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강교량의 기획단계에서의 환경부하 평가 및 영향요인에 관한 연구
전민영,경갑수,이성진,류성진,Jeon, Min Yeong,Kyung, Kab Soo,Lee, Sung Jin,Ryu, Seong Jin 한국강구조학회 2016 한국강구조학회 논문집 Vol.28 No.1
최근 들어 다양한 분야에서 환경오염에 대한 관심이 높아지고 있으며 환경부하를 산출하는 환경적합성평가방법인 전과정평가에 관한 연구는 현재 많이 진행되고 있다. 그러나 SOC 시설물은 다양한 자재, 공정과정을 거치기 때문에 환경에 많은 영향을 미칠 것으로 예상되나 아직까지는 환경오염에 대한 대책 및 연구가 부족한 것으로 판단된다. 본 연구에서는 2000년 이후 설계된 204개 강교에 대한 데이터를 구축하였으며, 그 중 100개 교량을 대상으로 기획단계에서의 전과정평가를 실시하여 환경부하량을 산출하였다. 또한 강교에 대한 표준 공종 분류체계를 정립하였고, 이를 바탕으로 교량의 기본 설계 자료와 투입자재에 LCI DB를 적용하여 소요자재별 환경부하량을 산정하고 이를 Eco-point 값으로 나타내었다. 본 연구에서 도출된 환경부하량은 향후 강교의 설계에서 전과정평가 과정에 대한 기초자료로서 활용될 수 있을 것으로 판단된다. Recently, interest for environmental pollution in various fields is on the increase, and the researches on the life cycle assessment of environmental performance assessment method for calculating the environmental loads are currently most performed. It is expected to have a significant influence on the environment, since SOC infrastructures are go through a variety of materials, manufacturing process, however it is judged that researches and measures for environmental pollution is insufficient. In this study, we build the data for 204 of steel bridge designed after 2000 year, and the 100 of bridge which were selected to from obtained results were calculated the environmental loads at the planning stage based on the life cycle assessment. In addition, standard classification systems in work type for steel bridges were established. Based on this, the basic design data and input materials for the bridges are applied to the LCI DB, and the environmental load for required material is evaluated and is shown as Eco-point. Environmental loads obtained from this study, it is judged that can be utilized as a basic data for the process of the life cycle assessment in future steel bridge design.
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RAW 264.7 cell에서의 미모사 에탄올 추출물의 항산화 및 항염증 효능 연구
전민영 ( Min Yeong Jeon ),김배환 ( Bae-hwan Kim ) 한국동물실험대체법학회 2020 동물실험대체법학회지 Vol.14 No.1
The purpose of this study is to identify the possibility of Mimosa pudica ethanol extracts (MEE) as a cosmeceutical material with antioxidant and anti-inflammatory effects. At first, the antioxidant effect of the MEE was carried out through Total polyphenol, 2,2diphenyl-1- picrylhydrazyl (DPPH) electro-donating activity, 2,2’-azino-bis diammonium salt (ABTS<sup>+</sup>) radial scavenging activity. The total polyphenol content of the MEE was 3.514 mg/g. DPPH electro-donating activity of MEE were increased in a dose-dependent manner (P<0.05), and was about 88.1% at 1 mg/mL concentration. Also, ABTS<sup>+</sup> radical scavenging activity of MEE were remarkably increased in a dose-dependent manner (P<0.05), and was about 99.7% at 1 mg/mL concentration. The MEE showed relatively high antioxidant effects in most experiments. To evaluate the anti-inflammatory effects in RAW 264.7 cells, the maximum permissible concentration was verified first by cell viability assessment using MTT assay. And then, nitric oxide (NO) production inhibition and amounts of inflammatory related proteins and gene expressions were identified after LPS treatment. NO inhibition of MEE was decreased concentration dependently, and was about 84.3% at 1 mg/mL concentration. And TNF-α and IL-6 proteins by western blotting were also decreased significantly by treatment of MEE. As a result of measuring the expression levels of TNF-α and IL-6, the expression inhibition rates were 67.87% and 71.91%, respectively. Based on the results of these experiments, we suggest that MEE could be useful as a cosmeceutical material with anti-inflammatory effects.
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