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허승재(S.J.Huh),하성환(S.W.Ha),박찬일(C.I.Pack),최국진(K.J.Choi),김진복(J.P.Kim) 대한방사선종양학회 1984 Radiation Oncology Journal Vol.2 No.2
Surgery remains the mainstay in the management of carcinoma of the rectum. However, local recurrence and systemic metastasis remain the challenge. It appears that post operative radiotherapy has a very definite role in the reduction of local recurrence. Ninty two patients of carcinoma of the rectum after curative surgery received post operative radiotherapy 5,000 rad/5~6weeks to whole pelvis at the Department of Therapeutic Radiology, Seoul National University Hospital between March 1979 and December 1982. Fifty three percent of patients show modified Astler-Coller stage C₂. Actuarial disease free survival rate of rectal cancer was : stage B1,2 75% stage C1 81% stage C₂ 39%, and stage C₃ 20%. Twelve percent shows local recurrence and distant metastasis occurred in 28%. Prognostic sighificance of nodal metastasis is also analysed. Incidence of small bewel obstruction, requiring surgery, is 8%. occurring between 5th month to 12th month after operation. It is suggested that post operative radiotherapy of the rectal cancer following curative surgery has a signifinat role in the reduction of local recurrence.
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조문준(M.J. Cho),하성환(S.W.Ha),박찬일(C.I.Pack),김락경(N.K.Kim) 대한방사선종양학회 1984 Radiation Oncology Journal Vol.2 No.2
The recogition that the vast majority of patients with small cell lung cancer have distant metastatic disease at the time of diagnosis lead to the use of systemic chemotherapy and consequent major improvement in survival, but recently evaulated treatment strategies, integration of large field chest irradiation with chemotherapy lead to the improved the local control and relapse free survival in limited SCLC. Therefore, it is logical to combine the two modalities in an effort to maximize the therapeutic effect. Authors performed the combination chemotherapy of CAV(Cyclophosphamide, Adriamycin, and Vincristine) and radiotherapy of primary tumor and regional lymphatics with prophylatic cranial irradiation in 42 patients of limited SCLC, from MAR. 1978 to Dec. 1982 Seoul National University Hospital. The results are as follows; 1. CR and PR after 2 cycles chemotherapy is 7% and 43%, respectively however, subsequent response to radiotherapy is 38% and 43% in CR and PR. 2. Overall median survival period is 8.6 months. 3. 1 year and 2 year survival rate is 46.3% and 20.5%, respectively. 4. Incidence of proven brain metastasis is 5%.
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