http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 나운성(Woon Seong Nah) (검색결과 1 건)
- 무료
- 기관 내 무료
- 유료
-
Astaxanthin 함유 기능성 식품소재의 유전독성 및 항산화능 검사
김준성(Jun-Sung Kim),박진홍(Jin Hong Park),김화(Hua Jin),조현선(Hyun Sun Cho),황순경(Soon Kyung Hwang),나운성(Woon Seong Nah),강환구(Hwan Goo Kang),안길환(Gil-Hwan An),조명행(Myung-Haing Cho) 한국독성학회 2006 Toxicological Research Vol.22 No.4
Astaxanthine is a pigment that belongs to the family of the xanthophylls, the oxygenated derivatives of carotenoids whose synthesis in plants derives from lycopene. Astaxanthine is also a carotenoid widely used in salmonid and crustacean aquaculture to provide the pink color characteristic of that. Recent study reported that astaxanthine has the role as a detoxicant against the free radicals. In our study, we estimated the genotoxicity in ICR mice and possibility as antioxidant reagents of mutant Phaffia rhodozyma strain over expressing the astaxanthine by gamma-lay and carophyll pink including astaxanthine in apoE knock out mice, respectively. In our study, we administered Phaffia rhodozyma (2 ㎎ and 3 ㎎) and carophyll pink for 4 and 8 week. The clinical sign and mortality were not detected compared with control groups. In the mutant frequency of hprt gene and chromosome aberration in splenic cells, there was not detected abnormality. There was not critical change in hematological and serum biochemical test compared to control. In expression level of repair enzyme, increase of catalase were detected and increase of expression level of Nrf-2 was detected in Phaffia rhodozyma (3 ㎎) and carophyll pink in 8 week treated group. In GSH level, the group of treated with Phaffia rhodozyma (3 ㎎) showed the increase of the GSH. In conclusion, mutant Phaffia rhodozyma and caphyll pink may be applied to the effective food additives to reduce the free radical.
DBpia
ScienceON연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
