아크릴의 전기방사시 방사조건이 웹 형성에 미치는 영향

심현주,이승훈,Shim Hyun Joo,Lee Seung Hoon 한국섬유공학회 2004 한국섬유공학회지 Vol.41 No.6

The electro-spinning conditions, such as, concentration of polymer solution, electric potential, die to collector distance(DCD), electric conductivity of collector, and additives on the change of fiberweb structure and fiber diameter, have been investigated. The results showed that the electric potential and die to collector distance affect the fiber diameter and the fiberweb uniformity. The difference of the electric conductivity of collector and the additives did not affect the fiber diameter, however, the uniformity of the fiberweb was significantly affected. The optimum spinning conditions for the electrospinning of polyacrylonitrile were found as follows; the electrical potential should be in the range of 25 to 30 kV, the DCD 15 cm, and the concentration of polymer solution should be between 12 to $15\%$.

원심력을 이용한 세사 제조의 새로운 방식

심현주,Shim, Hyun-Joo 한국섬유공학회 2010 한국섬유공학회지 Vol.47 No.5

There are several ways for producing fine denier fibers, such as conjugate spinning, melt blowing, electro-spinning, etc.. Each of these methods has its own merits and demerits. A new technology for manufacturing micro fibers was devised. The idea of this equipment was to apply a centrifugal force on the molten polymer to elongate the spun fiber. The angular velocity of the spinneret, nozzle hole diameter, and melting temperature were controlled to determine their effects on the fiber diameter. The results showed that <0.1 denier fibers could be produced swiftly and economically. The simple machine design enables the operator to access the machine with little or no experience in fiber spinning, and leads to an almost maintenance-free machine compared to other spinning apparatuses.

멜트블로운 부직포의 정전 처리조건이 여과효율에 미치는 영향

심현주,강준영,장선호,오태환,Shim, Hyun-Joo,Kang, June-Young,Jang, Sun-Ho,Oh, Tae-Hwan 한국섬유공학회 2008 한국섬유공학회지 Vol.45 No.2

The air filter media were prepared using light polypropylene melt- blown nonwovens and then, corona charge was applied to achieve with low pressure drop and high filtration efficiency air filter. The processing variables for the corona treatments were set up, such as, the electric potential distance between the electrode and the nonwoven, the number of charging, the sequences of charging surfaces, and the concentration of ferro-dielectric nano particles. The electrical potential was applied in the range of 15 to 35 kV, the number of charging was 1 to 4 times with and without turn over the charging surface, the concentration of ferro-dielectric nano particle solutions were 0.5 to 1.5% (W/V). In this research, the most probable processing conditions gave a clue to make a HEPA filter when the media was plied 5 times. This HEPA filter showed its initial pressure drop be 7.7 mmAq and filtration efficiency be 99.99%.

정신건강의학과 환자안전사고 분석(2017-2021)

심현주(Hyun Joo Shim),홍은영(Eun Young Hong) 안전문화포럼 2023 안전문화연구 Vol.- No.25

본 연구는 국내 의료기관 정신건강의학과 환자에서 발생한 환자안전사고 발생 현황과 위해 수준을 파악하고 위해 발생에 영향을 주는 요인을 확인하여, 추후 정신건강의학과 환자의 안전사고 예방을 위한 전략 마련의 기초자료를 제공하고자 실시하였다. 의료기관인증평가원에서 전국적으로 수집하여 공개하고 있는 환자안전통계데이터를 활용하여 200병상 이상 종합병원과 상급종합병원의 세부 진료과목이 정신건강의학과로 분류되어있는 총 521건을 분석하였다. 자료 분석은 SPSS/WIN 27.0 프로그램을 사용하여 기술통계, 교차분석, 이항 로지스틱 회귀분석을 실시하였다. 그 결과 연도별 환자안전사고 건수는 2017년에 비해 2020년, 2021년에 조금 증가하였으며, 환자안전사고의 위해수준은 2017년에서 2021년으로 갈수록 근접오류가 증가하고 위해사건은 감소하는 경향을 보였다. 종합병원이 상급종합병원에 비해 환자안전사고의 위해 사건 비중이 더 유의하게 높았다. 이항 로지스틱 회귀분석 결과 종합병원이 상급종합병원에 비해 위해 발생위험이 2.459배 높았고, 사고종류 중 투약오류와 비교하여 낙상은 위해 발생위험이 10.677배, 자살 및 자해 사건은 위해 발생위험이 66.103배 높았다. 연령대별로는 0~19세에 비해 20~39세의 위해 발생위험은 3.335배였고, 40~59세의 위해 발생위험은 4.911배, 60세~79세의 위해 발생위험은 5.340배, 80세 이상의 위해 발생위험은 4.027배였다. 최종모형의 적합도 검정결과 적합한 것으로 나타났으며(Hosmerand Lameshow test χ2=5.598, p=.302), 설명력은 30.2%였다(Nagelkerker R2=.302, χ2=116.241, p<.001). 추후 종합병원의 간호 인력 수준과 환자안전사고 발생에 관한 체계적 분석이 필요하며, 정신건강의학과 환자안전사고 예방대책 수립시 종합병원을 우선 적용대상으로 포함해야 하며, 자살 및 자해 예방, 낙상 예방전략을 필수적으로 포함해야 할 것이다. 또한, 60~79세 대상자에게 환자안전사고 예방전략을 우선적으로 적용해야 할 것으로 사료된다. The study was undertaken to investigate the occurrence and risk levels of patient safety incidents in the mental health department of domestic medical institutions, aiming to provide essential data for formulating strategies to prevent such incidents in the future. The data for this study were collected nationwide from medical institutions accredited by the Korean Institute for Healthcare Accreditation, with a focus on patient safety statistics. A total of 521 cases from comprehensive and tertiary hospitals with more than 200 beds, classified under the department of mental health and psychiatry, were analyzed. Data analysis was performed using SPSS/WIN 27.0 software, encompassing descriptive statistics, cross-tabulation analysis, and binary logistic regression. The results showed that the number of patient safety incidents increased slightly in 2020 and 2021 compared to 2017. However, the level of harm caused by these incidents indicated a trend of increasing near misses and decreasing adverse events from 2017 to 2021. Comprehensive hospitals had a significantly higher proportion of adverse events in patient safety incidents compared to tertiary hospitals. The results of binary logistic regression analysis revealed that comprehensive hospitals had a 2.459 times higher risk of adverse events compared to tertiary hospitals. When comparing incident types, the risk of adverse events for falls was 10.677 times higher, and for suicide and self-harm events, it was 66.103 times higher compared to medication errors. Regarding age groups, the risk of adverse events for the 20-39 age group was 3.335 times higher compared to the 0-19 age group. For the 40-59 age group, the risk was 4.911 times higher for the 60-79 age group, it was 5.340 times higher, and for the 80 years and above age group, it was 4.027 times higher . The goodness of fit test for the final model indicated a good fit, and the model's explanatory power was 30.2%. Based on the study results, there is a need for a systematic analysis of nursing staff levels in comprehensive hospitals and their relationship with patient safety incidents and it is crucial to prioritize comprehensive hospitals when devising patient safety incident prevention measures in mental health. Suicide and self-harm prevention, and fall prevention strategies, should be considered as indispensable components. Furthermore, it is recommended to give priority to implementing patient safety incident prevention strategies for individuals aged 60-79 years of age.

뚜껑이 없는 이동섭자(transfer forcep) 교환주기에 관한 연구 : 일 종합병원을 중심으로

심현주(Shim Hyun Joo),홍은영(Hong Eun Young) 사단법인 안전문화포럼 2021 안전문화연구 Vol.- No.13

본 연구는 A병원 내 16개 부서에서 뚜껑이 없는 이동섭자(긴 섭자와 섭자통)를 개봉하여 사용하기 시작한 시점으로부터 8시간까지 시간대별로 미생물이 자라는지 검사하여 이동섭자의 적절한 교환주기를 확인하고자 시도되었다. 또한 본 연구를 통해 추후 관련 연구를 위한 기초자료를 제공하고 감염관리 및 멸균물품 관리를 위한 근거를 확인하기 위한 목적으로 시도되었다. A병원 내 일반병동 전수인 10개 부서와 특수부서 전수인 응급실, 내과중환자실, 신생아중환자실, 분만실의 4개 부서와 외래부서 중에서 이동섭자를 주로 사용하는 부서인 피부과 외래와 성형외과 외래 2곳을 포함한 총 16개 부서가 포함되었다. 부서별로 멸균된 이동섭자 개봉 직후 및 개봉 이후 1시간 간격으로 8시간까지 총 9회에 걸쳐 이동배지를 이용하여 검체를 채취하고 미생물배양 검사실에서 37℃의 배양기에서 3일간 배양하여 미생물배양 여부를 확인하였다. 그 결과 일반병동 10개 부서와 특수부서 4개 부서와 외래부서 2곳 모두에서 멸균된 이동섭자 개봉 직후 채취한 검체에서 어떤 균주도 동정되지 않아 음성이었다. 또한, 실험이 진행된 16개 부서 모두에서 개봉 이후 병원 내에서 실제 사용하는 장소(처치실, 진료실 등)에 두고 1시간에서 8시간까지 한 시간 간격으로 이동배지를 이용하여 채취한 검체를 3일간 배양한 결과 어떤 균주도 동정되지 않아 음성이었다. 본 연구는 의료기관에서 가장 기본적으로 사용하고 있는 의료기구 중 하나인 이동섭자의 교환주기와 관련된 최초의 연구로 의의가 있으며, 추후 표준화된 관리방법이나 교환주기에 대한 지침을 마련함으로써 다양한 연구의 기초자료로 활용될 수 있을 것으로 기대된다. 이러한 임상단위의 현장연구 결과를 통해 표준화된 매뉴얼을 구축한다면 의료기관의 업무혼선 완화, 반복연구로 인한 비용 감소와 의료관련감염 예방 및 효율적 감염관리체계 수립에 이바지 할 수 있을 것으로 사료된다. 또한, 추후 의료인이 실제 사용하는 이동섭자에서 오염 발생 여부를 확인하는 연구를 추가로 수행할 것을 제언한다. 본 연구는 1개의 병원에서 이루어진 연구로 일반화에 제한이 있으며, 다양한 환경적 영향요인 파악에 한계를 지닌다. The purposes of the study was determination of the exchange cycle of transfer forcep through taking samples from right after to 8 hours after opening of sterile transfer forcep packs for every hour from 16 departments of A hospital. Also, the purpose of this study were to provide the basic data for relate further researches and contribute to prevention of healthcare-associated infection and confirm the evidence of the menagement for sterile medical supplies through determination of the exchange cycle of transfer forcep. This research was performed in 10 general ward, emergency room, medical intensive care unit, neonatal intensive care unit, delivery room, dermatology outpatient department and plastic surgery outpatient department. Specimens were obtained from right after to 8 hours after opening of sterile transfer forcep packs for every hour from each 16 departments of A hospital using transport medium. Two researchers took samples using transport medium and incubated for three days in 37℃ incubator of mictobiological laboratory of A hospital. The results from specimens obtained right after opening of sterile transfer forcep packs from 16 departments were all negative. Also the results from specimens obtained from 1 hour to 8 hours after opening of sterile transfer forcep packs from 16 departments were all negative. Transfer forceps were kept on sterile for 8 hours after unpacked. This study is meaningful as the first resaerch about exchange cycle of transfer forcep and the results of the study can be used as basic data for the study related to exchange cycle of transfer forcep and standardized guidline development related to transfer forcep. Also, the result of this study can be used as a basic data to build effective healthcare-associated infection control system. Further reaearch is recommanded to testify of contamination of transfer forcep which is used in clinical by healthcare providers. The results of this study have limitations in generalization and consideration of environmental effect.

삼각사와 원형사로 제직된 직물의 태, 열적성질 및 광학적 성질의 비교

심현주 ( Hyun Joo Shim ),홍경아 ( Kyoung A Hong ) 한국감성과학회 2002 감성과학 Vol.5 No.3

Recombinant Human Erythropoietin (DA-3285) 의 실험동물에서의 약동력학 및 조직분포

심현주(Hyun Joo Shim),이응두(Eung Doo Lee),이종진(Jong Jin Lee),김흥재(Heung Jae Kim),이상득(Sang Deuk Lee),이성희(Sung Hee Lee),김원배(Won Bae Kim),양중익(Junn Ick Yang) 한국응용약물학회 1996 Biomolecules & Therapeutics(구 응용약물학회지) Vol.4 No.1

The pharmacokinetics and tissue distribution of DA-3285 (recombinant human erythropoietin, recently manufactured by Research Laboratories of Dong-A Pharmaceutical Company) were studied in the laboratory animals. The plasma, urine, and tissue concentration of DA-3285 were measured by a double-antibody sandwich enzyme immunoassay. After intravenous administration of DA-3285, 20, 100, 500 and 2500 units/㎏ to rats, the plasma concentrations declined polyexponentially with the terminal half-lives of 2.15, 2.10, 2.31, and 2.35 hr, respectively. Total body clearance (20.7∼26.6 ㎖/hr/㎏) and apparent volume of distribution at steady state (57.2∼70.1 ㎖/㎏) were independent of the dose and AUC increased proportionally with the dose. The renal clearance was much lower than total body clearance, suggesting that extrarenal clearance, presumably metabolism , plays a significant role in elimination of DA-3285. In all rat tissues, the tissue to plasma ratios were smaller than unity, indicating less affinity of DA-3285 to rat tissues and was proved by considerably less value of Vdss. After 3 times a week for consecutive 3 weeks i.v. administration of DA-3285, 100 units/kg to rats, the plasma concentrations and pharmacokinetic parameters of DA-3285 were not significantly different from those in a single administration. After s.c. administration to the rat, plasma concentrations of DA-3285 peaked at 6 hr and the extent of bioavailability was 26.7%. In mice, rabbits and dogs, at DA-3285 dose of 100 units/kg, the mean terminal half-lives were 2.78, 3.05, and 4.01 hr, respectively. Compared with reported data in the literatures, DA-3285 has similar properties to rh-EPO manufactured by other companies in view of pharmacokinetics.

직물 구성사의 단면구조가 수분전달에 미치는 영향

홍경아,심현주,Hong Kyoung A,Shim Hyun Joo 한국섬유공학회 2005 한국섬유공학회지 Vol.42 No.1

In order to investigate the effect of fiber cross-sectional shape and fiber assembly structure on water transmission property of a woven fabric, various types of ]ion-circular fibers were prepared. Two yarns of different total denier, and yarns of different cross-sections were used To compare the fabric properties more rigorously, the fabrics were woven in the same weaving loom under identical weaving conditions, except changing the weft yarns as mentioned above. To clarify the effect of fiber cross-section:11 shape on the water transmission properties of fabrics, vertical wicking strip test and GATS(gravimetric absorbency to testing system) were used. The absorbance of fabrics were measured by means of GATS. The vertical wicking height in fabric woven from U shaped yarn having lots of pore was higher. The amount of water transmission in fabric made of H/_Y shaped yarn was grater. For H/_Y shaped yarns, fabric has more spaces due to the different fiber density and cross-sectional shapes.

방화복의 내구특성 변화에 관한 연구(I) - 국내 화재진압에 사용한 소방복의 성능변화 -

김도식,심현주,Kim, Do-Sik,Shim, Hyun-Joo 한국섬유공학회 2008 한국섬유공학회지 Vol.45 No.6

It has generally been recognized that the fire protective cloth is one of the most important fire extinguishing equipments because it governs the efficiency of fire suppression as well as the safety of fire fighter's life. There are diverse circumstances in a blazer, thus, the protection functions from these dangers are the basic requirements of fire protective cloth. The fire protective cloth needs barrier functions from external heat, mechanical hazards, toxic chemicals, and so on and also needs the emission functions of wearer's body heat and sweat. When the cloth is worn repeatedly in the fire extinguishing field, it should be damaged and could not work properly in the long run. However, the fire protective cloth is very expensive and cannot be accommodated so frequently. For this purpose, this research was done as a part of work to set up the life time of the fire protective cloth. To evaluate the durablility, the change of mechanical properties the fire protective cloth worn by fire fighters for one year in the fire extinguishing field were compared with the new one. The tensile properties of the outer fabric of the cloth were damaged mostly by radiant heat and day light, however, the water proof properties of mid layer were reduced by repeated bending and washing. The decline of fabric physical properties of radiant heat was greater under wet state than under dry state.

나노 입자 첨가에 따른 정전 멜트블로운 부직포의 여과효율에 관한 연구

장선호,심현주,Jang, Sun-Ho,Shim, Hyun-Joo 한국섬유공학회 2008 한국섬유공학회지 Vol.45 No.5

We designed a filter media which could collect of submicron size particles by applying electrostatic charge. To meet our proposed design, three different types of nano-scaled materials such as nonconductor ($SiO_2$), conductor ($Al_{2}O_{3}$), ferroelectric material ($BaTiO_3$) were incorporated into the melt-blown nonwovens made of micro fiber. Polypropylene melt-blown nonwovens, basis weights of $15\;g/m^2$ and $20\;g/m^2$, were prepared. The nano particles were diffused in the ethanol and then the electro sprayed on the nonwoven fabrics to be uniformly dispersed. The specimens containing nano particles were conditioned for three hours in the vacuum drying oven. To meet our purpose, the specimens were corona charged to develop the static electricity. The charging density and filtration efficiency of the filter media were investigated with various experimental conditions: such as types of additives and their concentrations. It was shown that the charging density and filtration efficiency were increased with increasing the basis weight of the samples. The filter media incorporated with ferroelectric particles showed the most desirable results compared with the other two additives.