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김은규(Eun Kew Kim),홍옥련(Oak Ryun Hong),박은선(Eun Sun Park),김은정(Eun Jung Kim),조은나(Eun Na Cho) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.10
Chorioangioma is the most common primary tumor of placenta. The incidence is approximately 1%. These tumors are benign and are not usually associated with clinical sequale unless they are >5cm in diameter. However large tumors are often associated with obstetrical and fetal complications. We recently observed a pregnancy associated with a large chorioangioma near the site of cord insertion and unassociated with complication
임신 중기 융모성 성선자극호르몬의 원인불명 상승과 임신성 고혈압 사이의 연관성
최미영(Mi Young Choi),김미란(Mi Ran Kim),김은규(Eun Kew Kim),김현진(Hyun Jin Kim),김미희(Mi Hee Kim),황혜란(Hye Ran Hwang) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.9
Objective : We conducted this study to determine whether women with unexplained elevations of midtrimester human chorionic gonadotropin (hCG) are at increased risk for poor pregnancy outcomes, especially pregnancy-induced hypertension (PIH).Methods : During 1998, 4314 women with singleton pregnancies at 16-21 weeks' gestation were screened triple test at our hospital. Alpha fetoprotein (AFP) level greater than 2.5 multiples of the median (MoM), insulin-dependent diabetes mellitus, and essential hypertension were excluded from this study. 304 women had hCG level greater than 2.0 MoM without fetal chromosomal abnormality and were defined as unexplained elevated group. 300 women with hCG level less than 2.0 MoM were randomly selected as normal referent group. Risks for poor pregnancy outcomes including PIH, small for gestational age (SGA), preterm delivery, and fetal death in uterus (FDIU) were evaluated. The linear trend in risk between the level of hCG and PIH was analyzed.Results : Unexplained elevated group had a significantly higher risk for PIH (9.87% versus 2.33%; P=0.001) than normal referent group, but there were no significant differences between two groups with respect to SGA, preterm delivery, and FDIU. The magnitude of the risk correlates with the level of hCG (P<0.01).Conclusion : Unexplained elevations of midtrimester hCG may be considered as a predictive factor for PIH.