskal Wallis test (p=0.027). However, by post-hoc analysis, there was no statistically significant difference among three regions. Similarly, the other 7 antibiotics (amoxicillin, metronidazole, tetracycline, azithromycin, ciprofloxacin, levofloxacin and moxifloxacin) did not show any significant difference. Conclusions: There was no significant regional difference of the primary antibiotic resistance of H. pylori. However, the included patient number might not be enough for this conclusion demanding further evaluations. (Korean J Gastroenterol 2011;57:221-229)
김용태(Y . T . Kim),유권(K . Yoo),정현채(H . C . Jung),이효석(H . S . Lee),윤용범(Y . B . Yoon),송인성(I . S . Song),최규완(K . W . Choi),김정룡(C . Y . Kim),최병인(B . I . Choi),최상운(S . W . Choi) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.2
N/A To investigate the prevalance of cholelithiasis in liver cirrhosis, a retrospective study using biliary ultrasonography was performed in 222 patients with liver eirrhosis and in 177 controls. Gallstones were found more often in cirrhotic patients (13.5%) than in controls (5.6%) (p<0.05). Their prevalence was the same in both sexes. The prevalence of gallstone increased in decompensated liver cirrhosis (p<0.05). The prevalence was higher in HBs-Ag negative liver cirrhosis than HBs-Ag positive liver cirrhosis (p<0.01). The linear trend of increasing prevalence with increasing age in non cirrhotic group was not observed in patients with liver cirrhosis. This study confirms, by means of sonography, the high prevalence of cholelithiasis in liver cirrhosis in Korean adults.