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      • 1985년 한국에서 발생한 Scrub Typhus 환자의 혈청진단 및 임상역학적 조사

        주용규,富山 哲雄,전성주,김민자,박승철,최경열,김연수,이호왕 대한감염학회 1988 감염 Vol.20 No.2

        Serological studies were performed on the 2,135 sera from the suspected Hemorrhagic fever with renal syndrome patients in 1985 and 64 scrub typhus patients were diagnosed serologically. Serotypes of etiologic agents, epidemiology and clinical features of the patients with scrub typhus were analyzed. The results were summarized as follows. 1) Among the 64 patients were infected with Rickettsia tsutsugamushi Karp type, 22 patients were infected with Gilliam type and only two patients were infected with Kato type. The remaining 16 patients had antibodies against more than two serotypes of R. tsutsugamush at the same time. 2) The regional occurrence of the patients showed that 33 patients occurred in Kyunggi province and the remaining patients were occurred in all over the Korea. 3) Fifty three of the 64 patients were female and 11 were male. More than a half of the patiens were in age groups of 50-70. 4) As the clinical features, most of the patients showed fever, chill, general weakness and myalgia however, abdominal pain, sputum and dyspnea were not uncommon. Clinical signs such as tachycardia, tachypnea, pharyngeal and conjunctival injection and abdominal tenderness were common but hepatomegaly, hypotension, rales, and edema were uncommon. 5) The laboratory findings showed frequently elevation of transaminase and abnormal chest X-ray, and leukocytosis, thrombocytopenia and abnormal urinary sedimetns were not uncommon. 6) Most of the patients showed one to three weeks of fever and then gradual improvement, but two were died of pulmonary edema. 7) Because most of the patients occurred in autumn, during the epidemic season of HFRS and leptospirosis, the differential serologic diagnosis among the diseases is absolutely demanded.

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