린과 6시그마 통합방법에 관한 실증연구

유선우(Seon-woo You),안 영 진(Young-jin Ahn) 한국생산관리학회 2009 韓國生産管理學會誌 Vol.20 No.3

최근 6시그마 활동을 통해 완성된 고품질의 제품과 서비스를 고객이 원하는 때에 더욱 빠르게 전달하고자 하는 노력으로 린(Lean)방식의 활용이 증가하고 있다.6시그마(SixSigma)와 린의 통합 활용은 “린6시그마(LeanSixSigma)”라는 새로운 용어를 만들어 내었으며,각각의 두 방식이 갖는 장점을 결합하여 더 강력한 경영개선 도구로 활용되고 있다.본 연구는 린과 6시그마에 대한 이론적 고찰을 바탕으로 린6시그마의 성공요인을 통해 기업에서 실질적으로 린6시그마를 추진하는 리더들을 대상으로 실증적인 연구를 하였다.이를 통하여 린6시그마를 활용하고 있는 기업과 경쟁력 강화를 위하여 새롭게 린6시그마의 활용을 검토하고 있는 기업에 대하여 린6시그마의 효율적이고 성공적인 추진을 위한 올바른 방향을 제시하고자 한다. Recent utilization of the Lean system has seen increased efforts to quickly supply completed high quality products through Six Sigma activity.Six Sigma and Lean have integrated uses and a new term,"Lean Six Sigma,"has been coined.The merits of each method are combined and used as an enhanced management improvement tool.In this research,the primary factor for the success of Lean Six Sigma was deduced based on theoretical considerations and an empirical study was conducted on leaders who practically process Lean Six Sigma.An appropriate direction is suggested for the effective and successful implementation of the strategy for companies that are using Lean Six Sigma to strengthen competitiveness and for other companies that are newly examining the use of Lean Six Sigma.

자동분석기를 이용한 분진자극 폐포 대식세포배양 상층액에서 LDH 정량

유선우 ( Seon Woo You ) 대한임상검사과학회 2002 대한임상검사과학회지(KJCLS) Vol.34 No.2

Asbestos is a complete tenn for the mineral fibers that exist in nature. Following the advancement of industrialization, while the use of asbestos has increased and subsequently causes asbestosis, and lung cancer due to exposure to it for extensive periods of time, a man-made mineral fiber was developed to replace asbestos. However, the man-made mineral fiber has similar physical and chemical characteristics with asbestos so it must be considered with respect to hea1th hazard. Therefore, this study shows the cell virulence of silica, asbestos and man-made mineral fibers by adding the dust at the dose of 10, 20, or 100 ug/me to an alveolar macrophage for 1 to 3 days. We then measured the amount of LDH with an auto-analyzer and tried to find the toxicity. of silica, asbestos and man-made mineral fibers that effect the human body. According to the results, si1ica, asbestos and man-made mineral fibers showed a similar increase of LDH with 10, 20, or 100 ug/me until 2 days, even though it was irregu1ar from 3 days. The increase of LDH was indicative of the cytotoxicity of these fibers.

건강진단결과 혈청 AFP와 CEA치 이상자들의 간기능검사 결과 벼교

유선우 ( Seon Woo You ),이광근 ( Kwang Keun Lee ),박효순 ( Hyo Soon Park ) 대한임상검사과학회 2001 대한임상검사과학회지(KJCLS) Vol.33 No.2

Background : Authors investigated the abnonnal rates for serum AFP and CEA amongthe subjects on health screening tests in Kangbuk Samsung Hospital from March, 2000 to October, 2000. And the liver function test resu1ts were analyzed in patients with abnormalserum AFP and CEA. Primary study subjects were 47,042 (male; 28,633, female; 18,409) for serum AFP and 37,847 (male; 23,052, female; 14,795) for serum CEA. Methods Serum specimen from the subjects were analyzed with two-site sandwich immunoassay using ADVIA Centaur instrument (Bayer Corporation, USA). Results : The abnonnal rate for serum AFP was 0.60% (280/47,042) and that of serum CEA was 0.41 % (1 55/37,847). There were no significant six-differences in abnormal rates for serum AFP and serum CEA; male population showed higher abnormal rate (0.65%) for AFP than female (0.51 %) (p=0.056); male also showed higher abnormal rate (0.47%) for CEA than in female (0.31 %) (p=0.016). Among patients with abnonnal test results, the serum AFP level was 77.8 ::t 66O.8 ng/mL and their level of GOT level were 44.5 ::t 77.6 IU/L, GPT 55.0 ::t 134.9 IU/L, ALP 175.1 ::t 61.2 IU/L, Y -GTP 42.6 ::t 113.8 IU/L respectively. The serum CEA level was 6.3 ::t 4.6 ng/mL and their level of GOT 26.0 ::t 14.9 IU/L, GPT 31.2 ::t 27.5 IU/L, ALP 172.6 ::t 45.4 IU/L, y -GTP 31.3::t 36.2 IU/L respectively. Conclusions There were no significant positive or negative relationship among chemical tests for liver function and tumor markers of AFP and CEA, and therefore the prudence should be applied when interpreting these test results.

건강진단 수검자의 B형 간염 표면항원 및 항체 양성률에 관한 연구

유선우 ( Seon Woo You ),이광근 ( Kwang Keun Lee ),박효순 ( Hyo Soon Park ) 대한임상검사과학회 2000 대한임상검사과학회지(KJCLS) Vol.32 No.3

Positive rates for hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) reflect not only the disease status of hepatitis but also general level of hygiene. And Korea has long been the endemic area of the disease. Since the introduction of vaccination for hepatitis B in 1980``s, the positive rates for HBsAg and anti-HBs changed significant1y. To analyze the current status of these paramneters, authors investigated the positive rates for HBsAg and anti-HBs in the subjects on health screening tests in Kangbuk Samsung Hospital from January,1999 to October, 1999. Study subjects were 74,580 (male; 47,470, female; 27,110) for HBsAg and 69,197 (male; 43,624, female; 25,573) foranti-HBs. Serum specimen from the subjects were analyzed with enzyme immunoassay (EIA) using OMNI insσument (Bio-TEK Ins. Inc., Vermont,USA) and Bi∞lisa reagents (Biokit, Barcelona, Spain). The positive rate for HBsAg was 3.85% (2,87이74,580) and that of anti-HBs was 74.70% (51 ,690/69,197). There were significant differences between sex in positive rates for HBsAg and anti-HBs; male population showed higher positive rate (4.41 %) for HBsAg than female (2.87%) (p<0.001); female showed higher positive rate (80.29%) for anti-HBs than in male (7 1.42%) (p<0.001). our results showed lower positive rate for HBsAg and higher positive rate for anti-HBs compared with pre、rious reports. In conclusion, the positive rate for HBsAg declined and that of anti-HBs increased and there were significant difference in positivity of HBsAg and anti-HBs between male and female.

Wako and Daiichi의 Direct HDL-C 비교검토

유선우 ( Seon Woo You ),박창봉 ( Chang Bong Park ),금동극 ( Dong Geuk Keum ) 대한임상검사과학회 1997 대한임상검사과학회지(KJCLS) Vol.29 No.1

3세대 효소면역측정법에 의한 건강진단수검자의 C형 간염 항체 양성율에 대한 연구

유선우 ( Seon Woo You ),이광근 ( Kwang Keun Lee ),박효순 ( Hyo Soon Park ) 대한임상검사과학회 2002 대한임상검사과학회지(KJCLS) Vol.34 No.2

The detection of an antibody to the hepatitis C virus (anti-HCV) by a third-generation enzyme-linked immunosorbent assay (ELISA) posed a problem of false positive results since the inception of the assay. As the generation of the assay proceeded, the false positive rate decreased. We investigated the positive rate by third generation ELISA tests among visitors for health screening and the concordance rate with the western blot method. Positive rates for anti-HCV were investigated with subjects of health screening tests in Kangbuk Samsung Hospital from November, 2α)() to October, 2001. πle study included 10,191 subjects (male; 7,039, female; 3,152). A Serum specimen from the subjects was analyzed using a DONG-A HCV 3.0 kit (Dong-a Pharmaceutical Co., Ltd., Korea). For a confmnatory test, HCV BLOT 3.0 (Genelabs Diagnostics Pte Ltd., Singapore) was used for Western blot in 22 anti-HCV positive samples. πle positive rate for anti-HCV was 0.22% (22/10,191). There were no significant sex. iifferences in the positive rate for anti-HCV; the male population showed a lower positive rate, 0.18% (13/7,039), for anti-HCV than females, 0.29% (9/3, 152) (p=O.3 ll). In the 22 anti-HCV positive samples. 9 showed positive, 7 indeterminate, and 6 negative resu1ts by the HCV BLOT 3.0 kit. πle concordance rate between DONG-A HCV 3.0 and HCV BLOT 3.0 was 72.7%. The third-generation ELISA test by DONG-A HCV 3.0 showed relatively good resu1ts in concordance rate with a confmnatory test by HCV BLOT 3.0. As the discordance sti11 exists between methods, we recommends confmnatoη tests for samples with positive resu1ts on third generation ELISA tests.

순음청력검사에 대한 기본적 이해

민미식 ( Mi Sik Min ),유선우 ( Seon Woo You ) 대한임상검사과학회 2001 대한임상검사과학회지(KJCLS) Vol.33 No.2

Pure-tone audiometry is the most common measure of hearing sensitivity. Stimuli are pure tones at octave frequencies from 250Hz up to 8,αX>Hz and usually two interoctave frequencies(3000Hz and 6000Hz). Pure-tone audiometry should always be carried out with the patient in a double-walled, sound treated room. Test results are graphed on an audiogram. All audiogram include a graph for plotting hearing threshold levels(HTLs). Masking is the audiometric technique used to eliminate participation of the nontest ear whenever air- and bone-conduction stimulation exceeds interaural attenuation. Selection of appropriate masking is difficult, especially when there is bilateral hearing impairment. Type of hearing loss, determined by comparison of the hearing thresholds for air- versus bone-conduction signals, is useful in classifying a hearing loss as sensoryneural(no air-bone gap), conductive(normal bone conduction and a loss by air conduction), or mixed(loss by bone with a superimposed air-bone gap).

생리학 검사실에서 근무하는 임상병리사들의 실태연구

이창희 ( Chang Hee Lee ),유선우 ( Seon Woo You ),이종대 ( Jong Dae Lee ) 대한임상검사과학회 2002 대한임상검사과학회지(KJCLS) Vol.34 No.2

We designed a questionnaire to use as the basic materials for the position of Medical Technologist(MT) in the hospital and exposure of infection in the Clinical Electrophysiologic Laboratoη. Also, it will be used to eliminate medical services of the un1icensed in the Clinical Electrophysiologic Laboratory. ’The contents of the questionnaire, performed from 29, January to 15, March 2002, are about a working period of an MT in the Clinical Electrophysiologic Laboratoη, one’s place, one’s opinion about a professional MT and one’s infection control. In working conditions 57.8% work in only one laboratory, 39.4% in rotation in one department and the rest(2.8%) cycle between all. In the necessity of a professional MT, most of the people are positive (95.4%). About a professional MT in each field, 84.4% of the subjects gave their approval. In their position, 67.9% of the subjects are under the control of Clinical Services, 22% in the Clinical Electrophysiologic Laboratory and others (10.1 %) belong to the department of Clinical pathology. All PFfs, ECGs, and EEGs are examined by the MT but in case of TCDs (59.7%) and TMTs (71.6%) most of the examinations are performed by a licensed or non-MT (doctor, nurse). In case of infection control, most of the hospitals (96.6%) have a Committee of Infection Control. According to the questionnaire, in most hospitals, the unlicensed or non- MTs are engaged in the Clinical Electrophysiologic Laboratory. Also, in the field of labor, infection control is neglected and there is not preventable instructions about it. Thus we should make every effort continuously to minimize infection and improve working conditions.

녹색물류 진단방법과 녹색물류 효율화 방안

김택수(Taek-Soo Kim),박재원(Jae-Won Park),유선우(Seon-Woo You) 한국구매조달학회 2010 한국구매조달학회지 Vol.9 No.1

산업화의 가속화에 따른 자원 고갈의 문제와 기후변화에 따른 환경보호의 인식 증가는 기존 경제의 패러다임에 대한 변화를 요구하고 있다. 기후변화의 가속화에 따라 국제사회는 탄소배출량을 강제하는 논의를 활발하게 진행하고 있으며, 선진국을 중심으로 각국의 정부에서도 녹색 관련 정책을 우선하여 시행하고 있는 실정이다. 이에 따라 원재료에서 최종제품이 소비자에게 전달되는 과정에 대한 물류관리활동에 있어서 탄소 배출을 효율적으로 관리할 수 있는 녹색물류 환경 구축의 중요성이 증가될 전망이다. 본 연구에서는 녹색물류 진단방법과 적용사례의 고찰을 통하여 녹색물류 효율화 방안을 제시하였다. According to the acceleration of industrialization the problem of resources depletion is increased. Also the environmental protective clothing recognition is increasing about change in climate. The international community is to strengthen a regulation about carbon discharge volume. The advanced nations are the actual condition which enforces green relation policy with a precedence. Now, green concept is necessary situation in logistics activity. According to this, efficient management’s necessity is increasing about carbon discharge. This research presented efficient green logistics management way through green logistics diagnosis method and application instance.

신장질환 환자에서 혈청과 요단백 전기영동 분획 평가

임현진 ( Hyun Jin Lim ),백승옥 ( Seong Ok Back ),이범희 ( Bum Hee Lee ),유선우 ( Seon Woo You ) 대한임상검사과학회 2006 대한임상검사과학회지(KJCLS) Vol.38 No.2

One of the cardinal findings of the renal diseases is proteinuria, which appears in the early phase of kidney diseases and is very important in diagnosis, prognosis and decision making in the treatment process and results of the treatment. The study subjects were 126 patients who visited the nephrology department of Kangbuk Samsung Hospital. Serum was requested for urine protein electrophoresis. Total protein was measured with Bayer Advia 1650 (Biuret). Quantitation of each fraction was done by multiplying the percentage of each fraction by the total protein. Serum creatinine and BUN were also measured with Bayer Advia 1650 (Jaffe and Urease). Serum protein EP was done with REP(rapid electrophoresis) using Helena Kit reagents (REP Ultra SPE Kit, Ponceau S stain, Acetic acid, Methanol, EP Control). Concentrated urine was used for urine protein EP. The SPSS package was used for statistics analysis. Percentage and quantitation of the level of albumin in renal diseases were significantly lower than those in healthy controls. Total protein was correlated with albumin. In terms of proportion, α1-globulin, α2-globulin, β-globulin, and γ-globulin fractions were increased in the disease group. But, in the quantified level, α2-globulin was increased and β -globulin and γ-globulin were decreased. ESRD patients showed an increased secretion of high molecular proteins in urine protein EP. A decreased level in serum total protein correlated with the decreased level of serum albumin and the total amount of urine total protein. This study revealed the variety in the level of serum and urine proteins and their subgroups by EP.