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      • KCI등재

        정상출산부 오로의 임상세균학적 관찰

        김현준(HC Kim),이홍균(HK Lee),양석기(SK Yang),박성구(SK Park) 대한산부인과학회 1973 Obstetrics & Gynecology Science Vol.16 No.4

        본원 산부인과에서 1969년 1월 초부터 동연 3월말 사이 만 3개월간 질식 분만후 12-72시간(평균 39시간)내에 무균조작으로 자궁경관 및 후질궁융뷰에서 채취한 오로를 호기성과 혐기성 조건하에서 혈액한천배지 및 Thioglycollate배지에서 배양한 후 균의 분포를 분석 관찰하였으며 몇가지 항생제에 대한 감수성검사를 Disk방법으로 일부 균주에 대하여 시행하여 다음과 같은 결과를 얻었다. 1) 총 107례 중에서 균이 배양된 례는 101례로 94.3%이었고 배양되지 않았던 례는 6례로 5.7% 이었다. 균이 배양된 경우 2종의 균이 동시에 배양된 예가 제일 많아 36례이었고 단일균이 28례, 3종의 균이 18례, 4종의 균이 16례, 5종의 균이 3례로 각각 동시 배양되었다. 단 1균종이 배양된 28례 중에서는 E.coli가 7례로 가장 많았다. 유산균의 순수 배양례는 1례도 없었다. 2) 배양균들을 그 빈도순위로 보면 Unidentified Gram negative bacilli가 40.2%, Streptococci( -hemolytic, Viridans 포함)가 33.7%, Staphylococci(S. aureus, S. epidermis)와 Lactobacillus species가 각각 19.6%, E.coli가 18.7%, Micrococcus와 Corynebacterium species (Diphtheroids 포 함)이 각각 14.0%, Enterococcus가 10.1%, Coliform bacilli와 Hemophilus species가 각각 6.5%, Yeast like cells 가 4.7%, Unidentified Gram positive bacilli와 Clostridium species 가 각각 3.7%, Neisseria species가 1.9%, Bacterium anitratum, Proteus mirabilis, Klebsiella aerogenes와 Providence group이 각각 0.9%이었다. 3) 배양균의 분포와 제요인 즉 산모의 연령, 분만횟수, 분만방법, 회음절개 및 경관 열창등의 요 인들과의 상호관계를 살펴본 결과 배양균 분포와 밀접한 관계는 찾아 볼 수 없었다. 4) 항생제에 대한 감수성검사에서 각 균주에 대하여 감수성이 있는 항생제는 다음과 같은 것들 이었다. a) E.coli는 전례에서 Neomycin, Ampicillin과 Colistin에 Sensitive하였고 대부분의 경우에 Chloramphenicol과 Streptomycin에 Sensitive하였지만 일반적으로 Kanamycin에는 Moderately sensitive하였다. b) Staphylococcus는 전례에서 Methicillin과 Cloxacillin에 Sensitive하였고 대부분은 Leucomycin 과 Erythromycin에 Sensitive하였지만 일부는 Resistant하였다. c) Enterococci는 대부분 Ampicillin과 Erythromycin에 Sensitive하였고 일부는 Chloramphenicol 과 Neomycin에 Sensitive하고 일부는 Resistant하였다. d) Coliform bacilli는 전례가 Neomycin에 Sensitive하였고 대부분은 Chloramphenicol, Streptomycin, Colistin과 Ampicillin에 Sensitive 하였지만 Kanamycin에는 Moderately sensitive 하였다. e) Clostridium species는 Tetracycline과 Erythromycin에 Sensitive하였다. During the period from January 1 to March 31, 1969, lochia was taken for the bacteriological culture and sensitivity test from 107 patient of normal afebrile postpartum women, aged 20 to 40, who had given birth vaginally at the Dept. of Obstetrics and Gynecology, Naotional Medical Center, Seoul. The specimens were taken aseptically from cervical canal or posterior vaginal fornix within postpartum 12 to 72 hours (Av. 39 hrs.) and then cultured on blood agar or thioglycollate media under aerobic and anaerobic conditions. With cultured several organisms, sensitivity test was done by Disk method to some current antibiotics. The results were obtained as follows: 1. Among 107 cases, culture was positive in 101 cases (94.3%) and sterile cultrue(negative cultrue) was in 6 cases (5.7%). Among the above 101 cases of positive culture, mixed culture of two different bacteria were found the most commonly at the same time in 36 cases, pure culture in 28 cases, mixed culture of three bacteria in 18 cased, four bacteria in 16 cases and five bacteria in three cases. Among the above 28 cases of pure culture of Lactobacillus was sepcies found. 2. the cultured organisms and its incidence in order were as follows; Unidentified anaerobic gram negative bacilli in 40.2%, Streptococci (anaerobic, beta hemolytic and viridans) in 33.7%, Staphylococci (aureus and edpidermis) and Lactobacillus species in 19.6%, respectively, E. coli in 18.7%, Bacteroides in 15.9%, Micrococcus species and Corynebacterium species including Diphtheroids in 14.0%, respectively, Enterococcus in 10.1%, Coliform bacilli and Hemophilus species in 6.5%, respectively, Yeast like cells in 4.7%, Unidentified gram positive bacilli and Clostridium species in 3.7%, respectively, Neisseria species in 1.9%, Bacterium anitratum, Proteus miarbilis, Klebsilia aerogenes and Providence group in 0.9%, respectively. 3. Relationships between the distribution of cultured organisms and several factors such as age, parity, mode of delivery and presence or absence of episiotomy or cervical repair, were analysed. However no remarkable difference in distribution of cultured organisms could be found. 4. The results of sensitivity test (as to the sensitive antibiotics) were as follows; a) E. coli was sensitive to Neomycin, Ampicillin and Colistin in all cases. Most of them were sensitive to Chloramphenicol and Streptomycin. Generally, it was moderately sensitive to Kanamycin. b) Staphylococcus aureus was sensitive to Methicillin and Cloxacillin in all cases. Most of them were sensitive but part of them were resistnat to Leucomycin and Erythromycin. c) Most of Enterococci were snesitive to Ampicillin and Erythromycin but part of them were sensitive or resistant to Chloramphenicol and Neomycin. d) Coliform bacilli were sensitive to Neomycin in all cases and most of them were sensitive to Chloramphenicol, Streptomycin, Colistin and Ampicillin. They were moderately sensitive to Kanamycin. e) Clostridium species were sensitive to Tetracycline and Erythromycin in all cases.

      • KCI등재

        복강경불임술의 임상적 관찰 ( 제1호 )

        박인재(IS Park),김현준(HC Kim),박성구(SK Park),송인철(IC Song) 대한산부인과학회 1975 Obstetrics & Gynecology Science Vol.18 No.3

        저자는 1974년 5월 1일 부터 11월 30일까지 국립의료원 산부인과를 방문한 불임수술희망자중 복강경불임술을 시행한 147명에 대하여 조사분석하여 다음과 같은 결과를 얻었다. 1) 연령분포는 31-35세군이 79례(53.7%)로 수위이었고 26-30세군이 37례(25.2%)로 차위이었다. 11) 합병증으로 난간막출혈 9례, 그리고 피하기종이 3례있었다. One hundred forty seven cases of Laparoscopic tubal sterilization wre performed by means of fulguration and resection under mostly general anesthesia or local anethesia in a small number of caes during 19 months period from May 1 1973 to Nov, 30 1974. One incision and three burn technique were applied in this study. Age distribution showed the highest incidence in the age group of 31 to 35 years and average age was 32.6 years with the youngest age 19 years and the oldest 42. The number of children at Laparoscopic sterilization reported 3 kid in 40.4% of all cases and 2 kids in 23.8% respectively. The interval between the last delivery and Laparoscopic sterilization ranged 1 to 3 years in 45.6% of all cases. General anesthesia was used for 126 caese (82.7%) local anesthesia for 18 cases (12.3%) and combined local and general anesthesia for 3 cases (2.0%) Three to five liters of CO2 gas consumed for pneumoperationeum in more than half of all cases. It took less than 30 minutes to complete Laparoscopic tubal sterilization in 79.0% of all cases. Hospital stay required less than 24 hours in 80.2% of all case mostly in case of general anesthesia. Twelve cases (8.2%) of previous appendectomy were submitted to Laparoscopic tubal sterilization without considerable technical difficulty. Other episodes of previous Laparotomy were excluded for the indication of Laparoscopic tubal sterilization Laparoscopic tubal sterilization coincidence with artificiall abortion were carried out in 63 cases As the complications 9 cases of mesosalphingeal hemorrhage 7 cases of tubal hemorrhage and 3 cases of subcutaneous emphysema were encountered, but no intensive medical care was required in any cases.

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