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정혜정 ( Hye Jung Jung ),박미연 ( Mi Youn Park ),윤재일 ( Jai Il Youn ),안지영 ( Ji Young Ahn ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.6
Department of Dermatology, National Medical Center, Seoul, Korea Background: Allergic skin diseases such as atopic dermatitis and urticaria are known to be mediated by IgE. It is important to confirm a causative allergen for diagnosis and treatment. The multiple allergosorbent test (MAST) is a simple method for simultaneously measuring total and allergen-specific IgE. Objective: The purpose of this study was to analyze results from the MAST, which measures total and specific IgE, and to compare the different results. Methods: We reviewed the MAST results of 270 allergic disease patients tested between June 2007 and May 2012. Results: There were statistical differences in total IgE production and in positive sensitization to specific allergens between the disease groups. The level of total IgE and positive rates of specific IgE were highest in atopic dermatitis patients, followed by urticaria, allergic contact dermatitis, and pruritus patients. Atopic dermatitis patients had significantly more allergens than those with other diseases. There were no statistical differences in total IgE level, rates of positive sensitization to specific allergens, and the number of causative allergens between the patients with acute and chronic urticaria. Conclusion: Each disease showed a different IgE pattern. Atopic dermatitis showed the highest level of serum IgE. There were no differences in IgE levels between acute and chronic urticaria patients. We identified an increase in IgE level in allergic contact dermatitis patients. Further study is needed to determine whether these patterns could be useful in diagnosis and choice of treatment methods. (Korean J Dermatol 2014;52(6):387∼393)
피부 악성 종양의 통계적 고찰 ( 1990년 - 1995년 )
문상은 ( Sang Eun Moon ),조광현 ( Kwang Hyun Cho ),황지환 ( Ji Hwan Hwang ),김정애 ( Jeong Aee Kim ),윤재일 ( Jai Il Youn ) 대한피부과학회 1998 大韓皮膚科學會誌 Vol.36 No.1
Background: There is concem about the rising incidence of skin cancer. However, few articles have reported the change in the clinical and epidemiological aspects of skin cancer. Objective : We performed this study in order to clarifiy the recent changes in cutaneous premalignant and malignant lesions. Methods : A statistical analysis was made using 101 cases of cutaneous premalignant lesions and 205 cases of ma]ignant tumors out of a total number of 20,175 new outpatients that visited the Department of Dermatology at the Seoul National University Hospital during a 6 year period(1990-1995). Results : The frequency of premalignant lesions was 0.50% and that of malignant tumors was 1.02%. The frequency showed an increasing tendency compared to previous reports. In the premalignant lesion cases, actinic keratosis was most common and represented a figure of 82.2%. Among the malignant tumors, basal cell carcinoma was most frequent at 24.4%. Age, sex and anatomical site distribution of basal cell carcinoma, malignant melanoma was no different. The mean age of squamous cell carcinoma was greater than in previous reports and main preceding lesions were actinic keratosis and cheilitis. The frequency of lymphoma was markedly increased but the reason for this remains to be determined. Conclusion: Our findings showed the continous increasing incidence of skin cancers and emphasize the need for public eduacation, early diagnosis and proper treatment. (Korean J Dermatol 1998;36(1): 7-15)
정혜정 ( Hye Jung Jung ),김경호 ( Kyung Ho Kim ),윤재일 ( Jai Il Youn ),박미연 ( Mi Youn Park ),안지영 ( Ji Young Ahn ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.6
Department of Dermatology, National Medical Center, Seoul, Korea Atopic dermatitis and psoriasis are common, chronic inflammatory skin diseases. They are mediated by different subsets of Th cells (Th1 vs. Th2), so they are believed to be mutually exclusive. However, they have many similar features. Both show epidermal hyperplasia, aberrant immunity, and skin barrier anomalies. We describe the case of an 11-year-old girl with concomitant psoriasis and atopic eczema. She had atopic dermatitis since infancy and had developed psoriatic plaques a few years later. She was diagnosed with atopic dermatitis and psoriasis, and was treated with cyclosporine. Here, we present this case, with a literature review. (Korean J Dermatol 2014;52(6):417∼420)
얼굴 모공 분포와 모공에 영향을 미치는 요인에 관한 연구
정혜정 ( Hye Jung Jung ),서현이 ( Hyun Yi Suh ),심주현 ( Joo Hyun Shim ),이갑석 ( Kap Sok Li ),안지영 ( Ji Young Ahn ),박미연 ( Mi Youn Park ),홍창권 ( Chang Kwun Hong ),윤재일 ( Jai Il Youn ),김범준 ( Beom Joon Kim ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.12
Background: Pores are the openings of the pilosebaceous unit or the apocrine gland. Increase in pore size or in the number of dilated pores may be a cosmetic problem. To date, epidemiological studies on the numbers of dilated pores have been rarely reported. Objective: To analyze the distribution of pores and the factors affecting pores. Methods: We compared the number of dilated facial pores on the face according to site, age group, and sex. The relations of pore counts to wrinkle severity and to the amount of hydration were also analyzed. DermavisionTM, a device that can take cross-polarization, parallel polarization, and ultraviolet light images, was used. Parameters were measured at three points: the forehead, cheek, and nose. Results: The results revealed that dilated pores were more common on the nose and forehead. The pore counts were increased with age, and the increment was significant between participants in their 30s and 40s. Moreover, dilated pore counts were affected by wrinkle severity. The amount of hydration did not affect the counts of dilated pores. Conclusion: In this study, the number of dilated pores differed depending on the location. Moreover, it was confirmed that pore counts were higher in older persons. The pore counts showed a correlation with wrinkle severity. (Korean J Dermatol 2014;52(12):851∼857)