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인삼 Saponin, 은시호 Saponin 및 계면활성제가 적혈구의 용적변화 및 Fragility에 미치는 영향
이신웅(Shin Woong Lee),이정수(Jeung Soo Lee),이수근(Soo Kun Lee),옥창건(Chang Kun Ok),김영희(Young Hie Kim) 대한약학회 1989 약학회지 Vol.33 No.1
The effects of Gypsophila saponin, sodium dodecylsulfate (SDS) and Triton X-100 on volume changes and fragility of red blood cells were compared to ginseng saponin to elucidate whether there are any difference in their action on membrane lipid. Cell volume was decreased to about 38% in 1M NaCl and increased to about 20% in 1/10M NaCl. Hematocrit value was decreased by Gypsophila saponin, SDS, and Triton X-100 which caused hemolysis in isotonic NaCl solution. These detergents also inhibited increase of cell volume and accelerated hemolysis in hypotonic solution. However, ginseng saponin did not influence to osmotic volume changes and hemolysis of red blood cells. These results suggest that the disruptive effect of plant saponin on membrane barriers induced by removing membrane lipid is different from their source and ginseng saponin has very low affinity to membrane lipid.
金英嬉,李正秀,蘇三燮,陳甲德 嶺南大學校 環境問題硏究所 1989 環境硏究 Vol.8 No.2
Effect of water and ethanol extract of Rheum coreanum N. on changes of pH in different NaC1 concentration and temperature in Juicy Kimchi was investigated and then, compared with it to sodium benzoate. The following results were obtained. 1. Addition of 0.03% water and ethanol extract of Rheum coreanum N. to juicy Kimchi preserved above pH 4.0 in whole experimental period at 30℃. 2. Addition of 0.1% water extract of Rheum coreanum N. induced less pH changes than control and preserved above pH 4.5 after 7 day at 18℃. 3. It was observed that water estract of Rheum coreanum N. was greater than ethanol extract in preservative potency. 4. Preservative potency of 0.03% water extract of Rheum coreanum N. was superior to 0.1% sodium benzoate. 5. Addition of 0.03% water extract of Rheum coreanum N. prolonged the tasty period of juicy Kimchi, which was more effective than sodium benzoate.
金英姬,朴洸立,李壽根,陳甲德 영남대학교 자원문제연구소 1989 資源問題硏究 Vol.8 No.-
Two compounds with bitter taste, comp.I (m.p. 138-141°C, white powder)and comp. II (m.p114-l17°C, white powder), were isolated from the leaves of Jasminum nudifluorum Lindl, respectively, and identified as iridoid compounds by the UV, IR, PMR, CMR and MS spectral data.
金英嬉,李正秀,李神雄,陳甲德 영남대학교 자원문제연구소 1989 資源問題硏究 Vol.8 No.-
Effects of alkaloid substance from flos of firmiana plantanifolia on the isolated duenal movement and phosphodiesterase activity were compared to those of caffeine. Rf value and melting point of crystalline alkaloid of translucent radial shape were 0.69 and 136.5~140°C, while those of caffeine of silky needle shape from CHCl3 as a solvent 0.61 and 235~238.5°C, respectively. Alkaloid inhibited the duodenal movement and brain phosphodiesterase(PDE) activity. Caffeine however, showed the biphasic effect on the duodenal movement which enhanced and inhibited "in low-and high-dose" , respectively, and inhibitory action of alkaloid on PDE activity was more potent than that of caffeine.
陳甲德,裵基哲,李正秀,金英姬 嶺南大學校 環境問題硏究所 1989 環境硏究 Vol.9 No.1
It was investigated Cadmium eliminating capacty of Quartz Porphyry(Q.P.) during washing, swelling, and cooking process in rice contaminated artificially. 1. After washing the rice four times with water, the eliminating rate of Cadmium from artificially contaminated sample were 16% in control group, 28% and 42% in 25g/kg and 50g/kg Q.P. treated group, respectively. 2. Swelling of rice in water about 20 minutes didn't change the Cadmium level in Q.P. treated group. 3. Cadmium eliminating efficiency by cooking was significantly increased in Q.P. treated group (43~54%) compared to control group(31%). 4. These results suggest that treatment of rice with Q.P. is very effective to remove the Cadmium contamination in rice.
陳甲德,金英姬,李壽根,白琇鉉,李神雄 嶺南大學校 環境問題硏究所 1986 環境硏究 Vol.6 No.1
Some basic propeties of suppository bases containing cetyl alcohol(C), lanoline(L), and propylene glycol(P) were investigated in this study. The results were as follows. 1. Suppository could be molded easily in the higher amount of cetyl alcohol than that of lanoline or propylene glycol. 2. Suppository was molded by 28 kinds of different C:L:P ration could be soften in rectum temperature and the proper ratios of C:L:P to release sodium salicylate from suppository were 5:3:1, 3:1:2, 4:3:1, 5:3:2. 3. The softening times of suppository with these ratios of C:L:P were 9 min to 20 min. 4. Softening temperature and time were not changed after storage for 1, 11, 38, 54 days at 20℃ or 4℃ 5. The most appropriate ratio of this base was 5:3:1 in sodium salicylate suppository.
Algebra Structure on the Generalized Koszul Complex
Kim, Young Hie,Ko, Hyong June 연세대학교 자연과학연구소 1994 學術論文集 Vol.27 No.-
코줄 복체를 일반화하고 그 위에 곱의 연산을 정의하여 일반화된 코줄 복체가 차수붙은 미분대수가 됨을 보인다. In this paper we provide multiplicative structures for certain generalized Koszul complexes and make them into differential graded algebras such that the remaining complexes become differential graded(right) modules over these algebras.
陳甲德,李神雄,金英姬,白琇鉉,鄭炷燮 영남대학교 자원문제연구소 1990 資源問題硏究 Vol.9 No.-
The effect of methanol extract of Commelina communis L. (C.M.E. ) on blood glucose level in alloxan -diabetic rabbit and acute toxicity of C.M.E. were investigated. C.M.E. decreased blood glucose level significantly but did not affect the normal blood glucose level and LD50 was about 6.250 mg / kg.
개 心臟形質膜의 Na^+-Ca^2+ 交換에 미치는 Diltiazem 및 Nitrendipine의 影響
李神雄,李正秀,金英姬,李光淳 영남대학교 자원문제연구소 1986 資源問題硏究 Vol.5 No.-
The effect of diltiazem and nitrendipine on the Na+-Ca2+ exchange and the Ca2+-efflux of highly purified sarcolemmal vesicles prepared from dog ventricles was investigated. Na+-loaded vesicles rapidly accumulated Ca2+ when an outwardly directed Na+ gradient was generated across the vesicle membrane. Na+-dependent Ca2+ uptake reached to a steady state level of about 40 nmol/mg protein at 5 minutes. The passive Ca -efflux of sarcolemmal vesicles which were first preloaded with 45Ca2+ by Na+-Ca2+ exchange was induced in Na+ and Ca2+ free potassium medium, and the maximal levels of Ca2+ effluxed passively were about 40% of those loaded initially. Both Na+-dependent Ca2+ uptake and efflux of Ca2+ were not affected by diltiazem or nitrendipine, calcium antagonist. These results indicate that diltiazem and nitrendipine have no direct action on the Na2+-Ca2+ exchange of nonpolarized sarcolemmal vesicles.
陳甲德,李神雄,金英姬,李正秀 영남대학교 자원문제연구소 1990 資源問題硏究 Vol.9 No.-
The isolated bitter principle from Ligustrum lucidum Ait was identified and it's influences to the rabbit's kidney function were investigated. On the basis of the spectroscopic and chemical data the isolated bitter principle was identified as a Ligusteroside, a secoiridoid glucoside. It decreased the renal plasma flow, glomerular filtration rate, and urinary excretion of sodium and potassium, concomitant with the decrease in urine flow on rabbit's kidney. These results suggest that the antidiuresis might be induced by the hemodynamic changes.