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담낭신티그라피에 의한 담낭담석증 및 간흡충증 환자의 담낭운동성 분석
정판준(Pan Jun Chung),심대석(Dae Seok Shim),강재황(Jae Hwang Kang),류경렬(Gyeong Yeul Reu),원용환(Yong Hwan Won),박영호(Yung Ho Park),손미정(Mi Jung Son),정순일(Soon Il Chung),이옥재(Ok Jae Lee),김영채(Young Chai Kim) 대한내과학회 1995 대한내과학회지 Vol.48 No.1
N/A Objectives: Abnormal gallbladder motility and bile stasis have been implicated in the pathogenesis of gallstone and bacterial infection, but the cause-and-effect relationship is not established. Among the various methods used to measure the gallbladder motility, cholescintigraphy using 99 mTc-labelled iminoacetic acid is nowadays used widely, which is noninvasive, convenient, and is capable of quantitative analysis of gallbladder motility. To evaluate the gallbladder motility in patients with gallstones and clonorchiasis, the authors analyzed the gallbladder filling and emptying using computer-assisted cholescintigraphy. Methods: The study group comprised 30 patients who were admitted to GNUH, from 1992, October to 1993, August, 20 patients of them had asymptomatic gallbladder stones or clonorchiasis, 10 patients were controls. All patients were studied with abdominal ultrasonography and DISIDA cholescintigraphy. We measured maximum gallbladder filling time, half time of emptying and ejection fraction after ingestion of fatty meal. Results: 1) There was no significant difference in maximum gallbladder filling time between control (52.3±9.3 min) and patients with gallbladder stones (51.5±15.8 min) and patients with clonorchiasis (56.9±10.5 min). 2) Gallbladder emptying time (T1/2) were significantly delayed in patients with gallbladder stones (48.4±16.3 min) and clonorchiasis (40.8±12.9 min), as compared with control (23.0±7.5 min). Conclusion: The gallbladder emptying time using computer-assisted cholescintigraphy in patients with gallbladder stones and with clonorchiasis were significantly delayed, as compared with control.